359 results match your criteria: "CNRS UPR 3212 & University of Strasbourg[Affiliation]"

Gryllus madagascarensis (Orthoptera: Gryllidae) is a cricket species that shows promise to mitigate food insecurity and malnutrition. But whether this species will accept low- to no-cost weeds and agro by-products as feed, and how these feeds affect its performance, remains unknown. This study assessed the acceptability of 66 weed species and agro by-products (derived from a single plant species) by adult G.

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Pupillary response to blue light as a biomarker of seasonal pattern in Major Depressive Episode: A clinical study using pupillometry.

Psychiatry Res

December 2024

Département de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat - Claude Bernard, F-75018 Paris, France; Université Paris Cité, NeuroDiderot, Inserm, FHU I2-D2, F-75019 Paris, France; Centre ChronoS, GHU Paris - Psychiatrie & Neurosciences, 1 rue Cabanis, 75014 Paris, France; CNRS UPR 3212 & Strasbourg University, Institute for Cellular and Integrative Neurosciences, F-67000, Strasbourg, France. Electronic address:

Depressive disorders are characterized by disturbances in light signal processing. More specifically, an alteration of the melanopsin response is suggested. The post-illumination pupillary response (PIPR) to blue light (post-blue PIPR) is increasingly used as a marker of the activity of intrinsically photosensitive melanopsin ganglion cells (ipRGCs).

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[Treatment of posttraumatic nightmares: the role of imagery rehearsal therapy].

Rev Prat

November 2024

Psychiatre, service de psychiatrie de l'enfant et de l'adolescent, pôle psychiatrie, santé mentale et addictologie, Hôpitaux universitaires de Strasbourg, Strasbourg, France. Centre régional du psychotraumatisme Alsace-Nord, pôle psychiatrie, santé mentale et addictologie, Hôpitaux universitaires de Strasbourg, Strasbourg, France. CNRS UPR 3212, Institut des neurosciences cellulaires et intégratives, Strasbourg, France.

Article Synopsis
  • Post-traumatic stress disorder (PTSD) affects about 30% of adults following a traumatic event, often leading to persistent sleep disturbances and nightmares that cause significant emotional distress.
  • Over 70% of PTSD patients experience post-traumatic nightmares, which are considered one of the earliest symptoms and are not effectively treated by standard PTSD treatments.
  • Imagery rehearsal therapy, a first-line treatment for these nightmares, uses mental imagery and cognitive restructuring techniques, and has been shown to improve the frequency of nightmares, insomnia severity, sleep quality, and overall PTSD symptoms.
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Nociception is defined as "the neural process of encoding noxious stimuli" by the International Association for the Study of Pain (IASP). Nociception relies on detecting noxious stimuli arising from a potentially or actually tissue-damaging event via specialized cells called nociceptors. In planarians, nociceptive behavior is often indicated by a 'scrunching' gait, in contrast to the usual gliding behavior displayed in normal conditions.

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Effects of Approved Pharmacological Interventions for Insomnia on Mood Disorders: A Systematic Review.

Clin Neuropsychiatry

October 2024

Department of Surgical, Medical and Molecular Pathology, Critical and Care Medicine, University of Pisa, Pisa, Italy, Department of Neuroscience, Azienda Ospedaliera Universitaria Pisana (AUOP), Pisa, Italy.

Objective: Insomnia can be a contributing factor, a comorbid disorder, or a transdiagnostic element to several mental disorders, including mood disorders (MDs). A recent meta-analysis has already shown the effectiveness of cognitive behavioral treatment (CBT) for insomnia that is comorbid with MDs. This work aimed to systematically review data on pharmacological insomnia treatment in the context of MDS.

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Article Synopsis
  • The study investigates how different feeds made from weeds, agro-byproducts, and chicken feed affect the growth and nutritional value of field crickets, a potential solution for global malnutrition.
  • Various feed formulations were tested, showing that those with higher protein content led to better growth rates and survivorship, with significant differences in body mass and length observed between the crickets fed formulated feeds versus the control.
  • The results suggest that using alternative feeds like weeds and agro-byproducts can enhance the growth and nutrition of crickets, making them a more sustainable food resource while also reducing feeding costs.
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Complete resolution of restless legs syndrome following ischemic stroke of the right middle cerebral artery.

Sleep Biol Rhythms

October 2024

CIRCSom (International Research Center for ChronoSomnology) & Sleep Disorder Center, Strasbourg University Hospital, 1 Place de L'Hôpital, 67000 Strasbourg, France.

Stroke-related restless legs syndrome (sRLS) is an emerging clinical entity, with a clear relationship between stroke and the occurrence of restless legs syndrome (RLS). Dopamine dysregulation has been observed in sRLS of the lenticulostriate region with increased dopamine precursor and decreased dopamine transporter. The aim of this work is to explore an original case of regressive RLS following stroke.

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Smoking and diabetes.

Ann Endocrinol (Paris)

December 2024

Champagne-Ardenne University, UMR CNRS 7369 MEDyC & Cardio-Thoracic Department, Reims University Hospital, Reims, France.

Article Synopsis
  • Smoking contributes to insulin resistance and negatively impacts beta-cell function, both of which are poorly understood factors linked to the development of type-2 diabetes.
  • Active smoking harms glycemic control in both type-1 and type-2 diabetics, increasing all-cause mortality and exacerbating diabetes-related complications, while its effects on specific complications are still debated.
  • There’s a lack of comprehensive data on smoking cessation strategies tailored for diabetic patients, highlighting the need for diabetes specialists to actively engage in supporting smoking cessation efforts.
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Depression is associated with dysregulated circadian rhythms, but the role of intrinsic clocks in mood-controlling brain regions remains poorly understood. We found increased circadian negative loop and decreased positive clock regulators expression in the medial prefrontal cortex (mPFC) of a mouse model of depression, and a subsequent clock countermodulation by the rapid antidepressant ketamine. Selective Bmal1KO in CaMK2a excitatory neurons revealed that the functional mPFC clock is an essential factor for the development of a depression-like phenotype and ketamine effects.

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States of consciousness and interoceptive hypersensibility: A study in patients with insomnia disorder.

J Sleep Res

August 2024

Department of Psychiatry and Addiction Medicine, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat-Claude Bernard, Paris, France.

This exploratory study aimed to investigate the relationship between interoceptive sensibility and quality of consciousness in individuals with insomnia disorder, in order to understand how the modulation of internal states may contribute to modifying the experience of consciousness during sleep difficulties. A total of 37 patients with insomnia disorder (mean age = 46.05 ± 18.

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Predictive factors of cognitive impairment in alcohol use disorder inpatients.

Addict Behav

November 2024

UFR de Médecine, Université Paris Cité, 85 boulevard Saint-Germain, 75006 Paris, France; Département de psychiatrie et d'addictologie, AP-HP, DMU Neurosciences, Hôpital Bichat - Claude Bernard, APHP GHU Nord, 46 rue Henri Huchard, 75018 Paris, France; Centre ChronoS, GHU Paris - Psychiatry & Neurosciences, 1 rue Cabanis, 75014 Paris, France; CNRS UPR 3212, Institute for Cellular and Integrative Neurosciences, Strasbourg, France.

Background: Cognitive impairments are common in patients with AUD and worsen the prognosis of addiction management. There are no clear guidelines for screening cognitive impairments in hospitalized patients with AUD.

Methods: Fifty-seven patients with an AUD history who were admitted to an acute hospital and assessed by the addiction care team were included.

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The 32nd Ion Channels Meeting, 17th-20th September 2023, Sète, France.

Bioelectricity

June 2024

Laboratoire de Physiologie Cellulaire et Moléculaire UR-UPJV 4667, Université de Picardie, Amiens, France.

The 32nd Ion Channel Meetings were organized by the Ion Channels Association from September 17 to 20, 2023 in the Occitanie region (Sète). Researchers, post-docs and students from France, Europe and non-European countries came together to present and discuss their work on various themes covering the field of neuroscience, stem cells, hypoxia and pathophysiology cardiac. Through the plenary conference given by Professor Emilio Carbone and the 5 conferences organized by the scientific committee, attention was paid this year to autism, neuromotor and cardiac disorders and tumor aggressive processes.

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Hypersomnia spectrum disorders are underdiagnosed and poorly treated due to their heterogeneity and absence of biomarkers. The electroretinography has been proposed as a proxy of central dysfunction and has proved to be valuable to differentiate certain psychiatric disorders. Hypersomnolence is a shared core feature in central hypersomnia and psychiatric disorders.

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Exploring emotional regulation in insomnia with and without major depressive episode.

J Sleep Res

June 2024

Centre ChronoS, Département de psychiatrie et d'addictologie, GHU Paris Nord, DMU Neurosciences, AP-HP, Hôpital Bichat - Claude Bernard, Paris, France.

Previous studies have highlighted the pivotal role of emotional regulation impairment in the progression of depressive and insomnia disorders, individually. Nevertheless, to date, no study has undertaken a direct comparison of the emotional profiles in individuals experiencing insomnia with or without major depressive episode (MDE). In this study, our objective was to closely examine multiple aspects of emotional regulation among individuals experiencing insomnia, with or without concurrent depression.

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Modeling longitudinal relationships between sleep disturbances and depressed mood in postpartum: A cross-lagged panel design.

J Affect Disord

October 2024

Université Paris Cité, INSERM UMR1266, Institute of Psychiatry and Neurosciences, Team 1, Paris, France; Department of Psychiatry, AP-HP, Louis Mourier Hospital, F-92700 Colombes, France.

Background: This short communication explores the interrelationships between depressed mood and sleep disturbances in one-year postpartum period.

Methods: Utilizing data from the Interaction of Gene and Environment of Depression during PostPartum Cohort (IGEDEPP) involving 3310 French postpartum women, we employed a cross-lagged panel model (CLPM) to analyze the relationships between these two symptoms, across three time points (immediate postpartum [<1 week after delivery], early postpartum [<2 months after delivery], and late postpartum [2 months to 1 years after delivery]).

Results: Depressed mood significantly influences sleep disturbances in late postpartum (β = 0.

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Problematic gaming, psychiatric comorbidities, and adolescence: A systematic review of the literature.

Addict Behav

October 2024

University Hospitals of Strasbourg, Department of Addiction Medicine, 67000 Strasbourg, France; INSERM 1329, Team Addictions, Strasbourg Translational Neuroscience & Psychiatry Unit, CRBS, 1 Rue Eugène Boeckel, 67000 Strasbourg, France. Electronic address:

Problematic gaming is particularly prevalent in adolescent and young adult populations. While numerous studies have investigated the psychiatric comorbidities of Internet Gaming Disorder in young adults, few have focused specifically on adolescents who might be especially at risk because developmental particularities related to this developmental period. Here, we conducted a review of the literature, in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, in order to highlight the types of psychiatric comorbidities found in adolescents with problematic gaming.

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Assessing chronotype is essential in clinical and research environments, but the Munich ChronoType Questionnaire (MCTQ), a widely utilised tool, is not available in French. Therefore, we carried out an observational monocentric study to validate the French MCTQ against the sleep diary for sleep schedules, the Morningness-Eveningness Questionnaire (MEQ) for chronotype, and polysomnography measures. We utilised the mid-sleep point on free days (MSF), adjusted for sleep debt (MSFsc), to gauge morningness/eveningness.

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Introduction: Pain mostly arises because specialized cells called nociceptors detect harmful or potentially harmful stimuli. In lower animals with less convoluted nervous system, these responses are believed to be purely nociceptive. Amongst invertebrate animal models, planarians are becoming popular in a wide range of pharmacological and behavioral studies beyond the field of regeneration.

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Digital therapeutic programs are emerging almost daily, offering the potential to reduce healthcare access inequalities by providing more flexible and accessible care options. However, as with traditional healthcare, the issue of patient engagement is fundamental, and the latest research have reported that fewer than 30% of users complete these programs in their entirety. Hence, many authors emphasize the importance of studying the role of therapeutic alliances specifically adapted to digital care.

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Article Synopsis
  • Gryllus bimaculatus, a cricket species, is recognized as a valuable source of nutrition for food and feed, but its response to temperature for effective mass production is not well-studied.
  • The research tested G. bimaculatus at temperatures from 20°C to 40°C, finding optimal life cycle completion and growth at around 32°C, with the highest population growth rate at 35°C.
  • Results provide crucial insights for farmers by revealing that G. bimaculatus can thrive in temperatures between 20°C and 37°C, allowing for better management and sustainability in cricket farming globally.
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Study of the different sleep disturbances during the prodromal phase of depression and mania in bipolar disorders.

Bipolar Disord

August 2024

Département de Psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat - Claude Bernard, Paris, France.

Background: One of the challenges in bipolar disorder (BD) lies in early detection of the illness and its recurrences, to improve prognosis. Sleep disturbances (SD) have been proposed as reliable predictive markers of conversion. While preliminary studies have explored the relationship between SD and the onset of mood episodes, the results remain heterogeneous and a few have specifically examined patients' perception of prodromal symptoms and their progression until the episode occurs.

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The PAP-RES algorithm: Defining who, why and how to use positive airway pressure therapy for OSA.

Sleep Med Rev

June 2024

Physical Exercise and Clinical Physiology Department, CHU Nord, Saint-Étienne, France; INSERM U1059 Santé Ingénierie Biologie, Université Jean Monnet, Saint-Étienne, France. Electronic address:

Obstructive sleep apnea (OSA) is a common condition that is increasing in prevalence worldwide. Untreated OSA has a negative impact on health-related quality of life and is an independent risk factor for cardiovascular diseases. Despite available data suggesting that cardiovascular risk might differ according to clinical phenotypes and comorbidities, current approaches to OSA treatment usually take a "one size fits all" approach.

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Thirty-seven years of MT1 and MT2 melatonin receptor localization in the brain: Past and future challenges.

J Pineal Res

April 2024

Regulation and Disruption of Neuroendocrine Rhythms, Institute of Cellular and Integrative Neurosciences, INCI CNRS UPR-3212, University of Strasbourg, Strasbourg, France.

Identifying the target cells of a hormone is a key step in understanding its function. Once the molecular nature of the receptors for a hormone has been established, researchers can use several techniques to detect these receptors. Here I will review the different tools used over the years to localize melatonin receptors and the problems associated with each of these techniques.

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