3,549 results match your criteria: "CNRS UMR6293-Université Clermont Auvergne[Affiliation]"

Rising interest in artificial intelligence in education reinforces the demand for evidence-based implementation. This study investigates how tutor agents' physical embodiment and anthropomorphism (student-reported sociability, animacy, agency, and disturbance) relate to affective (on-task enjoyment) and cognitive (task performance) learning within an intelligent tutoring system (ITS). Data from 56 students (M = 17.

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Importance: Amid escalating mental health challenges among young individuals, intensified by the COVID-19 pandemic, analyzing postpandemic trends is critical.

Objective: To examine mental health care utilization and prescription rates for children, adolescents, and young adults before and after the COVID-19 pandemic.

Design, Setting, And Participants: This population-based time trend study used an interrupted time series analysis to examine mental health care and prescription patterns among the French population 25 years and younger.

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Relationship Between the Structure of the Flavone -Glycosides of Linseed ( L.) and Their Antioxidant Activity.

Molecules

December 2024

UMRT INRAE 1158 BioEcoAgro, BIOlogie des Plantes et Innovation (BIOPI), Université de Picardie Jules Verne, IUT GB, Avenue des Facultés, Le Bailly, 80025 Amiens, France.

Flavonoids have been documented to have good antioxidant activities in vitro. In recent years, reports on the antioxidant activities of flavone glycosides, a subclass of flavonoids, have attracted great attention. Despite the wealth of information on this subject, the correlation between structure and function is not well understood.

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Reproductive success is dependent on gamete integrity, and oxidative stress alters male nuclei, meaning that no DNA repair is possible due to chromatin compaction. The composition of sperm makes it highly sensitive to reactive oxygen species (ROS) but, at the same time, ROS are needed for sperm physiology. Over the past 30 years, much attention has been paid to the consequences of oxidative stress on sperm properties and the protective effects of antioxidant formulations to help fertility.

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[Not Available].

Can J Psychiatry

January 2025

CHU Clermont-Ferrand, Psychiatrie B, Clermont-Ferrand F-63003, France.

Background: Although self-esteem is a relatively new concept, first developed in the field of social psychology, it has gained increasing importance in psychiatry, especially as a diagnostic criterion. However, it is poorly evaluated in clinical practice. The lack of an instrument allowing an easy global assessment may be the reason for this.

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AMETIS Preplanned Ancillary Study: Impact of Agitation During Mechanical Thrombectomy Under Sedation.

Stroke

January 2025

Anesthésie et Neuro-Réanimation chirurgicale Babinski, Département d'Anesthésie-Réanimation, Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalier Pitié-Salpêtrière, Sorbonne Université, France (C.T., R.B., A.J., V.D.).

Article Synopsis
  • Mechanical thrombectomy is a common treatment for ischemic strokes, but sedation during the procedure can cause agitation in patients.
  • This study, part of the AMETIS research, evaluated patients who experienced agitation and found that 38% had at least one episode during the procedure.
  • Although agitation didn’t significantly affect thrombolysis scores or overall outcomes, it did correlate with a higher need for intubation and poorer radiological image quality.
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We investigated people living with HIV (PLWH)'s exposure to COVID-19 pandemic stressors and their association with distress, psychological growth, and substance use. PLWH in the ANRS CO3 AQUIVIH-NA cohort's QuAliV study (Nouvelle Aquitaine, France) completed an adapted CAIR Lab Pandemic Impact Questionnaire (C-PIQ) and reported substance use between 9/2021 to 3/2022. We described cumulative stressor exposure (score 0-16) and explored variation by PLWH characteristics (demographic, HIV-related, risk factors, psychosocial).

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Efficacy of valaciclovir in preventing herpes zoster in patients receiving anifrolumab.

RMD Open

January 2025

Assistance Publique-Hôpitaux de Paris (AP-HP), Groupement Hospitalier Pitié-Salpêtrière, Centre de Référence des maladies auto-immunes et auto-inflammatoires systémiques rares de l'adulte d'Ile-de-France, Centre et Martinique, Service de Médecine Interne 2, Institut E3M, Paris, France, paris, France.

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Age-based stereotype threat effects: From the laboratory to the clinical setting.

Cortex

December 2024

Laboratory of Social and Cognitive Psychology, Université Clermont Auvergne, CNRS, Clermont-Ferrand, France.

Age-Based Stereotype Threat (ABST) adversely affects older adults' memory performance by inducing anxiety and interfering thoughts related to negative stereotypes about aging and memory decline. While well-documented in laboratory settings, the relevance of ABST in real-life clinical contexts remains underexplored. This narrative review examines the effects of ABST and its implications for cognitive aging, emphasizing the importance of addressing ABST in clinical settings.

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Validation and safety of AmbuLatory care for transient ischemic attack from emergency department (VALID study).

J Clin Neurosci

January 2025

CHU Clermont-Ferrand, Emergency Department, F-63000 Clermont-Ferrand, France; Université Clermont Auvergne, CNRS, LaPSCo, Physiological and Psychosocial Stress, F-63000, Clermont-Ferrand, France. Electronic address:

Background: Transient Ischemic Attacks (TIAs) are a common reason for Emergency Department (ED) visits and represent a significant public health issue. Patients experiencing TIAs often face significant delays in undergoing various tests due to ED overcrowding and limited availability of neurologists. Emergency physicians (EPs) and neurologists have identified several criteria for allowing outpatient management.

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High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

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Measurement of CP Violation Observables in D^{+}→K^{-}K^{+}π^{+} Decays.

Phys Rev Lett

December 2024

Institute of Physics, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Article Synopsis
  • The study investigates CP symmetry violation in the decay of D^{+} particles into K^{-}K^{+}π^{+} using data from proton-proton collisions at a high energy of 13 TeV.
  • A unique model-independent method was employed to analyze the phase-space distributions of D^{+} and D^{-} particles, correcting for any instrumental biases using D_{s}^{+} decays.
  • The findings indicate no significant evidence of CP violation, with a p value of 8.1%, and measure specific CP asymmetry observables, marking this study as the most sensitive search of its kind in multibody decays.
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Hibernating brown bears, due to a drastic reduction in metabolic rate, show only moderate muscle wasting. Here, we evaluate if ATPase activity of resting skeletal muscle myosin can contribute to this energy sparing. By analyzing single muscle fibers taken from the same bears, either during hibernation or in summer, we find that fibers from hibernating bears have a mild decline in force production and a significant reduction in ATPase activity.

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[Peginterferon alfa-2a monotherapy in essential thrombocythemia].

Bull Cancer

December 2024

Service de thérapie cellulaire et hématologie clinique, CHU de Clermont-Ferrand, 63100 Clermont-Ferrand, France; EA7453 CHELTER, université Clermont-Auvergne, Clermont-Ferrand, France.

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Unlabelled: The Hospital Anxiety and Depression Scale (HADS) is commonly used to detect depressive or anxious states, but its 14-item questionnaire is time-consuming. Visual analog scales (VAS) are easy to use and quick to implement. Although the VAS has been validated to assess pain and occupational stress, VAS scores for anxiety and mood have never been evaluated in the workplace.

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The parasitic wasp, Cotesia congregata, manipulates the behaviour of its host, the caterpillar Manduca sexta. The female wasp injects her eggs and a symbiotic virus (i.e.

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Reaction kinetics and molecular characterization of the compounds formed by photosensitized degradation of the plastic additive bisphenol A in the atmospheric aqueous phase.

Sci Rep

December 2024

State Key Laboratory of Organic Geochemistry and Guangdong Provincial Key Laboratory of Environmental Protection and Resources Utilization, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China.

Bisphenol A (BPA, 4,4'-(propane-2,2-diyl)diphenol) is a common plasticizer that is very widespread in the environment and is also found at significant concentrations in the global oceans, due to contamination by plastics. Here we show that triplet sensitization is an important degradation pathway for BPA in natural surface waters, which could prevail if the water dissolved organic carbon is above 2-3 mg L. Bromide levels as per seawater conditions have the potential to slow down BPA photodegradation, a phenomenon that could not be offset by reaction of BPA with Br (second-order reaction rate constant of (2.

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The new submarine volcano Fani Maoré offshore Mayotte (Comoros archipelago) discovered in 2019 has raised the awareness of a possible future eruption in Petite-Terre island, located on the same 60 km-long volcanic chain. In this context of a renewal of the volcanic activity, we present here the first volcanic hazard assessment in Mayotte, focusing on the potential reactivation of the Petite-Terre eruptive centers. Using the 2-D tephra dispersal model HAZMAP and the 1979 - 2021 meteorological ERA-5 database, we first identify single eruptive scenarios of various impacts for the population of Mayotte.

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Microscopic image segmentation (MIS) is a fundamental task in medical imaging and biological research, essential for precise analysis of cellular structures and tissues. Despite its importance, the segmentation process encounters significant challenges, including variability in imaging conditions, complex biological structures, and artefacts (e.g.

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Fumagillin Shortage: How to Treat Microsporidiosis in Solid Organ Transplant Recipients in 2024?

Transpl Int

December 2024

Service de Parasitologie-Mycologie, 3IHP, Inserm U1071, M2iSH, USC-INRAE 1382, Université Clermont Auvergne, CHU Clermont-Ferrand, Clermont-Ferrand, France.

Unlabelled: Intestinal microsporidiosis caused by is an opportunistic infection that especially affects solid organ transplant (SOT) recipients. Management revolves around tapering the immunosuppressive regimen and/or using a specific anti-microsporidia treatment, but only fumagillin has demonstrated efficacy for treatment of this infection. Since fumagillin has been commercially discontinued, nitazoxanide is increasingly being used in this indication.

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Distinct pathophysiological pathways support stratification of Sjögren's disease based on symptoms, clinical, and routine biological data.

Arthritis Rheumatol

December 2024

Department of Rheumatology, Hôpital Bicêtre, Assistance Publique - Hôpitaux de Paris, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

Objective: Recently, three distinct phenotypes of Sjögren's disease (SjD) patients have been described, based on cluster analysis: B-cell active with low symptoms (BALS), high systemic activity (HSA), and low systemic activity with high symptoms (LSAHS). We aimed to assess whether these clusters were associated with distinct biomarkers and the prognostic value of IFN signature.

Methods: The ASSESS cohort is a 20-year prospective cohort of SjD patients.

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Photochemical reactions of biomass derived platform chemicals.

Front Chem

December 2024

Biomolécules: Conception, Isolement et Synthèse (BioCIS), UMR CNRS 8076, Université Paris-Saclay, Orsay, France.

Platform chemicals obtained from biomass will play an important role in chemical industry. Already existing compounds or not yet established chemicals are produced from this renewable feedstock. Using photochemical reactions as sustainable method for the conversion of matter furthermore permits to develop processes that are interesting from the ecological and economical point of view.

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What is the lower limb length discrepancy after arthroplasty for proximal femoral fracture? A prospective, multicenter observational study of 590 hips.

Orthop Traumatol Surg Res

December 2024

Société Française de Chirurgie Orthopédique et Traumatologique, 56 rue Boissonade, 75014 Paris Cedex, France.

Introduction: Lower limb length discrepancy (LLD) following hip arthroplasty after proximal femoral fracture (PFFA) is little studied. The aim of this work was to answer the following questions: 1) What are the incidence and mean values ​​of LLD after PFFA? 2) What are the clinical consequences (tolerance) of LLD after PFFA? 3) Can we identify risk factors for LLD after PFFA? 4) Is there a significant difference in terms of LLD after PFFA to treat intra- versus extra-capsular fractures?

Hypothesis: LLD after proximal femoral fracture arthroplasty is rare but has good clinical tolerance, given the low functional demands of the patients.

Patients And Methods: This is a multicenter prospective observational cohort study (15 centers), including 590 patients, operated on for hip arthroplasty for proximal femur fracture between May 2022 and June 2023.

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The increasing presence of emerging pollutants (EPs) in water poses significant environmental and health risks, necessitating effective treatment solutions. Originating from industrial, agricultural, and domestic sources, these contaminants threaten ecological and public health, underscoring the urgent need for innovative and efficient treatment methods. TiO-based semiconductor photocatalysts have emerged as a promising approach for the degradation of EPs, leveraging their unique band structures and heterojunction schemes.

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