The study aimed to evaluate the impact of the calcimimetic Etelcalcetide on secondary hyperparathyroidism in end-stage renal disease patients undergoing hemodialysis, comparing its effects to those in patients not treated with calcimimetics.
A total of 203 patients were included, with 71 receiving Etelcalcetide and 132 in a historical control group, and results measured included changes in serum levels of parathyroid hormone, calcium, and phosphorus over 12 months, focusing on mortality and cardiovascular events.
Results showed significant decreases in parathyroid hormone levels and cardiovascular event rates in the Etelcalcetide group compared to the historical group, suggesting a notable benefit of the treatment in reducing complications associated