1 results match your criteria: "CNC-UC-Center for Neuroscience and Cell Biology of the University of Coimbra[Affiliation]"
Cell wall nanoparticles from hyphae of grown with caspofungin, nikkomycin, or pyroquilon trigger different activation profiles in macrophages.
Microbiol Spectr
November 2024
Univ Coimbra, CNC-UC-Center for Neuroscience and Cell Biology of the University of Coimbra, Coimbra, Portugal.
Article Synopsis
- This study focuses on cell wall nanoparticles (CWNPs) derived from fungal hyphal cell walls to explore how they affect macrophage immune responses.
- CWNPs were produced using various inhibitors, leading to distinct types that showed different impacts on macrophage activation and viability.
- The findings suggest that modifying fungal cell walls results in nanoparticles with unique properties, which may influence immune reactions and therapeutic strategies during antifungal treatments.