522 results match your criteria: "CMH Lahore Medical College & Institute of Dentistry[Affiliation]"

Climate change represents an unprecedented global public health crisis with extensive and profound implications. The Lancet Commission identified it as the foremost health challenge of the 21st century. In 2015, air pollution alone caused approximately 9 million premature deaths worldwide.

View Article and Find Full Text PDF

Background Melanoma, the most lethal form of skin cancer, contributes to a majority of skin cancer fatalities globally. It carries a grim prognosis with a high propensity for early metastasis. People are not aware of moles, their natural course of progression, and skin self-examination.

View Article and Find Full Text PDF

Posttraumatic stress disorder (PTSD) is seen in a substantial proportion of individuals experiencing trauma. The last few decades have been significant in terms of PTSD-related research; however, a quantitative charting of the evolution in evidence-based treatment modalities for PTSD is lacking. The objective of this study was to conduct a bibliometric analysis to bridge this gap in knowledge.

View Article and Find Full Text PDF
Article Synopsis
  • * Atrial fibrillation is marked by irregular heart activity that leads to changes in the atrial structure and function, while celiac disease results from an immune response causing intestinal damage linked to specific genetic mutations.
  • * The findings suggest a potential association between AF and CD due to inflammation and fibrosis, highlighting the need for awareness of AF risks in CD patients and the importance of integrated patient care, with more research needed to clarify their relationship and discover treatment options.
View Article and Find Full Text PDF

Objective: To evaluate the use of a multiplex real-time polymerase chain reaction (RT-PCR) test in detecting three viruses namely Rotavirus, Norovirus (genotypes 1 and 2), and Astrovirus that cause gastroenteritis in children under the age of five years.

Study Design: A cross-sectional study. Place and Duration of the Study: Department of Virology, Armed Forces Institute of Pathology (AFIP), Rawalpindi, Pakistan, from January to July 2023.

View Article and Find Full Text PDF

Background: A cardiac condition marked by excessive growth of heart muscle cells, hypertrophic cardiomyopathy (HCM) is a complex genetic disorder characterized by left ventricular hypertrophy, microvascular ischemia, myocardial fibrosis, and diastolic dysfunction. Obstructive hypertrophic cardiomyopathy (oHCM), a subset of HCM, involves significant obstruction in the left ventricular outflow tract (LVOT), leading to symptoms like dyspnea, fatigue, and potentially life-threatening cardiac events. With advancements in genetic understanding and the introduction of novel pharmacologic agents, including cardiac myosin inhibitors like mavacamten and aficamten, there is a paradigm shift in the therapeutic approach to oHCM.

View Article and Find Full Text PDF
Article Synopsis
  • Cancer is predicted to rise significantly, with 35 million new cases expected by 2050, mainly impacting low- and middle-income countries, particularly in the SAARC region.
  • There is a research investment and output gap in SAARC countries compared to high-income nations, leaving a lack of local studies and clinical trials in crucial areas like targeted therapy and immunotherapy.
  • Addressing the challenges of healthcare access, cultural and economic barriers, and limited funding in SAARC countries requires collaboration, improved research infrastructure, and local studies to develop practical and affordable cancer treatments.
View Article and Find Full Text PDF

Impact of eyesight, BMI, and the use of screen-based devices on mental well-being.

Pak J Med Sci

December 2024

Faiza Fatima Chishti, BDS, MSc Dental Public Health (UK) Department of Community & Preventive Dentistry, CMH Lahore Medical College and Institute of Dentistry, Lahore, Pakistan National University of Medical Sciences, Rawalpindi, Pakistan.

Article Synopsis
  • The study aimed to explore the relationship between mental health and factors like BMI, eyesight, and screen device usage among young adults aged 16-25.
  • Conducted at CMH Lahore Medical College, researchers collected data using a validated questionnaire and performed statistical analyses to examine mental well-being scores.
  • Results indicated that using only smartphones correlated with lower mental well-being scores, while underweight individuals and those with both hyperopia and myopia also reported lower scores.
View Article and Find Full Text PDF
Article Synopsis
  • * Irisin is a new anti-inflammatory protein linked to various inflammatory conditions, but its specific role in oral inflammation is not yet well understood, calling for further investigation.
  • * The review emphasizes the need for more research on salivary irisin to fully assess its potential as a diagnostic and therapeutic biomarker for both systemic and oral inflammatory diseases.
View Article and Find Full Text PDF

Objective: Craniosynostosis is a congenital skull deformity that impacts development and quality of life of children if left untreated. This study aimed to evaluate literature regarding presentation, treatment and outcomes of craniosynostosis in Africa.

Methods: A systematic review of the literature using PubMed/MEDLINE, SCOPUS, Web of Science and Google Scholar databases was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

View Article and Find Full Text PDF
Article Synopsis
  • - The study compares radial and femoral access during primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) patients, focusing on complications associated with each method.
  • - Results show that the radial access group had a significantly lower rate of complications (11.4% vs. 22.9%) and major bleeding events (2.3% vs. 8.6%), as well as shorter hospital stays (three days vs. five days).
  • - Despite these differences in complications and hospital stays, the procedural success rates were similar for both access sites (97.1% for radial vs. 94.3% for femoral).
View Article and Find Full Text PDF

Background: An episiotomy is a perineal incision performed to facilitate childbirth by enlarging the diameter of the vulvae outflow. This study used vicryl rapide suture, a polyglactin analogue that causes less tissue reactivity and is removed through hydrolysis (as opposed to chromic catgut suture), because long-term complications after episiotomy repair are common. Made of collagen, chromic catgut is broken down by proteolytic enzymes and phagocytosis, which causes an inflammatory response in the tissues.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effects of heterologous (different) and homologous (same) COVID-19 vaccine booster doses in healthy adults in Pakistan, focusing on immune responses nine months post-vaccination.
  • A total of 173 participants aged 18-25 received either Sinopharm BBIBP-CorV or Pfizer-BioNTech vaccines, with antibody levels measured to compare immune responses.
  • Results show that the Pfizer group had significantly higher IgG antibody levels compared to the Sinopharm group, suggesting that a third Pfizer dose after two Sinopharm doses enhances overall immune response, with no significant differences between genders.
View Article and Find Full Text PDF
Article Synopsis
  • - Stroke in adolescents and young adults is rare and presents unique challenges in identifying causes, as they often lack typical risk factors like high blood pressure, making diagnosis difficult.
  • - This literature review highlights significant gaps in understanding stroke in younger individuals, focusing on causes, risk factors, diagnosis, and treatment strategies while also addressing stroke mimics that can confuse clinicians.
  • - Although acute treatment methods for strokes in young patients are similar to those for older adults, there is an urgent need for more research on long-term care and the impacts of rising stroke rates in this age group.
View Article and Find Full Text PDF

The objective of this study was to find out the effect of the myofascial release technique combined with valgus correction exercise on the pain, range of motion, balance, and quality of life in participants with grade II knee osteoarthritis. Forty participants with grade II knee osteoarthritis were randomly assigned into two treatment groups in the present clinical trial; group A was the myofascial release group, and group B was the myofascial release with valgus correction exercises group. Measurement included pain, balance, range of motion, and quality of life, as measured through the visual analog scale (VAS), Berg balance scale (BBS), goniometer, and knee injury and osteoarthritis outcome score (KOOS), respectively.

View Article and Find Full Text PDF
Article Synopsis
  • The study focused on how psycho-trauma and perceived social support affect coping strategies in young adults aged 18-28 in Pakistan and Afghanistan, investigating various demographic factors like gender and education.
  • Data was collected from 352 participants using standardized questionnaires, revealing significant negative correlations between psycho-trauma and both perceived social support and problem-focused coping strategies.
  • Gender differences were noted, with men favoring problem-focused coping and women leaning towards emotion-focused coping, while various demographic factors influenced coping mechanisms.
View Article and Find Full Text PDF

Objective: To measure the readiness for self-directed learning among medical undergraduates of private and public medical colleges, and to evaluate their performance and strategies.

Methods: The cross-sectional study was conducted in Lahore, Pakistan from February to July 2023, and comprised medical undergraduate students of either gender from 1 private and 1 public academic institution. Data was collected using a prevalidated structured questionnaire having self-management, desire for learning, and self-control domains to explore self-directed learning readiness.

View Article and Find Full Text PDF
Article Synopsis
  • Oral cancer remains a significant public health issue globally, influenced by various lifestyle and socioeconomic factors, particularly among students in private colleges in Pakistan.
  • A study conducted over six months at two dental colleges in Lahore analyzed 430 students for prevalence and risk factors related to oral cancer using questionnaires and clinical exams.
  • Results indicated that a small percentage of students (5.58% at Azra Naheed and 8.84% at Rahbar) had oral lesions, with notable lifestyle habits such as tobacco use (32.22% and 28.89%) and a diet high in processed foods contributing to risk factors.
View Article and Find Full Text PDF
Article Synopsis
  • Ectopic ureteroceles are rare in adults but often found in children, typically discovered during pregnancy ultrasounds or through UTI symptoms.
  • A 24-year-old woman faced recurrent UTIs and severe urinary retention due to a large ectopic ureterocele, confirmed through imaging and cystoscopy.
  • The minimally invasive treatment led to her full recovery and emphasizes the need to consider ectopic ureteroceles in adult women with frequent urinary issues.
View Article and Find Full Text PDF
Article Synopsis
  • Temporal lobe epilepsy (TLE) is difficult to diagnose due to its varied presentations and reliance on MRIs and EEGs, which may lead to underdiagnosis.
  • Symptoms can include unusual behaviors and psychiatric issues, and treatment with antiepileptic medications should be considered even if tests appear normal.
  • A case study is presented where a patient with behavioral issues and recurrent loss of consciousness, despite normal test results, significantly improved after starting divalproex sodium, demonstrating the need for awareness of TLE indicators.
View Article and Find Full Text PDF

Introduction: The use of electronic cigarettes (ECs) has surged globally, particularly among young individuals. This study aimed to assess the perceptions of vaping-related oral health risks, clinical oral health status, and self-perceived dental and periodontal conditions among young adult users of ECs in Pakistan.

Methods: A cross-sectional study was conducted from June 2023 to March 2024, recruiting 142 young users of ECs.

View Article and Find Full Text PDF
Article Synopsis
  • Dengue-associated hemophagocytic lymphohistiocytosis (HLH) is a rare but serious complication of dengue fever, marked by an overactive immune response that can be life-threatening.
  • A case study describes a patient with existing health issues who experienced severe complications, including persistent fever, abdominal pain, and organ dysfunction, which led to the HLH diagnosis due to significant lab findings.
  • The patient received intensive care with treatments like high-dose dexamethasone and plasmapheresis, highlighting the importance of recognizing HLH as a potential dengue-related complication and the need for more research on effective diagnosis and management.
View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the effects of melatonin on the immune system of immunosuppressed male Wistar rats by measuring levels of Interleukin 6 (IL-6), total leucocyte counts (TLC), and different types of white blood cells.
  • Experiments involved treating groups of rats with cyclophosphamide and melatonin over a specified period and assessing the immune responses through blood tests.
  • Findings indicated that melatonin significantly increased IL-6 and TLC levels, suggesting it may help enhance immune functions in immunosuppressed states compared to other immunomodulators.
View Article and Find Full Text PDF