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Evaluation of TLR2 and 4 in Chronic Periodontitis.
J Clin Diagn Res
June 2016
Reader, Department of Periodontology, CKS Teja Dental College and Hospital, Tirupathi, Andhra Pradesh, India .
Introduction: Periodontal disease is the major cause of adult tooth loss and is commonly characterized by a chronic inflammation caused by infection due to oral bacteria. Members of Toll-Like Receptor (TLR) family recognize conserved microbial structures, such as bacterial lipopolysaccharides and activate signalling pathways that result in immune responses against microbial infections.
Aim: The aim of the present study was to assess the mRNA expression of Toll-Like Receptor 2 and 4 in tissues with or without chronic periodontitis.