Comparing the Efficacy of Two Cognitive Screening Tools in Identifying Gray and White Matter Brain Damage among Older Adults.

Background: Ageing is associated with structural changes in brain regions and functional decline in cognitive domains. Noninvasive tools for identifying structural damage in the brains of older adults are relevant for early treatment.

Aims: This study aims to evaluate and compare the accuracy of the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA©) in identifying gray and white matter brain damage in older individuals with varying degrees of cognitive impairment.

Bixa orellana ethyl acetate fraction and its isolated compound ellagic acid attenuate the progression of MIA-induced osteoarthritis in rat knees.

Osteoarthritis (OA) is a pathology that is characterized by progressive erosion of articular cartilage. In this context, medicinal plants have become relevant tools regarding their potential role in the prevention and treatment of OA, being safe and effective. The aim of this work was investigate the therapeutic efficacy of the ethyl acetate fraction of Bixa orellana leaves (BoEA) and ellagic acid (ElAc) for the therapeutic treatment of OA induced by monosodium iodoacetate (MIA) in rats.

Bibliometric Review on New Possibilities of Antimycobacterial Agents: Exploring Siderophore Desferrioxamine's Applications as an Antimicrobial Agent.

Mycobacteria cause tuberculosis and other serious diseases. Understanding their mechanisms of resistance to our immune system and exploring novel drugs are critical strategies to combat infections. A bibliometric analysis was performed to identify publication trends and critical research areas in the field of the antimicrobial activity of desferrioxamine.

Assessment of Functional Capacity in Patients with Nondialysis-Dependent Chronic Kidney Disease with the Glittre Activities of Daily Living Test.

This study evaluated the functional capacity measured by the Glittre-ADL test (TGlittre) in patients with nondialysis-dependent chronic kidney disease (NDD-CKD) and analyzed the test's associations with muscle strength, physical activity level (PAL), and quality of life. Methods: Thirty patients with NDD-CKD underwent the following evaluations: the TGlittre; the International Physical Activity Questionnaire (IPAQ); the Short Form-36 (SF-36); and handgrip strength (HGS). The absolute value and percentage of the theoretical TGlittre time were 4.

The study of rs324420 (C385A) polymorphism of the FAAH gene of the endocannabinoid system in patients with epilepsy and ADHD.

The endocannabinoid (eCB) system regulates many physiological functions in the central nervous system. Fatty acid amide hydrolase (FAAH) is an essential enzyme in the eCB system, degrading anandamide. Single nucleotide polymorphism (SNP) rs324420 is a common genetic polymorphism of the FAAH gene and has been associated with susceptibility to neurological conditions.

Decrease in CD8CD45CCR7CD62L T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection.

Vaccines induce antibodies, but T cell responses are also important for protection against Coronavirus disease 2019. Here, we analyzed the frequency of memory T cells in infected and/or vaccinated individuals and observed a decrease in central memory T cells in individuals who were vaccinated following COVID-19 infection.

Ethyl Acetate Fraction of and Its Component Ellagic Acid Exert Antibacterial and Anti-Inflammatory Properties against subsp. .

subsp. () causes chronic infections, which has led to the need for new antimycobacterial agents. In this study, we investigated the antimycobacterial and anti-inflammatory activities of the ethyl acetate fraction of leaves (BoEA) and ellagic acid (ElAc).

Effective connectivity within the corticothalamic circuit in the neuromyelitis optica patients: A comparative study using resting-state fMRI.

Neuromyelitis Optica, which is known as NMO, is a demyelination syndrome and inflammatory condition of the central nervous system that affects the optic nerves. Since structural imaging approaches cannot adequately describe the brain disorders in patients with NMO, functional magnetic resonance imaging (fMRI) can be used. Resting-state fMRI was performed on 25 healthy subjects and 26 NMO patients.

Interaction effect of Nd:YAG laser and universal adhesive system for dentin sealing.

Background: To evaluate the influence of the association of the universal adhesive system to different energy densities of the Nd:YAG laser on the hydraulic conductance of dentin.

Material And Methods: Fifty bovine dentin discs were made. The samples were stratified into four groups (n = 10) according to the treatment performed; SBU- Adper Single Bond Universal (3M ESPE), SBU_60 - SBU associated with the Nd:YAG laser (60mJ, 10Hz, 0.

Cognitive impairment in Parkinson's disease: A clinical and pathophysiological overview.

Cognitive dysfunction in Parkinson's disease (PD) has received increasing attention, and, together with other non-motor symptoms, exert a significant functional impact in the daily lives of patients. This article aims to compile and briefly summarize selected published data about clinical features, cognitive evaluation, biomarkers, and pathophysiology of PD-related dementia (PDD). The literature search included articles indexed in the MEDLINE/PubMed database, published in English, over the last two decades.

Metabolic syndrome and COVID-19: An update on the associated comorbidities and proposed therapies.

Background And Aims: Many patients with coronavirus disease 2019 (COVID-19) have comorbidities related to metabolic syndrome (MS) during the disease course. Its presence in different ethnicities and continents places MS as an important risk factor for COVID-19. Adequate understanding of the interplay between MS, COVID-19 and proposed therapies is required for optimum management of these patients.

Shear Strength of Brackets Bonded with Universal Adhesive Containing 10-MDP after 20,000 Thermal Cycles.

Objectives: The aim of this study was to evaluate the shear bond strength of metal brackets bonded with different universal adhesive systems containing 10-MDP and Transbond Plus Self Etching Primer after 20,000 thermal cycles. . A total of 130 sound bovine teeth were used, which are divided into 5 groups ( = 26) according to the adhesive system used: All-Bond Universal (Bisco), Ambar Universal (FGM), Clearfil Universal Bond (Kuraray), Single Bond Universal (3M/ESPE), and Transbond Plus SEP (3M/ESPE) as control.

Author Correction: Modelling Dunes from Lençóis Maranhenses National Park (Brazil): Largest dune field in South America.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Effect of Sonic Application of Self-Adhesive Resin Cements on Push-Out Bond Strength of Glass Fiber Posts to Root Dentin.

The aim of this study was to evaluate the influence of a sonic application of self-adhesive resin cements on the bond strength of glass fiber posts to root dentin. Eighty bovine incisors were randomly divided into eight groups ( = 10). Four self-adhesive resin cements were used-RelyX U200 (3M/ESPE), Bifix SE (Voco), seT PP (SDI), and Panavia SA (Kuraray).

Modelling Dunes from Lençóis Maranhenses National Park (Brazil): Largest dune field in South America.

This paper presents a digital elevation model (DEM) of the dunes found in the Lençóis Maranhenses National Park, an environmental protection area located in the Maranhão state (Brazil). The DEM supports the modeling studies of sand-dune evolution using multi-temporal satellite images and ground truth data, obtained through the post-processed kinematic Global Navigation Satellite System (GNSS) positioning. The study area is located at the border of three major neotropical ecosystems: the Amazonia, Caatinga, and Brazilian savanna.

Treatment with selenium-enriched Saccharomyces cerevisiae UFMG A-905 partially ameliorates mucositis induced by 5-fluorouracil in mice.

Purpose: Gastrointestinal mucositis is a major problem associated with cancer therapy. To minimize these deleterious effects, simultaneous administration of antioxidant components, such as selenium, can be considered. There is a growing interest in the use of yeasts because they are able to convert inorganic selenium into selenomethionine.

Dentogingival Alterations and Their Influence on Facial and Smile Attractiveness.

Aim: This study aimed to evaluate the influence of labial and dentogingival characteristics on facial and smile attractiveness.

Materials And Methods: Four different close-up photographs each of six women models with different labial and dentogin-gival characteristics were obtained. One of the models was considered standard.

Location of the course of the mandibular canal, anterior loop and accessory mental foramen through cone-beam computed tomography.

Purpose: This study aimed at identifying the course of the mandibular canal, the presence of anterior loop and accessory mental foramen, as well as verifying the association between these variables through the analysis of cone beam computed tomography (CBCT) exams.

Methods: CBCT images were analyzed to identify the type of mandibular canal path, classified into three types: (I) catenary; (II) progressive descending; and (III) straight. In addition, the presence of anterior loop and accessory mental foramen was analyzed.

Repair of Iatrogenic Furcal Perforation with Mineral Trioxide Aggregate: A Seven-Year Follow-up.

Teeth with furcal perforation present difficult resolution and dubious prognosis. Several materials have been proposed and calcium silicate-based cements such as mineral trioxide aggregate (MTA) are the most recommended. However, its long-term clinical behavior still remains poorly understood.

Effect of different endodontic sealers and time of cementation on push-out bond strength of fiber posts.

Objectives: This study aims to evaluate the effect of different endodontic sealers (epoxy resin, eugenol, and bioceramic/calcium silicate-based) and the time of cementation (immediately or 7 days after canal obturation) on the bond strength of a fiberglass post cemented with RelyX™ ARC.

Material And Methods: Eighty-four premolars were instrumented and divided into groups (n = 12) according to the sealer and the time of post cementation: Endofill (EN), Endosequence BC Sealer (BC), and AH Plus (AH) had immediately fiber post cementation; EN7, BC7, and AH7 had post cementation after 7 days; and control group (C) had fiber post cementation without endodontic sealer. Each post space of the root was cut into slices and submitted to push-out test.

Endodontic Management of Open Apex Teeth Using Lyophilized Collagen Sponge and MTA Cement: Report of Two Cases.

Teeth with open apices, such as in immature teeth or those with apical root resorption are clinical cases with difficult immediate resolution. With the use of mineral trioxide aggregate (MTA) in dentistry, it was possible to optimize the treatment time of these cases by immediate placement of apical plug and the root canal filling. However, some negative effects can occur if MTA is extruded beyond the apex.