Feedback from human posterior parietal cortex enables visuospatial category representations as early as primary visual cortex.

Introduction: Categorization is a fundamental cognitive process, whereby the brain assigns meaning to sensory stimuli. Previous studies have found category representations in prefrontal cortex and posterior parietal cortex (PPC). However, these higher-order areas lack the fine-scale spatial representations of early sensory areas, and it remains unclear what mechanisms enable flexible categorization based on fine-scale features.

DLGAP1 and NMDA receptor-associated postsynaptic density protein genes influence executive function in attention deficit hyperactivity disorder.

Objective: To explore the association of DLGAP1 gene with executive function (EF) in attention deficit hyperactivity disorder (ADHD) children.

Method: A total of 763 ADHD children and 140 healthy controls were enrolled. The difference of EF between ADHD and controls was analyzed using the analysis of covariance (ANCOVA), with IQ, sex, and age as covariates.