2 results match your criteria: "CAS Center for Excellence in Molecular Plant Sciences Chenshan Science Research Center[Affiliation]"

Functional evolution and diversification of CYP82D subfamily members have shaped flavonoid diversification in the genus Scutellaria.

Plant Commun

September 2024

The SATCM Key Laboratory for New Resources & Quality Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Department of Pharmacy, Second Affiliated Hospital of Navy Medical University, Shanghai 200003, China. Electronic address:

Flavonoids, the largest class of polyphenols, exhibit substantial structural and functional diversity, yet their evolutionary diversification and specialized functions remain largely unexplored. The genus Scutellaria is notable for its rich flavonoid diversity, particularly of 6/8-hydroxylated variants biosynthesized by the cytochrome P450 subfamily CYP82D. Our study analyzes metabolic differences between Scutellaria baicalensis and Scutellaria barbata, and the results suggest that CYP82Ds have acquired a broad range of catalytic functions over their evolution.

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Article Synopsis
  • * A genome-wide analysis identified 88 2ODD genes in S. baicalensis, organized into 25 clades, and functional studies revealed specific roles for two genes, Sb2ODD1 and Sb2ODD7, in flavonoid biosynthesis, with Sb2ODD1 active in roots and Sb2ODD7 expressed in flowers.
  • * The findings suggest
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