Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss.

The hair cycle is composed of four primary phases: anagen, catagen, telogen, and exogen. Anagen is a highly mitotic phase characterized by the production of a hair shaft from the hair follicle, whereas catagen and telogen describe regression and the resting phase of the follicle, respectively, ultimately resulting in hair shedding. While 9% of hair follicles reside in telogen at any time, a variety of factors promote anagen to telogen transition, including inflammation, hormones, stress, nutritional deficiency, poor sleep quality, and cellular division inhibiting medication.

Africana Digital Pedagogy: Cultural Exchange, Learning, and Innovation.

This project was created to illuminate the role and value of digital platforms for the Africana community. This research project was exploratory in that the primary researchers had an unclear idea of how the collected response provided by the participants would correlate and interact with the general hypothesis of Africana digital pedagogy (ADP). We surveyed 56 individuals from different segments of the global Africana communities for their opinions on their digital platform usage, as well as what they learn about themselves and their communities.

Skeletal Muscle Nuclei in Mice are not Post-mitotic.

The skeletal muscle research field generally accepts that nuclei in skeletal muscle fibers (ie, myonuclei) are post-mitotic and unable to proliferate. Because our deuterium oxide (DO) labeling studies showed DNA synthesis in skeletal muscle tissue, we hypothesized that resident myonuclei can replicate . To test this hypothesis, we used a mouse model that temporally labeled myonuclei with GFP followed by DO labeling during normal cage activity, functional overload, and with satellite cell ablation.

Gene amplification mutations originate prior to selective stress in Acinetobacter baylyi.

The controversial theory of adaptive amplification states gene amplification mutations are induced by selective environments where they are enriched due to the stress caused by growth restriction on unadapted cells. We tested this theory with three independent assays using an Acinetobacter baylyi model system that exclusively selects for cat gene amplification mutants. Our results demonstrate all cat gene amplification mutant colonies arise through a multistep process.

The Performance Diagnostic Checklist - Human Services: Guidance for Assessment Administration.

The Performance Diagnostic Checklist - Human Services (PDC-HS) is an assessment designed to assess the environmental variables contributing to employee performance concerns in human-service settings. Recent research has demonstrated that interventions indicated by the PDC-HS result in improved employee performance across several human-service settings and that the assessment has acceptable reliability and validity. Although PDC-HS-indicated interventions have been effective at increasing employee performance, there is a need for additional guidance when using the assessment given the limited nature of the original administration guidelines.

The Impact of Smartphone Use on Course Comprehension and Psychological Well-Being in the College Classroom.

The present study explores the impact of smartphone use on course comprehension and the psychological well-being of students during class. Students in four classes ( = 106) were assigned to either a control group or quasi-experimental group. Students in the quasi-experimental group were instructed to place their smartphones on the front desk upon entering the class, while the control group had no instructions regarding smartphone use.

Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study.

External and internal stressors have been found to adversely affect skin health and overall wellness. There is growing interest in the use of anti-inflammatory and antioxidant plant-derived ingredients, such as ashwagandha, saffron, l-theanine, and tocopherol, to mitigate the impact of these stressors. In this study, we evaluate the effectiveness of oral and topical products (InnerCalm and SuperCalm, respectively) that contain naturally derived ingredients on skin redness, skin pigmentation, sleep, and mood in healthy females with Fitzpatrick skin type 1−4 and self-perceived sensitive skin.

Enabling FAIR data in Earth and environmental science with community-centric (meta)data reporting formats.

Research can be more transparent and collaborative by using Findable, Accessible, Interoperable, and Reusable (FAIR) principles to publish Earth and environmental science data. Reporting formats-instructions, templates, and tools for consistently formatting data within a discipline-can help make data more accessible and reusable. However, the immense diversity of data types across Earth science disciplines makes development and adoption challenging.

Wildland-urban interface fire ashes as a major source of incidental nanomaterials.

Although metal and metalloid concentrations in wildfire ashes have been documented, the nature and concentrations of incidental nanomaterials (INMs) in wildland-urban interface (WUI) fire ashes have received considerably less attention. In this study, the total metal and metalloid concentrations of 57 vegetation, structural, and vehicle ashes and underlying soils collected at the WUI following the 2020 fire season in northern California - North Complex Fire and LNU Lightning Complex Fire - were determined using inductively coupled plasma-time of flight-mass spectrometry after microwave-assisted acid digestion. The concentrations of Ti, Zn, Cu, Ni, Pb, Sn, Sb, Co, Bi, Cr, Ba, As, Rb, and W are generally higher in structural/vehicle-derived ashes than in vegetation-derived ashes and soils.

Strengthen and Respect Each Thread.

Through a culturally grounded epistemology, this article provides mental health practitioners and researchers an overview of how generational trauma can impact the well-being of Black, Indigenous, Latinx, and other historically marginalized communities. Historically, deficit-based lenses frame the experiences of Black, Indigenous, and other People of Color (BIPOC). Discussion of white supremacy as a factor that creates divisiveness, discontinuity, and othering is necessary to understand mental healthcare for marginalized communities.

Bilingual Development in the Receptive and Expressive Domains: They Differ.

In bilingual children, more so than in monolingual children, comprehension abilities exceed production abilities. While this receptive-expressive gap in bilinguals has been well documented, little is known about its development. The present study tracked growth in the Spanish and English receptive and expressive vocabularies of 52 bilingual children from 4.

Type and Breadth of High School Extracurricular Activity Involvement and Postsecondary Psychosocial Well-Being among Diverse Youth.

Many youth experience declines in psychosocial well-being during the transition from high school to postsecondary. Hypothesizing that extracurricular activity involvement in high school functions as a resource factor, the current study examines type and breadth as predictors of psychosocial well-being one year postsecondary. The sample (N = 4070) consisted of students from diverse ethnic-racial and socio-economic status backgrounds (30% Latinx; 60% had a parent without a college degree; 47% cisgender female).

Comparative behavioral ecotoxicology of Inland Silverside larvae exposed to pyrethroids across a salinity gradient.

Pyrethroids, a class of commonly used insecticides, are frequently detected in aquatic environments, including estuaries. The influence that salinity has on organism physiology and the partitioning of hydrophobic chemicals, such as pyrethroids, has driven interest in how toxicity changes in saltwater compared to freshwater. Early life exposures in fish to pyrethroids cause toxicity at environmentally relevant concentrations, which can alter behavior.

Comparing imidacloprid, clothianidin, and azoxystrobin runoff from lettuce fields using a soil drench or treated seeds in the Salinas Valley, California.

Neonicotinoid insecticide use has increased over the last decade, including as agricultural seed treatments (application of chemical in a coating to the seed prior to planting). In California, multiple crops, including lettuce, can be grown using neonicotinoid treated seeds or receive a direct neonicotinoid soil application (drenching) at planting. Using research plots, this study compared pesticide runoff in four treatments: (1) imidacloprid seed treatment; (2) clothianidin seed treatment; (3) imidacloprid drench and an azoxystrobin seed treatment; and (4) a control with no pesticidal treatment.

Factors influencing terrestriality in primates of the Americas and Madagascar.

Among mammals, the order Primates is exceptional in having a high taxonomic richness in which the taxa are arboreal, semiterrestrial, or terrestrial. Although habitual terrestriality is pervasive among the apes and African and Asian monkeys (catarrhines), it is largely absent among monkeys of the Americas (platyrrhines), as well as galagos, lemurs, and lorises (strepsirrhines), which are mostly arboreal. Numerous ecological drivers and species-specific factors are suggested to set the conditions for an evolutionary shift from arboreality to terrestriality, and current environmental conditions may provide analogous scenarios to those transitional periods.

US county-level prevalence and spatial distribution of optimal birth outcomes 2018-2019.

A shift in focus towards healthy reproductive outcomes may reveal opportunities for novel interventions and strategies to promote optimal health. Using variables from the National Center for Health Statistics restricted use natality files, we calculated Empirical Bayes smoothed (EBS) rates of optimal birth for the all live births-both overall and by maternal race/ethnicity-by applying the smoothing tool in GeoDa version 1.18.

Identifying Patients for Self-Administration of Omalizumab.

Omalizumab, a recombinant anti-immunoglobulin E (IgE) monoclonal antibody, is indicated for moderate to severe allergic asthma, chronic spontaneous urticaria, and nasal polyps, and is approved for self-administration. However, specific guidance on identifying candidates with characteristics suitable for this type of administration is lacking. To help address this issue, this article provides practical considerations for the health care provider treating patients with omalizumab.

Personality Predictors of Prejudicial Attitudes, Willingness to Engage, and Actual Engagement in Consensual Non-Monogamy.

Personality variables, including sensation-seeking, interpersonal trust, avoidance of uncertainty, endorsement of social conformity, and love styles (Ludus, Eros, Pragma, Storge, Mania, and Agape), were examined as predictors of prejudicial attitudes toward individuals who practice polyamory and personal interest in engaging in consensual non-monogamy (CNM) among 1831 participants who completed anonymous surveys online. Personality characteristics were also compared between individuals who currently practice CNM (n = 67) and case-matched controls involved in monogamous relationships. As predicted, prejudicial attitudes and willingness to engage in CNM were positively and moderately correlated and there was substantial overlap in the predictors of both variables.

Complex developmental and transcriptional dynamics underlie pollinator-driven evolutionary transitions in nectar spur morphology in Aquilegia (columbine).

Premise: Determining the developmental programs underlying morphological variation is key to elucidating the evolutionary processes that generated the stunning biodiversity of the angiosperms. Here, we characterized the developmental and transcriptional dynamics of the elaborate petal nectar spur of Aquilegia (columbine) in species with contrasting pollination syndromes and spur morphologies.

Methods: We collected petal epidermal cell number and length data across four Aquilegia species, two with short, curved nectar spurs of the bee-pollination syndrome and two with long, straight spurs of the hummingbird-pollination syndrome.