21 results match your criteria: "CA(A.N.); and Dell Medical School[Affiliation]"

Article Synopsis
  • This study investigated the effect of mitral stenosis (MS) on outcomes in patients undergoing transcatheter aortic valve replacement (TAVR) with modern balloon-expandable valves, using data from over 327,000 patients across multiple centers.
  • It was found that while patients with severe MS initially had worse outcomes, when matched for similar characteristics, their 30-day outcomes were similar to those with mild or less MS, except for a higher rate of pacemaker implantation.
  • However, by three years post-TAVR, patients with severe MS showed a significantly higher mortality rate compared to those with mild or less MS, suggesting long-term risks associated with severe MS.
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Article Synopsis
  • * Most patients had drug-refractory VT, with a significant portion having low-voltage zones in the heart, particularly in the interventricular septum, indicating a specific substrate for VT.
  • * After an average follow-up of 32 months, 41% of patients experienced sustained VT/VF recurrence, but those achieving complete procedural success had a reduced risk of recurrence compared to those who did not.
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Transesophageal Echocardiography Following Left Atrial Appendage Electrical Isolation: Diagnostic Pitfalls and Clinical Implications.

Circ Arrhythm Electrophysiol

June 2022

Texas Cardiac Arrhythmia Institute, St David's Medical Center, Austin (C.G., J.E.S., Q.C., D.G.D., S.M., C.T., A.A.-A., M.A.B., J.D.B., G.J.G., R.P.H., P.M.H., L.D.B., A.N.).

Article Synopsis
  • Following electrical isolation of the left atrial appendage (LAA), assessing its mechanical function through transesophageal echocardiography (TEE) is crucial for deciding on the continuation of oral anticoagulation in atrial fibrillation patients.
  • A study of 160 TEE exams revealed a 36% diagnostic discrepancy in LAA dysfunction, mostly misclassifying a normal function despite reduced contraction, particularly due to misinterpretation of passive flows.
  • This underdiagnosis significantly raised the risk of cerebrovascular events in patients who stopped anticoagulation, highlighting the need for careful TEE evaluation by experienced operators.
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Background: No completed trials have compared carotid artery stenting (CAS) to medical therapy (MT). We examined the effectiveness of CAS compared with MT in patients with asymptomatic carotid stenosis.

Methods: We conducted a retrospective cohort study of 219 979 Veterans ≥65 years who received carotid imaging for asymptomatic carotid stenosis between 2005 and 2009 in the US Veterans Health Administration.

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Recovery of Conduction Following High-Power Short-Duration Ablation in Patients With Atrial Fibrillation: A Single-Center Experience.

Circ Arrhythm Electrophysiol

October 2021

Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin (S.M., C.T., D.G.D.R., C.G., B.M., A.Q.M., A.A.-A., J.D.B., M.B., G.J.G., R.H., L.D.B., A.N.).

[Figure: see text].

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Background: Interventional therapies aiming at excluding the left atrial appendage (LAA) from systemic circulation have been established as a valid alternative to oral anticoagulation in patients at high thromboembolic risk. However, their efficacy on stroke prophylaxis may be compromised owing to incomplete LAA closure. Additionally, the need for an alternative thromboembolic prevention may remain unmet in patients with contraindications to oral anticoagulation whose appendage anatomy is unsuitable for some conventional devices commercially available.

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Background: The comparative effectiveness of non-vitamin K antagonist oral anticoagulants (NOACs) is uncertain, as they have not been compared directly in randomized trials. Previous observational comparisons of NOACs are likely to be biased by unmeasured confounders. We sought to compare the efficacy and safety of rivaroxaban and apixaban for stroke prevention in patients with atrial fibrillation (AF), using practice variation in preference for NOAC as an instrumental variable.

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Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation.

Circ Arrhythm Electrophysiol

March 2020

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Program in Medical and Population Genetics, Cambridge, MA (C.R., P.E., S.L.).

Background: Ablation is a widely used therapy for atrial fibrillation (AF); however, arrhythmia recurrence and repeat procedures are common. Studies examining surrogate markers of genetic susceptibility to AF, such as family history and individual AF susceptibility alleles, suggest these may be associated with recurrence outcomes. Accordingly, the aim of this study was to test the association between AF genetic susceptibility and recurrence after ablation using a comprehensive polygenic risk score for AF.

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Long-Term Outcome of Pulmonary Vein Isolation With and Without Focal Impulse and Rotor Modulation Mapping: Insights From a Meta-Analysis.

Circ Arrhythm Electrophysiol

March 2018

From the Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin (S.M., P.M., C.T., C.G., D.G.D.R., L.D.B., A.N.); Dell Medical School, Austin, TX (S.M., A.N.); Electrophysiology and Arrhythmia Services, California Pacific Medical Center, San Francisco (A.N.); MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH (A.N.); and Division of Cardiology, Stanford University, CA (A.N.).

Background: This meta-analysis systematically evaluated the outcome of pulmonary vein isolation (PVI) with and without focal impulse and rotor modulation (FIRM) ablation in patients with atrial fibrillation.

Methods And Results: Extensive literature search was performed for studies reporting outcomes of PVI alone and PVI+FIRM procedures. For PVI alone, only randomized trials conducted in the past 3 years reporting single-procedure off-antiarrhythmic drugs success rate at ≥12-month follow-up were included.

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Response by Di Biase et al to Letter Regarding Article, "Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device: Results From the AATAC Multicenter Randomized Trial".

Circulation

September 2016

From Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin (L.D.B., P.M., S.M., P.S., C.T., J.S., R.H., J.D.B., A.N.); Albert Einstein College of Medicine, at Montefiore Hospital, New York, NY (L.D.B.); Department of Biomedical Engineering, University of Texas, Austin (L.D.B., A.N.); Department of Cardiology, University of Foggia, Italy (L.D.B.); University of Kansas, Kansas City (D.L., M.R.); Hôpital Cardiologique du Haut Lévêque, Université Victor-Segalen Bordeaux, France (P.J., M.H.); Ospedale dell'Angelo, Mestre Venice, Italy (S.T., A.R.); Cardiac Arrhythmia Research Centre, Centro Cardiologico Monzino IRCCS, Milan, Italy (A.D.R., M.C., C.T.); University of Sacred Heart, Rome, Italy (G.P., M.L.N.); Akron General Hospital, Ohio (R.S.); Department of Cardiology, Na Homolce Hospital, Roentgenova 2, Prague, Czech Republic (P.N.); California Pacific Medical Center, San Francisco (S.B., R.H., S.H., A.N.); University of Tor Vergata, Rome, Italy (G.F.); Division of Cardiology, Stanford University, Palo Alto, CA (A.N.); Case Western Reserve University, Cleveland, OH (A.N.); Scripps Clinic, San Diego, CA(A.N.); and Dell Medical School, Austin, TX (A.N.).

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Left Atrial Appendage After Electrical Isolation: To Occlude or Not To Occlude, That Is the Question.

Circ Arrhythm Electrophysiol

July 2016

From the Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (L.D.B.); Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin (L.D.B., A.N.); Department of Biomedical Engineering, University of Texas, Austin (L.D.B.); Department of Cardiology, University of Foggia, Italy (L.D.B.); Division of Cardiology, Stanford University, Palo Alto, CA (A.N.); Section of Electrophysiology, Case Western Reserve University, Cleveland, OH (A.N.); Section of Electrophysiology, Scripps Clinic, San Diego, CA (A.N.); Dell Medical School, Austin, TX (A.N.); and California Pacific Medical Center, San Francisco (A.N.).

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Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device: Results From the AATAC Multicenter Randomized Trial.

Circulation

April 2016

From Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin (L.D.B., P.M., S.M., P.S., C.T., J.S., R.H., J.D.B., A.N.); Albert Einstein College of Medicine, at Montefiore Hospital, New York, NY (L.D.B.); Department of Biomedical Engineering, University of Texas, Austin (L.D.B., A.N.); Department of Cardiology, University of Foggia, Italy (L.D.B.); University of Kansas, Kansas City (D.L., M.R.); Hôpital Cardiologique du Haut Lévêque, Université Victor-Segalen Bordeaux, France (P.J., M.H.); Ospedale dell'Angelo, Mestre Venice, Italy (S.T., A.R.); Cardiac Arrhythmia Research Centre, Centro Cardiologico Monzino IRCCS, Milan, Italy (A.D.R., M.C., C.T.); University of Sacred Heart, Rome, Italy (G.P., M.L.N.); Akron General Hospital, OH (R.S.); Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic (P.N.); California Pacific Medical Center, San Francisco (S.B., R.H., S.H., A.N.); University of Tor Vergata, Rome, Italy (G.F.); Division of Cardiology, Stanford University, Palo Alto, CA (A.N.); Case Western Reserve University, Cleveland, OH (A.N.); Scripps Clinic, San Diego, CA (A.N.); and Dell Medical School, Austin, TX (A.N.).

Background: Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure is unknown.

Methods And Results: This was an open-label, randomized, parallel-group, multicenter study. Patients with persistent AF, dual-chamber implantable cardioverter defibrillator or cardiac resynchronization therapy defibrillator, New York Heart Association II to III, and left ventricular ejection fraction <40% within the past 6 months were randomly assigned (1:1 ratio) to undergo CA for AF (group 1, n=102) or receive AMIO (group 2, n=101).

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Left Atrial Appendage Occlusion Device and Novel Oral Anticoagulants Versus Warfarin for Stroke Prevention in Nonvalvular Atrial Fibrillation: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Circ Arrhythm Electrophysiol

October 2015

From the Department of Medicine, Division of Cardiology, Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY (D.F.B., P.V., N.C., D.M., E.B., E.M., P.A., K.F., J.G., S.G.K., A.K., E.P., N.G., J.R., J.F., M.G., L.D.B.); Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin (A.N., L.D.B.); Department of Biomedical Engineering, University of Texas, Austin (A.N., L.D.B.); Division of Cardiology, Stanford University, Palo Alto, CA (A.N.); Division of Cardiovascular Medicine, Case Western Reserve University, Cleveland, OH (A.N.); Interventional Electrophysiology, Scripps Clinic, San Diego, CA (A.N.); Dell Medical School, Austin, TX (A.N.); California Pacific Medical Center, San Francisco (A.N.); and Department of Cardiology, University of Foggia, Foggia, Italy (L.D.B.).

Background: Nonvalvular atrial fibrillation is the most common arrhythmia. Patients with nonvalvular atrial fibrillation are at increased risk of stroke; therefore, we evaluated the efficacy and safety of different approaches to prevent this major complication.

Methods And Results: We conducted electronic database searches of phase III randomized controlled trials.

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Feasibility of combined unipolar and bipolar voltage maps to improve sensitivity of endomyocardial biopsy.

Circ Arrhythm Electrophysiol

June 2015

From the Cardiac Arrhythmia Research Centre, Milan, Italy (M.C., F.P., A.D.R., C.C., G.A.-M., E.R., S.R., G.F., F.T., C.T.); Centro Cardiologico Monzino IRCCS, Milan, Italy (E.S., M.G.); Cardiovascular and Neurological Department, San Donato Hospital, Arezzo, Italy (P.N., M.P., A.C., L.B.); Department of Experimental Medicine, Sapienza University, Rome, Italy (G.D.A.,); Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin (P.S., L.D.B., A.N.); Department of Cardiology, University of Foggia, Foggia, Italy (P.S., L.D.B.); Albert Einstein College of Medicine at Montefiore Hospital, New York City (L.D.B.); Department of Biomedical Engineering, University of Texas, Austin (L.D.B., A.N.); Division of Cardiology, Stanford University, Palo Alto, CA (A.N.); Case Western Reserve University, Cleveland, OH (A.N.); Interventional Electrophysiology, Scripps Clinic, San Diego, CA (A.N.); and EP Services, California Pacific Medical Center, San Francisco (A.N.).

Background: Endomyocardial biopsy (EMB) has a low sensitivity. Electroanatomic voltage mapping (EVM) is effective in guiding EMB thanks to its ability in identifying and locating low-voltage regions. The analysis of unipolar EVM can correlate with epicardial pathological involvement.

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Effect of catheter ablation and periprocedural anticoagulation regimen on the clinical course of migraine in atrial fibrillation patients with or without pre-existent migraine: results from a prospective study.

Circ Arrhythm Electrophysiol

April 2015

From the Department of Electrophysiology, Texas Cardiac Arrhythmia Institute, St. David's Medical Center (S.M., P.M., J.N.R., L.D.B., C.T., P.S., R.B., D.C., J.D.B., J.G.G., R.H., J.E.S., S.B., P.M.H., J.Z., A.A.-A., A.N.), Department of Biology, College of Natural Sciences (S.M.), and Department of Biomedical Engineering (L.D.B., R.X.Y., A.N.), University of Texas, Austin; Department of Cardiology, University of Foggia, Foggia, Italy (L.D.B., P.S.); Department of Cardiology, Albert Einstein College of Medicine at Montefiore Hospital, Bronx, NY (L.D.B.); Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China (R.B.); Department of Electrophysiology, California Pacific Medical Center, San Francisco (A.N.); Division of Cardiology, Department of Cardiology, Stanford University, CA (A.N.); Department of Interventional Electrophysiology, Scripps Clinic, San Diego, CA (A.N.); and Department of Medicine, Case Western Reserve University, Cleveland, OH (A.N.).

Background: We examined the influence of catheter ablation and periprocedural anticoagulation regimen on trajectory of migraine in atrial fibrillation patients with or without migraine history.

Methods And Results: Forty patients with (group 1: 64 ± 8 years; men 78%) and 85 (group 2: 61 ± 10 years; men 73%) without migraine history undergoing atrial fibrillation-ablation were enrolled. Migraine status and quality of life were evaluated using standardized questionnaires.

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Periprocedural stroke and bleeding complications in patients undergoing catheter ablation of atrial fibrillation with different anticoagulation management: results from the Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation (COMPARE) randomized trial.

Circulation

June 2014

From the Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin (L.D.B., J.D.B., P.S., P.M., J.E.S., R. Horton, G.J.G., J.Z., B.R., S.M., A.N.); Albert Einstein College of Medicine, Montefiore Hospital, New York, NY (L.D.B.); Department of Biomedical Engineering, University of Texas, Austin (L.D.B., A.N.); Department of Cardiology, University of Foggia, Foggia, Italy (L.D.B., P.S.); Ospedale dell'Angelo, Mestre Venice, Italy (S.T., A.R.); University of Kansas, Kansas City (D.L., M.R.); California Pacific Medical Center, San Francisco (S.H., R. Hongo, S.B., A.N.); University of Kentucky, Lexington (C.S.E.); University of Tor Vergata, Rome, Italy (G. Forleo); University of Sacred Heart, Rome, Italy (G.P., M.L.N.); Cardiac Arrhythmia Research Centre, Centro Cardiologico Monzino IRCCS, Milan, Italy (A.D.R., M.C., G. Fassini, C.T.); Akron General Hospital, Akron, OH (R.A.S.); Division of Cardiology, Stanford University, CA (A.N.); Case Western Reserve University, Cleveland, OH (A.N.); and Interventional Electrophysiology, Scripps Clinic, La Jolla, CA (A.N.).

Background: Periprocedural thromboembolic and hemorrhagic events are worrisome complications of catheter ablation for atrial fibrillation (AF). The periprocedural anticoagulation management could play a role in the incidence of these complications. Although ablation procedures performed without warfarin discontinuation seem to be associated with lower thromboembolic risk, no randomized study exists.

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Stroke or transient ischemic attack in patients with transvenous pacemaker or defibrillator and echocardiographically detected patent foramen ovale.

Circulation

September 2013

Department of Internal Medicine, Mayo Clinic, Rochester, MN (C.V.D, D.C.D, C.A.A, V.R.V.); Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (C.V.D, P.A.F., M.J.A, S.J.A.); Division of Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA (A.N.); Mayo Medical School, Rochester, MN (N.A.P.); Mayo Graduate School of Medicine Visiting Scholars Program, Mayo Clinic, Rochester, MN (S.B.); Department of Statistics, Mayo Clinic, Rochester, MN (J.P.S., D.O.H.); Department of Pediatrics and Adolescent Medicine Mayo Clinic, Rochester, MN (M.J.A., S.J.A.); and Department of Neurology, Mayo Clinic, Rochester, MN (A.A.R.).

Background: A patent foramen ovale (PFO) may permit arterial embolization of thrombi that accumulate on the leads of cardiac implantable electronic devices in the right-sided cardiac chambers. We sought to determine whether a PFO increases the risk of stroke/transient ischemic attack (TIA) in patients with endocardial leads.

Methods And Results: We retrospectively evaluated all patients who had endocardial leads implanted between January 1, 2000, and October 25, 2010, at Mayo Clinic Rochester.

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