Metabolic complications of obesity.

Obesity is a risk factor for several metabolic complications, with insulin resistance being the common denominator in these conditions. Impaired blood glucose regulation is one of the most important of these complications, and includes type 2 diabetes mellitus (T2DM), prediabetes, and gestational diabetes. Metabolic syndrome describes a constellation of features including insulin resistance, hypertension, dyslipidemia, and abdominal obesity.