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Usefulness of diagnostic indices comprising clinical, sonographic, and biomarker data for discriminating benign from malignant ovarian masses.

J Ultrasound Med

February 2015

Department of Gynecological Oncology, Gdynia Oncology Center, Gdynia, Poland (M.S., M.D.); Information Technology Department, Business Consulting Center, Gdansk, Poland (K.R.); and Department of Gynecology and Gynecological Oncology, Kliniken-Essen-Mitte, Essen, Germany (J.P.G.).

The objective of this study was to review the accuracy of indices combining several diagnostic variables, in comparison to other models, sonography alone, and biomarker assays, for predicting benign or malignant ovarian lesions. Different single modalities were reviewed. The most useful complex models were International Ovarian Tumor Analysis (IOTA) sonographic logistic regression model 2 (area under the curve, 0.

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