4,905 results match your criteria: "Bursa Yueksek İhtisas Hospital[Affiliation]"

Objective: We aimed to investigate the relationship between advanced glycation end product (AGE) levels in patients with saphenous vein graft (SVG) failure and in patients without SVG failure.

Subjects And Methods: In our study, 55 patients with a history of previous coronary artery bypass grafting (CABG) surgery, who subsequently underwent coronary angiography for any reason and were found to have either SVG occlusion or significant lesions, were included as study patients. Additionally, 55 patients who have had CABG surgery without SVG failure for at least 1 year served as the control group.

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Perioperative and postoperative effects of hydrostatic pressure applied to the dura mater on central nervous system in unilateral biportal endoscopic spine surgery.

Neurosciences (Riyadh)

October 2024

From the Departments of Anaesthesiology and İntensive Care (Çevikkalp, Efe,), Departments Of Spine Surgery (Aygün), Bursa Private Medicana Hospital, and from the Departments Of Orthopedics and Traumatology (Yıldız), Bursa Private Atakent Hospital, Bursa, Turkey.

Article Synopsis
  • The study aims to assess how applying pressure to the dura mater affects optic nerve sheath diameter (ONSD) and investigates postoperative complications.
  • Conducted at Private Medicabil Hospital, measurements of ONSD using ultrasound were taken at five different times during surgeries from January to June 2022.
  • Results showed that ONSD increased significantly when pressure was applied, with specific values indicating a high sensitivity and specificity for identifying potential complications, suggesting that monitoring ONSD can help lessen risks to the central nervous system.
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Background: Anticoagulation during extracorporeal membrane oxygenation (ECMO) might still lead to severe bleeding complications. Heparin is the most frequently used anticoagulant, but novel drugs could be promising. Argatroban is a new alternative to heparin.

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Article Synopsis
  • Knee osteoarthritis (KOA) is a degenerative disease affecting the knee, leading many patients to require total knee arthroplasty (TKA) when non-surgical treatments fail.
  • A study involving 50 patients assessed MRI features and their correlations with functional scores, revealing high prevalence of cartilage lesions and osteophytes among participants.
  • Key findings indicated a consistent MRI pattern for TKA candidates, highlighting significant lesions in multiple knee compartments and suggesting the severity of KOA based on specific imaging characteristics.
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The epithelial barrier theory and its associated diseases.

Allergy

December 2024

Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.

The prevalence of many chronic noncommunicable diseases has been steadily rising over the past six decades. During this time, over 350,000 new chemical substances have been introduced to the lives of humans. In recent years, the epithelial barrier theory came to light explaining the growing prevalence and exacerbations of these diseases worldwide.

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Background: Diabetes is a global problem. Diabetes nurses, in particular, take great responsibility in reducing and controlling the fears of individuals using insulin and increasing their capacity to tolerate discomfort.

Aim: This study was conducted to examine the effects of the capacity to tolerate discomfort on the fear of self-injection and the status of testing blood glucose levels in patients with type 1 and type 2 diabetes using insulin.

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Article Synopsis
  • The study investigates the fracture strength of various CAD/CAM restorations for lower first molars with significant crown damage, including post-core full-contour crowns, composite resin cores, and endocrowns.
  • Results show that the control group exhibited the highest fracture strength, while the core full-contour crown group had the lowest, indicating varying effectiveness among the restoration types.
  • The research highlights the importance of using CAD/CAM technology in dental practices to improve restorative options and patient outcomes, particularly in minimizing the risk of tooth fractures.
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Background: Pseudoaneurysm of the cystic artery is very rare. It usually presents with rupture and hemorrhagic shock, which may be life-threatening. Ultrasonography and contrast-enhanced tomography can be used for the diagnosis.

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Importance: Infectious bursal disease (IBD) is an important viral poultry disease that vaccination can control.

Objective: This study examined the immune protection of immune-complex (Vaccine A) and attenuated live (Vaccine B) IBD vaccines in specific-pathogen-free (SPF) chickens against a novel Malaysian variant IBD virus (vaIBDV) challenge.

Methods: One-day-old (n =75) SPF chickens were divided randomly into the following three groups of 25 chicks each: Control, Vaccine A, and Vaccine B groups.

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The dataset presents a 43 year-long reanalysis of pollen seasons for three major allergenic genera of trees in Europe: alder (Alnus), birch (Betula), and olive (Olea). Driven by the meteorological reanalysis ERA5, the atmospheric composition model SILAM predicted the flowering period and calculated the Europe-wide dispersion pattern of pollen for the years 1980-2022. The model applied an extended 4-dimensional variational data assimilation of in-situ observations of aerobiological networks in 34 European countries to reproduce the inter-annual variability and trends of pollen production and distribution.

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Article Synopsis
  • The study analyzed radiological and anatomical measurements in 23 patients aged 18-45 with medial osteochondral lesions of the talus (OLT) who had no trauma history, comparing them to a control group of 27 individuals.
  • Significant findings included a correlation between medial OLT and decreased talar declination angle (P<0.001) and Meary-Tomeno's angle (P=0.003), suggesting these angles may contribute to OLT development.
  • The research concludes that lower positions of the talus in relation to the ground and first metatarsus might be a key factor in the formation of medial OLT in non-traumatic patients.
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Background: We evaluated the efficacy of different immunosuppressive regimens in patients with primary membranous nephropathy in a large national cohort.

Methods: In this registry study, 558 patients from 47 centers who were treated with at least one immunosuppressive agent and had adequate follow-up data were included. Primary outcome was defined as complete (CR) or partial remission (PR).

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Our knowledge of the factors related to parenting styles affecting adherence to diet in children with celiac diseases (CDs) and the association between psychiatric difficulties and diet compliance is largely based on limited data. Therefore, our work aims to examine primarily coexisting psychiatric difficulties in children with CD and raising attitudes of their parents and secondarily the relationship among adherence to treatment, psychiatric difficulties, and parental attitudes. Children aged 4-12 years (n = 42) who have been followed up with the diagnosis of CD in a Paediatric Gastroenterology Outpatient Clinic were compared with those of healthy controls (n = 31).

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Patient Factors Associated with Access to Outpatient Pediatric General Surgical Care in a Rural State.

J Pediatr Surg

January 2025

Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Division of Pediatric Surgery, Arkansas Children's Hospital, Little Rock, AR, USA.

Background: We sought to understand factors impacting timely access to outpatient pediatric general surgical care in a largely rural state.

Methods: We conducted a multi-site retrospective cohort study, evaluating patients <18 years referred for outpatient pediatric general surgical evaluation from 11/1/2017-7/31/2022. Outcomes included obtaining an appointment, completing an appointment, and undergoing an operation.

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Real-world data on Empagliflozin and Dapagliflozin use in patients with HEART failure: The RED-HEART study.

ESC Heart Fail

February 2025

Department of Cardiology, İzmir University of Economics, Faculty of Medicine, Medical Point Hospital, İzmir, Türkiye.

Aims: We aimed to determine the use of sodium-glucose cotransporter 2 inhibitors (SGLT2is) and to identify clinical factors associated with their use in patients with heart failure (HF) in a real-life setting.

Methods: Real-world data on Empagliflozin and Dapagliflozin use in patients with HEART failure: The RED-HEART study is a multicentre, cross-sectional and observational study that included HF patients in the outpatient setting regardless of ejection fraction from 19 cardiology centres between August 2023 and December 2023.

Results: The study population consisted of 1923 patients with HF, predominantly men (61.

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Chronic lumbar facet pain is commonly treated with fluoroscopy-guided facet medial branch blocks (FMBBs). However, the associated radiation exposure of both patients and clinicians is a growing concern. This study aimed to compare radiation doses and fluoroscopy times between two techniques, i.

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The Role of Thalidomide and Its Analogs in the Treatment of Hereditary Hemorrhagic Telangiectasia: A Systematic Review.

J Clin Med

September 2024

Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Trakya University, 22030 Edirne, Turkey.

Article Synopsis
  • Hereditary hemorrhagic telangiectasia (HHT) is a genetic condition characterized by irregular blood vessel formations that can lead to excessive bleeding, and treatments using antiangiogenic and immunomodulatory drugs like thalidomide show promise in managing the disease.
  • A systematic review evaluated 53 articles, ultimately including 15 studies on thalidomide, which was found to be effective in reducing symptoms like bleeding, but with a high adverse event rate of up to 85%.
  • While lenalidomide and pomalidomide were explored with some success, more research is needed to determine the best treatment approach regarding timing, dosage, and overall therapy strategies for HHT.
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Article Synopsis
  • * Among 106 patients, 83 had CN, and those who had the surgery could continue their nivolumab treatment for longer (14.5 months) compared to those who didn't have the surgery (6.7 months).
  • * Overall survival was better for patients with CN (22.9 months) compared to those without it (8.1 months), but the surgery and certain medical scores were important factors for how long they lived.
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Cystic lymphangioma is a benign lymphatic malformation that primarily affects children, with rare occurrences in adults. These malformations are most commonly found in the head and neck region, though their presence in the abdominal cavity is infrequent. In this report, we present the case of 71-year-old women with a cystic lymphangioma located in the omental bursa.

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Erectile dysfunction (ED) is one of the most common complaints in the male sexual health field, with a multifactorial etiology yet to be fully elucidated. Nucleobindin 2 (NUCB2)/nesfatin-1, known for its regulatory role in food intake, can also regulate the vascular, neural and hormonal systems, all of which are of great importance in the etiology of ED. The present study included 43 men with ED and 40 healthy individuals without ED.

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Article Synopsis
  • * The researchers examined 98 knees with early KOA, finding key findings such as synovial hyperplasia, knee joint effusion, and medial meniscus tears using ultrasound.
  • * Results showed correlations between these findings and various KOOS subscales, with synovial hyperplasia and medial meniscus extrusion in upright position being particularly associated with quality of life and other symptoms.
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  • Millions are affected by natural disasters annually, leading to serious medical issues like crush syndrome, which often results in acute kidney injury tied to high mortality rates.
  • This study analyzed data from 1024 patients with crush syndrome after the February 2023 earthquakes in Kahramanmaras, focusing on their treatment and outcomes in Turkish hospitals.
  • The findings revealed high rates of acute kidney injury and hemodialysis treatment, with a 9.8% in-hospital mortality rate, highlighting the urgent need for improved emergency response training and protocols for managing kidney health in disaster scenarios.
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  • * A study in Turkey examined the responses of 17 patients with solid tumors and NTRK fusions who received entrectinib, revealing a median age of 42 years and various types of cancer, with NTRK1 and NTRK3 being the most common gene rearrangements.
  • * Results showed a 35.3% objective response rate with side effects leading to dosage reductions in four patients; the median overall survival was 20.8 months
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