271 results match your criteria: "Burrell College of Osteopathic Medicine[Affiliation]"

Stiff person spectrum disorder is a disease that involves a host of conditions that are associated with glutamic acid decarboxylase 65-kilodalton isoform autoantibodies. These conditions may include diabetes mellitus type 1, pernicious anemia, autoimmune leukoencephalopathy, cerebellar ataxia, and stiff-person syndrome. Clinical recognition and diagnosis of stiff person spectrum disorder are important early, as immunologic treatment options showing reliable efficacy in slowing disease progression are available.

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This case report details the presentation, diagnosis, and management of a newborn Native American male with non-Herlitz junctional epidermolysis bullosa (JEB), a rare diagnosis specifically in the Native American population. Genetic analysis revealed a homozygous mutation in the COL17A1 gene. The management involved multidisciplinary care and highlighted the challenges in treatment, including pain management, wound care, and ethical considerations surrounding adoption within Indigenous communities.

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The long-term effects of low-dose radiation exposure are a topic that has been lightly touched on in medical literature. We present a case of a 66-year-old male, who grew up near uranium mines, with several pathologies that are believed to be well explained by his chronic exposure to low-dose radiation. We postulate that screening for etiologies with known associations with radiation may help avoid long-term complications in at-risk populations.

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Acupuncture, an increasingly popular alternative medical therapy, has heightened the demand for information on its safety profile. This is a case report involving a 28-year-old female who presented with intense right-sided chest pain and breathlessness after an acupuncture session where needles were inserted into her chest wall. The immediate medical evaluation revealed a tension pneumothorax with radiographic evidence of a mediastinal shift, compelling, urgent intervention via chest tube insertion.

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Article Synopsis
  • Facial bone fractures are less common in women than in men in the U.S., yet there is limited knowledge about the specifics of women who experience these injuries.
  • The study aims to analyze the characteristics, types, and costs of emergency care for women with facial fractures using 2019 data from the National Emergency Department Sample.
  • Findings show that while women represent 37% of facial fractures in emergency settings, they tend to be older, more likely to be on Medicare, and have lower medical costs compared to men, but the total financial burden for their care is significant at $1.6 billion.
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Objectives: We evaluated the effects of four treatments for pathogen inactivation in bone tissue (ethanol storage, formalin fixation, gamma irradiation, and heat treatment via autoclave) on stiffness and anisotropy values in bone samples.

Materials And Methods: Cortical bone samples from the humerus of 14 bovine specimens were subjected to Knoop microindentation analysis in longitudinal and transverse planes of section and four indenter orientations within each section. From each specimen, individual samples were assigned to one of five treatment conditions: 50% ethanol-saline solution, formalin immersion, gamma irradiation, autoclave, and buffered saline (controls).

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Background: As pediatric hospitals continue to grow in innovation, it is important to create a standardized metric to measure this growth and create a network to encourage further innovation. We worked to classify all pediatric hospitals on a scale of innovation with the goal of encouraging collaboration that can lead to more overall innovation.

Methods: All pediatric hospitals worldwide were ranked on a scale of innovation from 1 to 3, with 1 being the most innovative, or "established," and 3 being the least innovative, or "nascent.

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We present a man in his 60s with a dorsal thoracic arachnoid web spanning levels T6-T8. The patient presented with gait abnormalities, severe neuropathic lower back pain and mild urinary incontinence without sensory deficits. He underwent laminectomy with arachnoid web fenestration.

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Regenerative medicine leverages the body's inherent regenerative capabilities to repair damaged tissues and address organ dysfunction. In orthopedics, this approach includes a variety of treatments collectively known as orthoregeneration, encompassing modalities such as prolotherapy, extracorporeal shockwave therapy, pulsed electromagnetic field therapy, therapeutic ultrasound, and photobiomodulation therapy, and orthobiologics like platelet-rich plasma and cell-based therapies. These minimally invasive techniques are becoming prominent due to their potential for fewer complications in orthopedic surgery.

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Article Synopsis
  • * This case study follows an 80-year-old man with several health problems, documenting his treatment over six visits and the challenges faced due to infections by MRSA and Group B Streptococcus.
  • * The patient improved with a tailored treatment of topical and systemic steroids, highlighting the need for accurate diagnosis and adaptable treatment strategies in managing NDDH amidst other health conditions.
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Extracellular vesicles (EVs) are membrane-bound exosomes secreted into the apoplast. Two distinct populations of EVs have been described in Arabidopsis: PEN1-associated and TET8-associated. We previously noted early leaf senescence in the single and double mutant.

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There is conflicting information in the medical literature regarding hemolysis, elevated liver enzymes, low platelet count syndrome (HELLP) and preeclampsia and whether they are subsets of a single disease or distinct complications of pregnancy. In numerous places, HELLP is described as a severe form or later stage of preeclampsia. However, a detailed medical literature search utilizing NCBI, PubMed, and Elicit: The AI Research Assistant clearly demonstrates that HELLP and preeclampsia are distinct diseases.

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Background: Breast cancer (BC) affects racial and ethnic groups differently, leading to disparities in clinical presentation and outcomes. It is unclear how Hispanic ethnicity affects BC outcomes based on geographic location and proximity to the United States (U.S.

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Recently, Yohe and Krell (The Anatomical Record, vol. 306:2765-2780) lamented the incongruence between genetics and morphology in the vomeronasal system of bats. Here, we studied 105 bat species from 19 families using histology, iodine-enhanced computed tomography (CT), and/or micro-CT.

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Cardiovascular diseases (CVDs) account for nearly half of chronic kidney disease (CKD)-related deaths. Hypomagnesemia has been associated with various cardiovascular conditions and predicts a decline in renal function leading to end-stage renal disease (ESRD). The objective of this review is to delve into and discuss the significance of magnesium (Mg) in cardiovascular and renal functions, the clinical consequences of hypomagnesemia on CVD and CKD, and the benefits of Mg supplementation in managing CVD and CKD.

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Fecal microbiota transplantation is an evidence-based therapeutic option for recurrent infection, involving the transfer of healthy donor fecal material to restore gut microbial balance. Despite meticulous donor screening, , a prevalent cause of bacterial gastroenteritis, is not routinely tested, potentially impacting fecal microbiota transplant safety. We present a case of a female with recurrent infection treated with fecal microbiota transplantation, complicated by a subsequent infection.

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Pituitary apoplexy is a result of rapid enlargement of the pituitary, due to episodes of hyperplasia, which outpaces vascular development resulting in ischemia and potential infarction of pituitary tissue. This can present in several different ways from asymptomatic to hormonal deficiencies. Here we present a case of spontaneous reduction of a non-functioning pituitary mass, likely due to apoplexy, in which the mass went from compromising the optic chiasm to complete reduction and relief of the optic chiasm.

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Article Synopsis
  • Granulomatosis with polyangiitis (GPA) is a rare type of vasculitis that mainly affects small and medium blood vessels, characterized by granulomas particularly in the upper respiratory tract and kidneys.
  • A 54-year-old woman presented with symptoms leading to the discovery of GPA, despite being seronegative for common antibodies like ANCA; her lung lesions were identified through imaging and biopsy.
  • The patient underwent treatment with intravenous rituximab for six months after diagnoses, which revealed necrotizing granulomatous inflammation.
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Context: Fryette's mechanics is taught as a simplistic model of coupled vertebral movement, fundamental in osteopathic practice. This study seeks to better understand the likelihood of Fryette's model by calculating vertebral orientation in computed tomography (CT) scans. Given previous findings of low angular coupled movements during overall spinal motion, static calculations provide a unique perspective on the likelihood of Fryette's mechanics.

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