[ADULTS NEUROGENESIS AS A RESERVE FOR HEALTH PRESERVATION].

The article presents scientific evidence that new neurons from progenitor cells throughout life in almost all animals with a nervous system are an integral component of neuronal ontogenesis and plasticity.It has been shown that there are neural stem cells in the brain that give rise to adult neurogenesis, occurring primarily in the dentate gyrus, a subregion of the hippocampus important for learning, memory, and emotion. With age, there is a decrease in adult neurogenesis, which is associated with a decrease in cognitive functions.

Microminiaturization of Multichannel Multifrequency Radiographs.

Due to the COVID-19 epidemic, the challenge of introducing methods for investigating patients reducing or eliminating the probability of infection of medical staff is currently relevant. This article provides an analytical review of new technological approaches to organizing the work of medical personnel in carrying out auscultation of patients with COVID-19. The development and approval of such technologies is shown to have started around the world.

[THE ISSUE OF THE IMPACT OF RADIOACTIVE SUBSTANCES ON PUBLIC HEALTH AND COUNTERMEASURES FOR RADIATION EXPOSURE AS A GLOBAL PROBLEM].

The widespread use in today's world of radioactive sources d in energy, medicine, engineering and construction, for contaminant tracking and food sterilization increases the likelihood of accidental exposure. The use of ionizing radiation and radioactive elements can directly or indirectly cause life-threatening complications, such as oncopathology, radiation burns, and impaired immunity. Pollution of the environment with radioactive elements and depletion of the ozone layer also contribute to an increase in the level of radiation exposure.

[Use of urethral stents for urethral strictures].

Urethral stents have been popular in urology since the early 1980s and are used in the treatment of urethral stricture. The literature review presents data on the introduction into urological practice and the use of urethral stents in urethral strictures.

Monte-Carlo calculation of output correction factors for ionization chambers, solid-state detectors, and EBT3 film in small fields of high-energy photons.

High-energy accelerators are often used in oncological practice, but the information on the small-field dosimetry for the photon beams with nominal energy above 10 MV is limited. The goal of the present work was to determine the values of the output correction factor ( ) for solid-state detectors (Diode E, PTW 60017; microDiamond, PTW 60019), EBT3 film, and ionization chambers (Semiflex, PTW 31010; Semiflex 3D, PTW 31021; PinPoint, PTW 31015; PinPoint 3D, PTW 31016) in the small fields formed by 10, 15, 18, and 20 MV photon beams. The output correction factors were calculated by Monte-Carlo method using EGSnrc toolkit for six field sizes (from to ) for isocentric and constant source-to-surface distance (SSD) techniques.

[Results of laparoscopic pelvic exenterations].

Objective: To analyze clinical outcomes after pelvic exenteration for advanced primary or recurrent pelvic cancer.

Material And Methods: We analyzed the outcomes in 35 patients after pelvic exenteration for advanced primary or recurrent pelvic cancer (gynecological cancer, urologic cancers, colon cancer). There were 3 (8.

[The use of rehabilitation programs for patients in the early recovery period after total knee arthroplasty].

Unlabelled: Rehabilitation of patients after total knee arthroplasty is still a challenge for modern medicine. At the same time, there are few publications in the medical literature on rehabilitation programs for patients after total knee arthroplasty. Available scientific studies have proven the effectiveness of low-intensity laser therapy and a pulsed low-frequency electrostatic field (PLFEF) in tissue repair by modulating the inflammatory process and relieving pain.

Chemiluminescence Detection in the Study of Free-Radical Reactions. Part 2. Luminescent Additives That Increase the Chemiluminescence Quantum Yield.

The present review examines the use of chemiluminescence detection to evaluate the course of free radical reactions in biological model systems. The application of the method is analyzed by using luminescent additives that enhance the luminescence thanks to a triplet-singlet transfer of the electron excitation energy from radical reaction products and its emission in the form of light with a high quantum yield; these additives are called chemiluminescence enhancers or activators. Examples of these substances are provided; differences between the so-called chemical and physical enhancers are described; coumarin derivatives, as the most promising chemiluminescence enhancers for studying lipid peroxidation, are considered in detail.

[The electronic technologies of modern marketing in health care and medicine: The foreign publications review].

In conditions of reformation of health care system, just marketing permits health care to penetrate modern economical mechanism of development of economics. In conditions of market relationships, profound investigation of need in medical care instead of waiting for visits of patient for medical care becomes a new standard for for medical organization. The purpose of the study is to examine technologies of modern marketing in forein health care.

The Role of Radiobiology and Nuclear Medicine in Protection from the Effects of Ionizing Radiation (Domestic Experience).

This article presents the domestic experience in nuclear medicine, radiobiology, radiotoxicology, radiation protection, and health maintenance of nuclear industry workers and residents of the region of location of radiation hazardous facilities of the Russian Federation. In addition, the authors address the history and stages in the establishment of nuclear medicine and radiobiology in Russia, as well as modern projects and the prospects of further development of healthcare provision for workers in the nuclear industry.

Russian Consensus on Exo- and Endocrine Pancreatic Insufficiency After Surgical Treatment.

The Russian consensus on exo- and endocrine pancreatic insufficiency after surgical treatment was prepared on the initiative of the Russian Pancreatic Club using the Delphi method. Its goal was to consolidate the opinions of national experts on the most relevant issues of diagnosis and treatment of exo- and endocrine insufficiency after surgical interventions on the pancreas. An interdisciplinary approach is ensured by the participation of leading gastroenterologists and surgeons.

Bringing a Gene-Activated Bone Substitute Into Clinical Practice: From Bench to Bedside.

Bone grafting and reconstruction are still challenging in clinical practice because of the limitations of bone autografts and the drawbacks of currently approved bone substitutes. We thus developed a gene-activated bone substitute based on octacalcium phosphate and naked plasmid DNA carrying the vascular endothelial growth factor gene. This advanced combined therapy medicinal product had no cytotoxic effects , slightly decreased bone marrow mesenchymal stromal cell (MSC) doubling time, and was characterized by a prolonged level of gene construct delivery in a luciferase bioimaging assay.

[The history of development of doctrine of somatotypes: the publications review].

The study required o apply various modes of corresponding publications search through such international databases as RussiaScopus, Web of Science, Medline, The Cochrane Library, EMBASE, Global Health, CyberLeninka, RISC, eLIBRARY.RU. Actually, there are not less than one hundred definitions of constitution of individual.

Bilary anastomotic strictures after right lobe living donor liver transplantation: a single-center experience.

Objective: To determine the incidence of AS after right lobe living donor liver transplantation with various biliary reconstructions and to identify the predictors of this complication.

Material And Methods: A retrospective and prospective analysis included 245 RLLDLTs for the period 2011-2018 at the Burnazjan Federal Medical Biophysical Center. The results of transplantations in 207 patients aged 19-68 years (median 43 years) were assessed.

3D Printed Gene-activated Octacalcium Phosphate Implants for Large Bone Defects Engineering.

The aim of the study was the development of three-dimensional (3D) printed gene-activated implants based on octacalcium phosphate (OCP) and plasmid DNA encoding . The first objective of the present work involved design and fabrication of gene-activated bone substitutes based on the OCP and plasmid DNA with gene using 3D printing approach of ceramic constructs, providing the control of its architectonics compliance to the initial digital models. X-ray diffraction, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and compressive strength analyses were applied to investigate the chemical composition, microstructure, and mechanical properties of the experimental samples.

Behavioral Responses and Immune and Cytogenetic Parameters of Food-Restricted Mice.

The experiments on mice showed that subchronic food restriction to 40 and 8% of unrestricted ration is a strong stressor inducing devastation of lymphoid organs, primarily the thymus and spleen. The mice in the group with severe food restriction (8% of normal ration) demonstrated increased front paw grip force. We also observed an increase in spontaneous motor activity in these animals correlated with food restriction.

Changes in the Activity of Genes Involved in the Regulation of Hematopoiesis during Tumorigenesis in Irradiated Mice.

We used 183 F1 CBA×C57Bl hybrid mice to study the delayed effects of low-power long-term γ-irradiation at a dose of 12.6 Gy (10 mGy/min) 8 and 10 months after the treatment. Eight months after the treatment we found the increased expression of the transcription factor NFκB and its target genes iNOS and G-SCF in the bone marrow (BM).

[Comparative effectiveness of complex physiotherapeutic treatment of patients in the early stages of avascular necrosis of the femoral head].

Introduction: In the late stages of avascular necrosis of the femoral head (ANFH), total hip arthroplasty (THA) is a non-alternative treatment method. In the early stages, methods of conservative treatment show some effectiveness. Among them, most often there is evidence of the effectiveness of physiotherapy options.

[Recurrent hemangioendothelioma of the lower and middle segments of inferior vena cava with spread to previously installed prosthesis].

We report surgical treatment of a 65-year-old patient with recurrent hemangioendothelioma of inferior and middle segment of inferior vena cava with spread to previously established prosthesis. Advanced resection of inferior vena cava and right-sided nephrectomy were not followed by complications and resulted R0 resection. Surgery time was 180 min.

[The prevalence of diseases of non-occupational genesis in persons with diagnosis of occupational disease].

The data on prevalence of diseases of non-occupational genesis in persons with occupational diseases that have stopped their labor activity are presented. The purpose of the study was to analyze prevalence of diseases of non-occupational genesis in persons with diagnose of occupational disease working at enterprises and organizations served by health care institutions of the FMBA of Russia. The study uses data from "The Industrial Register of persons with occupational diseases".

[The impact of the COVID-19 epidemic on the elderly mental health and psychosocial support.].

The spread of the COVID-19 epidemic is accompanied by psychosocial problems that have negative consequences for the mental health (MH) and quality of life (QoL) of the majority of the population. The elderly (65+ individuals) with chronic somatic diseases and reduced adaptation reserves are particularly at risk. In General, the epidemic highlighted the growing problems of psychosocial work with the 65+ cohort in the conditions of progressive aging of the population of many developed and developing countries.

[Primary splenic angiosarcoma].

Primary splenic angiosarcoma is a rare and high-grade vascular tumor having a significant metastatic potential. The authors give the data available in the literature and describe their own case of primary splenic angiosarcoma in a 42-year-old male patient with multiple distant metastases in the lymph nodes and skin. The paper shows some difficulties in the morphologic diagnosis of this tumor.

[The organization of medical nurse support of patients of elderly age in geriatric practice].

In recent years, the concept of nursing process has been actively introduced. It is especially important in geriatric practice, where the issues of nursing support prevail over those in the young and middle age. There are forms of organization of care, where it is the average medical staff is leading in the provision of medical care (hospices, nursing care hospitals, homes for the elderly, etc.

[Impact of external counterpulsation on microcirculation in patients with coronary heart disease complicated by chronic heart failure after surgical and endovascular myocardial revascularization].

Aim: To study the impact of external counterpulsation (ECP) on endothelial function and microcirculation in patients after myocardial revascularization (stenting and coronary artery bypass grafting) for functional class (FC) II-III chronic heart failure (CHF).

Subjects And Methods: Sixty patients aged 50 to 75 years after myocardial revascularization for FC II-III CHF were examined. All the patients received one-hour ECP sessions 5 times per week.