High pyrethroid resistance is associated with high frequencies of 1014F and 1014S kdr mutations in Anopheles arabiensis (Diptera: Culicidae) from Ouagadougou, Burkina Faso.

Malaria remains a major public health threat in Burkina Faso, as in most sub-Saharan Africa countries. Malaria control relies mainly on long-lasting insecticide-treated nets (LLINs) and indoor residual spraying. In Burkina Faso, an escalating of insecticide resistance has been observed over the last decades.

The inhibitory activities of two compounds from Fresen on the acetylcholinesterase from wheat pest Rondani: analysis.

Wheat is the third most widely consumed cereal in the world, after maize and rice. However, it is regularly attacked by the wheat aphid (), causing considerable damage to wheat crops. The acetylcholinesterase enzyme, which plays a key role in the transmission of the synaptic cholinergic signal, has emerged as a promising target for the development of pest control strategies.

Effects of the COVID-19 pandemic on maternal, newborn, and child health service coverage in Burkina Faso.

Background: While countries' coronavirus disease 2019 (COVID-19) emergency contingency and response plans aimed to prevent and control the spread of the virus, they also caused major disruptions to health services. We assessed the effects of COVID-19 on coverage and inequalities in select maternal, newborn, and child health services in Burkina Faso.

Methods: We analysed data from two cross-sectional household surveys conducted in two provinces, one rural and one urban.

Validation of prognostic models predicting mortality or ICU admission in patients with COVID-19 in low- and middle-income countries: a global individual participant data meta-analysis.

Background: We evaluated the performance of prognostic models for predicting mortality or ICU admission in hospitalized patients with COVID-19 in the World Health Organization (WHO) Global Clinical Platform, a repository of individual-level clinical data of patients hospitalized with COVID-19, including in low- and middle-income countries (LMICs).

Methods: We identified eligible multivariable prognostic models for predicting overall mortality and ICU admission during hospital stay in patients with confirmed or suspected COVID-19 from a living review of COVID-19 prediction models. These models were evaluated using data contributed to the WHO Global Clinical Platform for COVID-19 from nine LMICs (Burkina Faso, Cameroon, Democratic Republic of Congo, Guinea, India, Niger, Nigeria, Zambia, and Zimbabwe).

Minimum dietary diversity behaviour among children aged 6 to 24 months and their determinants: insights from 31 Sub-Saharan African (SSA) countries.

Background: Feeding practices during infancy have a significant impact on a child's cognitive development and long-term health outcomes. Dietary diversity guidelines from the WHO and UNICEF recommend a diverse range of foods for children aged below 24 months for their optimal growth and development. However, in sub-Saharan Africa (SSA), little is known about the extent to which dietary diversity behaviour in children aged 6 to 24 months aligns with the recommendations and the factors associated with the differentials in dietary behaviour.

Evaluating artesunate monotherapy and dihydroartemisinin-piperaquine as potential antimalarial options for prevaccination radical cures during future malaria vaccine field efficacy trials.

Background: In malaria vaccine clinical trials, immune responses after vaccination may be compromised due to immunosuppression caused by concurrent Plasmodium falciparum infection. This has a direct effect on the protective efficacy of the vaccine being evaluated. Therefore, parasite clearance prior to vaccination is being considered.

Genomic analyses revealed low genetic variation in the intron-exon boundary of the doublesex gene within the natural populations of An. gambiae s.l. in Burkina Faso.

Background: The recent success of a population control gene drive targeting the doublesex gene in Anopheles gambiae paved the way for developing self-sustaining and self-limiting genetic control strategies targeting the sex determination pathway to reduce and/or distort the reproductive capacity of insect vectors. However, targeting these genes for genetic control requires a better understanding of their genetic variation in natural populations to ensure effective gene drive spread. Using whole genome sequencing (WGS) data from the Ag1000G project (Ag3.

Pesticide residues in three fishing sites in Burkina Faso.

Pesticides control pests and diseases in crops in order to enhance agricultural productivity; however, they are responsible for damaging aquatic resources. This study aimed to assess pesticide residues in aquatic ecosystems in Burkina Faso. Data were collected in two sampling sites: Bama and Banzon.

Pathways From Poverty to Child Mental Health in Burkina Faso: Longitudinal Mediation Analyses in a Cluster-Randomized Clinical Trial.

Purpose: The study applies the Family Stress Model to examine the impact of an integrated intervention on the mental health of children facing chronic adversity in Burkina Faso. Its primary goal is to enhance understanding of individual and relational factors at the family level as mediators and specific mechanisms through which poverty reduction can impact child well-being.

Methods: Cross-lagged autoregressive longitudinal mediation analyses tested the intervention effect on child mental health, examining maternal depression, maternal anxiety, harsh parenting, and child exposure to abuse as potential mediators.

Integrated coagulation-flocculation with nanofiltration and reverse osmosis membrane for treating sugar cane industry effluent.

Sugarcane industries, like other agro-food industries, generate significant volumes of wastewater containing high concentrations of organic and inorganic pollutants. Among the proposed treatment solutions, the anaerobic membrane bioreactor (AnMBR) has proven highly effective in degrading organic pollutants but has limitations in removing color and inorganic pollutants. To address this gap, integrating other technologies with AnMBR is necessary.

Describing Biological Vulnerability in Small, Vulnerable Newborns in Urban Burkina Faso (DenBalo): Gut Microbiota, Immune System, and Breastmilk Assembly.

: Small vulnerable newborns (SVNs), including those born preterm, small for gestational age, or with low birth weight, are at higher risk of neonatal mortality and long-term health complications. Early exposure to maternal vaginal microbiota and breastfeeding plays a critical role in the development of the neonatal microbiota and immune system, especially in low-resource settings like Burkina Faso, where neonatal mortality rates remain high. : The DenBalo study aims to investigate the role of maternal and neonatal factors, such as vaginal and gut microbiota, immune development, and early nutrition, in shaping health outcomes in SVNs and healthy infants.

Intervention accelerator to prevent and respond to abuse of older people: insights from key promising interventions.

Globally, abuse of older people (AOP) affects one in six individuals aged 60 years and older every year. Despite the widespread prevalence of AOP, evidence-based interventions for preventing and responding to this issue are insufficient. To address this gap, WHO proposed an initiative to accelerate the development of effective interventions for AOP across all country income levels.

Genetic analysis of grain yield and related traits of extra-early orange maize inbred lines and their hybrids under drought and rain-fed conditions.

Background: Orange maize genotypes are sources of provitamin A (PVA) carotenoids, which are precursors of vitamin A. PVA deficiency and drought constitute major challenges causing increasing food and nutritional insecurity in sub-Saharan Africa (SSA). Breeding of drought-tolerant provitamin A hybrid maize can mitigate these challenges.

Gender, climate and landowning: Sources of variability in the weather pattern change and ideal fertility relationship in Sahelian West Africa.

This paper advances our understanding of the relationship between climate change and ideal fertility in Sahelian West Africa by exploring sources of variation in that relationship. Using an integrated dataset of Demographic and Health Surveys with monthly rainfall and temperature data, the analyses model dimensions of prospective ideal fertility for young, childless men and women in Senegal, Mali, Burkina Faso and Nigeria. Temperature, particularly in the arid climate zone, is shown to have a positive effect on ideal fertility.

Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled, phase 2b trial in children.

Background: Two pre-erythrocytic vaccines (R21/Matrix-M and RTS,S/AS01) are now approved for Plasmodium falciparum malaria. However, neither induces blood-stage immunity against parasites that break through from the liver. RH5.

Assessing the effectiveness of the Pregnancy And Newborn Diagnostic Assessment system on the quality of antenatal care in Burkina Faso: A cluster-randomised controlled trial.

Introduction: The Pregnancy and Newborn Diagnostic Assessment (PANDA) system is a mobile application designed to facilitate diagnosis and decision-making by healthcare staff in antenatal care (ANC). This study aimed to evaluate its effectiveness in improving the quality of ANC.

Methods: This randomised controlled trial implemented the PANDA system in two groups of health facilities (intervention and comparison groups) using a matched-pair method in the Koupéla health district, Burkina Faso.

Effect of egg consumption on early childhood development: Evidence from study.

Objective: Recent studies have shown that inclusion of eggs in young children's diet can help meet nutritional requirements associated with cognitive development. This study aims to investigate the effect of egg consumption on Early Childhood Development (ECD) using Ages and Stages Questionnaire-3(ASQ-3) in Burkina Faso.

Design: The study presented here uses data collected during a follow-up of the -a 3 arm clustered randomized controlled trial (RCT), conducted roughly four months after the end of the RCT.

Impact of long-term mass-rearing on the genetic structure of tsetse fly Glossina palpalis gambiensis colonies.

Tsetse flies are the sole cyclic vectors of African trypanosomes, which cause human and animal African trypanosomiases in Africa. Tsetse fly control remains a promising option for disease management. The sterile insect technique (SIT) stands as an environmentally friendly tool to control tsetse populations.

Stunting and academic trajectory in urban settings of Burkina Faso.

Background: Impaired growth in childhood can lead to poor cognitive development and low school performance. However, literature on the effects of stunting on school trajectory is very limited. The primary objective of this research was to estimate the age at which children start school according to levels of height-for-age z-score (stunting).

Prevalence of Liver Steatosis Among Workers in Ouagadougou and Associated Factors: A Cross-Sectional Study.

Aims: Liver steatosis prevalence is growing, linked to the current worldwide epidemics of obesity and Type 2 diabetes. In sub-Saharan Africa, data on apparent healthy workers must still be included. This study aimed to determine the prevalence of hepatic steatosis and its associated factors in the workplace.

Bacteriology testing and antimicrobial resistance detection capacity of national tiered laboratory networks in sub-Saharan Africa: an analysis from 14 countries.

Background: Accurate detection of antimicrobial resistance (AMR) depends on adequate laboratory capacity. We aimed to document key weaknesses hindering AMR detection at various tiers of laboratory networks in 14 countries in sub-Saharan Africa, and analyse their significance in AMR surveillance and policies.

Methods: In this analysis, we obtained retrospective data on AMR and antimicrobial consumption from 14 countries participating in the Mapping Antimicrobial Resistance and Antimicrobial Use Partnership between May 1, 2019, and June 30, 2020.

[Mapping access to hypertension management services by general practitioners in Burkina Faso in 2020].

Introduction: arterial hypertension (AH) is a public health problem in Burkina Faso. Its management is not the sole responsibility of the specialist but requires the participation of all healthcare actors within a care network, with the involvement of those at the forefront. This study aimed to analyse and map the capacity for managing hypertension in Burkina Faso.