Noninvasive assessment of the elastance and reserve capacity of the craniovertebral contents via flow velocity measurements in the straight sinus by TCD during body tilting test.

Invasive recording of intracranial pressure (ICP) changes during cerebrospinal fluid (CSF) infusion-drainage tests have been used to estimate elastance and reserve capacity of craniovertebral contents. The increase in ICP and its pulse-related oscillations lead to "cuff constriction" of cerebral veins. The purpose of this study is noninvasive assessment of elastance and reserve capacity of craniovertebral contents (RCCC) by measurement of flow velocity (FV) in the straight sinus by transcranial Doppler (TCD) during body tilt tests, which cause changes in ICP.

[Study of free radical oxidation of lipids in cerebrospinal fluid of hydrocephalic children].

The levels of free radical production, malondialdehyde concentration and antioxidant activity were estimated in ventricular liquor of the infants with primary hydrocephalus. It was shown that even in the case of uncomplicated hydrocephalus significant disorders in brain metabolism took place. In the patients with inflammatory or hemorrhagic complications the levels of malondialdehyde and free radicals were markedly increased as compared to the infants with "pure" hydrocephalus.

The Burdenko Neurosurgery Institute: past, present, future.

The Moscow Institute of Neurosurgery was established in 1932. The institute's founders were Nikolai Nilovich Burdenko, the surgeon (his name was later conferred on the institute), and Vasily Vasilyevich Kramer, the neurologist. This article presents the institute's history and its activities in different periods, including scientific and practical achievements in neuro-oncology, cerebrovascular surgery, and neurotraumatology.

CSF dynamics in patients with meningiomas.

The purpose of this work was to study CSF dynamics and brain elasticity in patients with peritumoral BE. The investigations was carried out in 14 patients with supratentorial meningiomas. The volume of tumor and the volume of BE was determined planimetrically on CT.

3-D computer model of subcortical structures of human brain.

Three-dimensional computer model of thalamus and adjacent formations of human brain has been elaborated on the basis of sagittal slices from the Schaltenbrand-Bailey stereotactic atlas. The model includes 120 morphologically distinguishable structures and consists of more than 16 million points (volume elements) each of them being associated with the particular structure in the brain. The model is stored in the long-term computer memory.