Current Utilization of Bupropion Treatment in Children, Young Adults, and Adults in the United States.

While available for decades, the use of bupropion has increased in recent years. To provide an updated review on the use of bupropion, this article aimed to describe bupropion prescription details, potential indication, and treatment duration in children, young adults, and adults starting bupropion treatment. Individuals aged 6-64 newly initiating bupropion hydrochloride treatment were identified from commercial claims data (MarketScan, 1/1/2016-12/31/2022).

Trends and prevalence of eating disorders in children and adolescents.

Background: Eating disorders (EDs) have increasingly become a public health problem globally, especially among children and adolescents.

Aim: To estimate the burden of EDs in children and adolescents (ages 5-19 years) at the global, regional, and national levels.

Methods: Retrieved from Global Burden of Disease Study 2019 for EDs, including anorexia nervosa and bulimia nervosa, we extracted the disability-adjusted life years (DALYs) and prevalence rates with 95% uncertainty intervals between 1990-2019.

Machine learning models for diagnosis and risk prediction in eating disorders, depression, and alcohol use disorder.

Background: Early diagnosis and treatment of mental illnesses is hampered by the lack of reliable markers. This study used machine learning models to uncover diagnostic and risk prediction markers for eating disorders (EDs), major depressive disorder (MDD), and alcohol use disorder (AUD).

Methods: Case-control samples (aged 18-25 years), including participants with Anorexia Nervosa (AN), Bulimia Nervosa (BN), MDD, AUD, and matched controls, were used for diagnostic classification.

Ngā Māuiui Kai: creating Indigenous Māori terms for eating disorders in Aotearoa New Zealand.

Background: Māori (the Indigenous people of Aotearoa New Zealand) report higher rates of eating disorders than non-Māori, but access treatment at lower rates. Diagnostic terms lacking in cultural relevance likely contribute to Māori exclusion in eating disorder spaces. Developing terms in te reo Māori (the Māori language) presents an opportunity to challenge eating disorder stereotypes and increase cultural safety in the eating disorder workforce.

Can people with longstanding bulimia nervosa suffer from severe and enduring eating disorder? A qualitative study.

Objectives: To interview a series of individuals with bulimia nervosa of longstanding to establish their symptoms and examine the suggestion, using qualitative analysis, that the term "Severe and Enduring Bulimia Nervosa (SEED-BN)" might be appropriate and helpful.

Methods: 12 participants with Bulimia Nervosa, one male, were interviewed with the help of an interview guide. Interviews were recorded and transcribed.

[The Eating Attitude Test (EAT-26): assessment of psychometric characteristics in a sample of patients with depression].

Objective: To analyze the psychometric properties of the Eating Attitudes Test (EAT-26) in a Russian sample of patients with a depressive episode (DE) and recurrent depressive disorder (RDD).

Material And Methods: This multicenter cross-sectional study included 338 people (216, 63.9% women), aged 18-59 years, with diagnoses of DE/ RDD.

Prevalence of Emotional and Binge Eating Among Patients With Obesity Attending a Specialist Weight Management Service for Bariatric Surgery in the United Kingdom.

Background: Emotional eating (EE) is a tendency to consume food in response to positive or negative emotions, leading to obesity and an increased Body Mass Index (BMI). Evidence supports the positive association between EE and binge eating disorder (BED), but little is known about its prevalence among patients referred for bariatric surgery and the psychological characteristics of this patient population. We aim to examine (i) the prevalence of binge eating and EE, (ii) its association with the prevalence of anxiety, depression, diabetes and hypertension and (iii) the correlation between anxiety and depression with emotional and binge eating behaviours among patients attending a regional bariatric service in the UK.

Eating Attitudes and Characteristics of Physical Activity Practitioners and Athletes in Riyadh, Saudi Arabia.

Disordered eating among athletes and physical activity practitioners is a growing concern that can negatively impact health and performance. Understanding the prevalence and predictors of disordered eating in these populations is essential for developing effective interventions. To investigate disordered eating tendencies among athletes and physical activity practitioners in Riyadh, Saudi Arabia.

Editorial: Biological Therapies and Eating Disorders.

Objective: Blood-based biomarkers and neuroimaging techniques have improved our understanding of the underlying biology of eating disorders (EDs) and have increased our diagnostic portfolio.

Method: This editorial accompanies an article collection on novel biological approaches to treat EDs.

Results: The collection covers intermittent theta burst stimulation, therapeutic drug monitoring, pharmacological treatments (olanzapine, metreleptin, psychedelics, and anti-inflammatory medications), microbiome-based treatments such as pro- and prebiotics, as well as individually tailored treatment approaches for EDs.

Understanding Early Treatment Response in Brief CBT for Nonunderweight Eating Disorders: A Mixed Methods Study.

Objective: Early change in eating disorder psychopathology is the most robust predictor of treatment outcomes in eating disorders. However, little is known about what predicts early change. Using mixed-methodology, this study explored predictors of early change in the first four sessions of 10-session cognitive behavioral therapy (CBT-T) for nonunderweight eating disorders.

Association of Dietary Intake with Interoception and Gastric Myoelectric Activity in Women with Binge Eating Disorder and Bulimia Nervosa.

Background: Women with binge eating disorder (BED) and bulimia nervosa (BN) usually consume high-calorie meals with variable macro- and micronutrient compositions and have a disturbed perception of gastric fullness. The association of dietary intake with gastric interoception and gastric myoelectric activity (GMA) is poorly studied. This study examined the link between GMA/interoception and dietary intake in women with eating disorders (ED) compared to age/body mass index (BMI)-matched controls.

Patient perceptions of lisdexamfetamine as a treatment for binge eating disorder: An exploratory qualitative and quantitative analysis.

Lisdexamfetamine (LDX) is the only medication to have gained FDA approval for the treatment of binge eating disorder (BED). LDX treatment is generally effective at reducing binge eating symptoms but is associated with several unwanted side effects. How BED patients perceive the therapeutic efficacy vs.

Translation and cross-cultural adaptation of a portuguese version of the eating disorder assessment for DSM-5 (EDA-5) for Brazil and Portugal.

The EDA-5 was translated from English to Portuguese, followed by a cross-cultural adaptation for use in Brazil and Portugal. Two independent translators worked on the Brazilian and European Portuguese versions, which were then reviewed to create a harmonized version. This version was back-translated into English and approved by the original author.

Eating Disorders, Co-Morbid Disorders and Early Risk Factors Amongst Post-9/11 Veteran Men and Women.

Objective: To assess, by interview, the rates of eating disorders in a nationally representative sample of recent veterans, describe their DSM-5 eating disorder diagnoses and the occurrence of comorbid psychiatric disorders. To conduct an exploratory case-control analysis of previously documented and additional specific military risk factors before eating disorder onset to inform studies of prospective risk.

Method: Using a two-stage design, probable cases and controls were identified by screening questionnaires from a sample of 1494 veterans who completed a survey study and interviewed to establish case status and confirm probable co-morbid psychiatric diagnoses.

A scoping review and hypothetical framework about the interplay between oxytocin and eating disorders.

Introduction: Despite emerging evidence on oxytocin's role in eating disorders,there is a need for a comprehensive review to integrate findings across neurobiological, genetic, hormonal, and therapeutic dimensions. This scoping review synthesizes existing literature on OXT's role in EDs and proposes a new theoretical perspective based on diverse research findings.

Methods: In accordance with PRISMA guidelines, we systematically synthesized all peer-reviewed articles indexed on PubMed which focused on both OXT and EDs as of December 2023 (k = 32 studies, n = 1942 participants).

Leptin Levels in Acute and Recovered Eating Disorders: An Arm-Based Network Meta-Analysis.

Objective: This study aimed to provide a BMI-adjusted meta-analytical calculation of blood leptin levels across different eating disorders (EDs) including anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), recovered EDs, and healthy controls (HCs). The goal was to understand BMI-independent leptin alterations and their potential as biomarkers.

Method: PubMed and ClinicalTrials.

An FMRI meta-analysis of interoception in eating disorders.

Eating Disorders (EDs) are associated with disturbed interoception - the sense of the internal condition of the body. Disturbances in interoception across senses have not yet been comprehensively examined in EDs. To do so, we employed an innovative Bayesian author-topic model approach to fMRI meta-analyses that pools together neural deficits across interoceptive senses and task types in participants with and recovered from EDs.