Case presentation of acute ischemia induced ST-depression masking Brugada syndrome ECG pattern in a relatively young patient.

ECG in Brugada syndrome (BrS) is characterized by a ST-segment elevation in the right precordial leads. Overlap between ST-segment changes in BrS and ischemia may lead to diagnostic challenges. We report a case of a male patient presented with recurrent chest pain episodes and ST elevation in the right precordial leads consistent with Brugada ECG pattern type 1 and was clinically diagnosed with BrS at the age of 30 years.

Intraoperative ST Segment Depression During General Anesthesia in a Child: Early Detection of Hypertrophic Cardiomyopathy.

Continuous electrocardiographic (ECG) monitoring remains crucial during surgery in infants and children. Although generally uncommon in pediatric-aged patients, ECG changes may occasionally be indicative of a variety of myocardial pathologies including anomalous origin of coronary arteries, ventricular hypertrophy, myocarditis, hypothermia, drug effects, electrolyte abnormalities, acid-base disturbances or conduction system disorders such as Wolff-Parkinson-White and Brugada syndrome. Distinguishing between pathologic and non-pathologic conditions impacting the ECG must be considered so that appropriate interventions are provided to prevent perioperative morbidity and mortality.

Retraction: Identification of novel SCN5A single nucleotide variants in Brugada syndrome: a territory-wide study from Hong Kong.

[This retracts the article DOI: 10.3389/fphys.2020.

Brugada phenocopy in fulminant eosinophilic myocarditis: a case series.

Background: Brugada phenocopy (BrP) is a condition that induces reversible Brugada-like electrocardiographic (ECG) changes in patients without true Brugada syndrome. We present two cases of fulminant eosinophilic myocarditis that showed Type 1 Brugada ECG changes in the early phase of the clinical course.

Case Summary: Case 1 was a 76-year-old man who developed fulminant eosinophilic myocarditis with ventricular tachycardia while hospitalized for heart failure.

Retraction: Ventricular tachyarrhythmia risk in paediatric/young vs. adult Brugada Syndrome patients: a territory-wide study.

[This retracts the article DOI: 10.3389/fcvm.2021.

[Clinical and electrocardiographic characteristics of carriers with SCN5A mutations and non-SCN5A mutations in fever-induced Brugada syndrome].

To investigate the differences in clinical and electrocardiographic characteristics between carriers of SCN5A mutations and non-SCN5A mutations in fever-induced Brugada syndrome. This study is a retrospective cohort study. A total of 263 patients with fever-induced Brugada syndrome who were admitted to Renmin Hospital of Wuhan University from January 2000 to December 2023 were selected.

Non-invasive Assessment of HydroQUInidine EffecT in Brugada Syndrome (QUIET BrS).

Background: Hydroquinidine reduces arrhythmic events in patients with Brugada syndrome (BrS). The mechanism by which it exerts antiarrhythmic benefit and its electrophysiological effects on BrS substrate remain incompletely understood.

Objective: This study aimed to determine the effect of Hydroquinidine on ventricular depolarisation and repolarisation in patients with BrS in vivo.

A Matlab Toolbox for cardiac electrophysiology simulations on patient-specific geometries.

In this paper, we present CardioMat, a Matlab toolbox for cardiac electrophysiology simulation based on patient-specific anatomies. The strength of CardioMat is the easy and fast construction of electrophysiology cardiac digital twins from segmented anatomical images in a general-purpose software such as Matlab. CardioMat implements a quasi-automatic pipeline that guides the user toward the construction of anatomically detailed cardiac electrophysiology models.

Validation and clinical implications of higher intercostal space electrocardiography in the patient with Brugada syndrome in Taiwan (SADS-TW BrS registry).

Background: Diagnosis of Brugada syndrome (BrS) is based on type 1 morphology (coved type) in electrocardiograms from standard (4) or higher (2 or 3) intercostal spaces (ICSs). However, the clinical implications of being diagnosed only at higher ICSs remains poorly understood. We aimed to investigate the diagnostic accuracy of higher ICS leads in the Taiwanese Brugada syndrome population and clarify if there is any difference in clinical presentation.

SURFBAT: a surrogate family-based association test building on large imputation reference panels.

Genotype-phenotype association tests are typically adjusted for population stratification using principal components that are estimated genome-wide. This lacks resolution when analysing populations with fine structure and/or individuals with fine levels of admixture. This can affect power and precision, and is a particularly relevant consideration when control individuals are recruited using geographic selection criteria.

Differences in clinical significance of atrial tachyarrhythmias in idiopathic ventricular fibrillation vs Brugada syndrome: A multicenter study.

Background: Atrial tachyarrhythmias (ATAs) are the primary cause of inappropriate implantable cardioverter-defibrillator (ICD) therapy in patients with idiopathic ventricular fibrillation (IVF) and are associated with decreased quality of life and increased mortality. Nonetheless, the incidence of ATAs in IVF cases has not been clarified.

Objective: The study sought to determine the incidence and clinical significance of ATAs in patients with IVF compared with those with Brugada syndrome (BrS).

Prevalence and Incidence of Type 1 Brugada Pattern: A 30-Year Experience at Mayo Clinic.

Objective: To identify the incidence and prevalence of type 1 Brugada pattern at Mayo Clinic during 30 years.

Methods: We retrospectively reviewed the electronic medical records from 1992 to 2021 at Mayo Clinic Enterprise. Patients with type 1 Brugada pattern electrocardiogram (ECG) were identified by a systematic keyword search.