1,804 results match your criteria: "Bromhidrosis"

This review evaluates the risks and benefits of botulinum toxin (BTX) therapy for treating bromhidrosis. A search was conducted across six databases, including clinical trials comparing BTX therapy with BTX-free controls. The analyzed outcomes included pooled adverse events (AEs), treatment success, ≥ 50% overall improvement, and recurrence rates.

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Axillary osmidrosis (AO) affects a large number of young people in Asia, resulting from a combination of body and bacterial metabolism. This study aimed to explore the pathogenesis of AO through proteomics. Apocrine gland tissues from 3 mild and 3 severe AO patients were analyzed using 4D label-free proteomics, followed by bioinformatics analysis.

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Experience of negative pressure fractional microneedle radiofrequency therapy for axillary osmidrosis: a case study.

Arch Dermatol Res

December 2024

Department of Plastic Surgery, ZhongshanCity People's Hospital, 2 Sunwen East Road, Zhongshan, 528400, Guangdong, China.

Background: Negative pressure fractional microneedle radiofrequency (NPFMR) therapy has emerged as a potential minimally invasive treatment for axillary osmidrosis (AO), a condition characterized by persistent strong body odor from the armpit area.

Methods: This case study aims to assess the efficacy and safety of NPFMR for AO treatment. From January to September 2024, 30 patients with AO were recruited, with a gender distribution of 19 females and 11 males, aged 17-34 years (mean 23).

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Purpose: the purpose of this study was to evaluate the content, readability, understandability, and suitability of online resources for patient specific ostomy care.

Design: Retrospective cohort study.

Subject And Setting: Online websites for ostomy care designed for patients.

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Article Synopsis
  • Dogs are crucial in forensic science due to their exceptional ability to detect scents, particularly for drugs and explosives.
  • The study involved two groups of dogs – sport detection dogs and law enforcement explosive detection dogs – to assess how their sniffing dynamics change with training on specific odorants.
  • Results showed that dogs increased their sniffing frequency as they gained experience with target odors, with law enforcement dogs taking in larger volumes of air compared to sport detection dogs.
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  • This research examines how body odors transfer to different textile fibers using a method that mimics liquid sweat, focusing on a variety of odorous volatile organic compounds.
  • A study was conducted using proton transfer reaction mass spectrometry to measure the release of these compounds at different time intervals across six types of fabrics.
  • Results show that cellulosic fibers (like cotton) retain odors differently compared to synthetic fibers (like nylon and polyester), with variations in the intensity of ketones and aldehydes released over time.
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It is well known that the development of neurodegeneration, and especially Alzheimer's disease (AD), is often accompanied by impaired olfaction which precedes memory loss. A neuropeptidase neprilysin (NEP)-a principal amyloid-degrading enzyme in the brain-was also shown to be involved in olfactory signalling. Previously we have demonstrated that 5xFAD mice develop olfactory deficit by the age of 6 months which correlated with reduced NEP expression in the brain areas involved in olfactory signalling.

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Introduction: is a member of the Gram-positive anaerobic cocci group and constitutes the flora of the skin and other parts of the body. It sometimes colonizes diabetic foot and rarely infects skin or soft tissue of non-immunocompromised patients.

Case Presentation: Here, we report the case of a severe subcutaneous abscess on the back caused by .

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Prospects on non-canonical olfaction in the mosquito and other organisms: why co-express?

Curr Opin Insect Sci

February 2025

Department of Biology, Boston University, Boston, MA 02143, USA; Center for Systems Neuroscience, Boston University, Boston, MA 02143, USA. Electronic address:

The Aedes aegypti mosquito utilizes olfaction during the search for humans to bite. The attraction to human body odor is an innate behavior for this disease-vector mosquito. Many well-studied model species have olfactory systems that conform to a particular organization that is sometimes referred to as the 'one-receptor-to-one-neuron' organization because each sensory neuron expresses only a single type of olfactory receptor that imparts the neuron's chemical selectivity.

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The medial prefrontal cortex (mPFC) plays a key role in memory and behavioral flexibility, and a growing body of evidence suggests that the prelimbic (PL) and infralimbic (IL) subregions contribute differently to these processes. Studies of fear conditioning and goal-directed learning suggest that the PL promotes behavioral responses and memory retrieval, while the IL inhibits them. Other studies have shown that the mPFC is engaged under conditions of high interference.

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Sniffing out a solution: How emotional body odors can improve mindfulness therapy for social anxiety.

J Affect Disord

January 2025

Department of General Psychology, University of Padua, Via Venezia 8, 35131 Padua, Italy; Padova Neuroscience Center (PNC), University of Padua, Via Orus 2/B, 35131 Padua, Italy.

Background: Human body odors (BOs) serve as an effective means of social communication, with individuals exposed to emotional BOs experiencing a partial replication of the sender's affective state. This phenomenon may be particularly relevant in conditions where social interactions are impaired, such as social anxiety. Our study aimed to investigate if emotional human BOs could augment the benefits of mindfulness-based interventions.

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The production of human body odor is the result of the action of commensal skin bacteria, including Staphylococcus hominis, acting to biotransform odorless apocrine gland secretions into volatile chemicals like thioalcohols such as 3-methyl-3-sulphanylhexan-1-ol (3M3SH). As the secreted odor precursor Cys-Gly-3M3SH contains a dipeptide, yet the final enzyme in the biotransformation pathway only functions on Cys-3M3SH, we sought to identify the remaining step in this human-adapted biochemical pathway using a novel coupled enzyme assay. Purification of this activity from S.

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Article Synopsis
  • The study explored how different roasting degrees (light, medium, dark) affect the properties and sensory characteristics of ultra-high-pressure (UHP) cold brew coffee compared to traditional cold brew coffee.
  • While many physical characteristics of UHP coffee were similar to conventional cold brew, certain chemical components, like antioxidants and caffeine, significantly increased with darker roasting degrees.
  • Sensory analysis revealed that darker roasts enhanced nutty flavors and bitterness while reducing floral and fruity notes, and fewer differences were found in UHP coffee compared to conventional cold brew regarding the impact of roasting degree.
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  • A study investigated weight changes in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) receiving Dupilumab therapy, focusing on the link between weight gain and improved sense of smell over a year.
  • Results showed significant weight gain and olfactory improvement in patients who had mild smell dysfunction or normal smell before treatment, while those with complete loss of smell did not experience significant weight changes.
  • The findings suggest that improvements in nasal function from the treatment may impact weight, but further research is needed to clarify the relationship between olfactory changes and weight regulation in CRSwNP patients.
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  • A virtual surgery planning (VSP) tool has been developed to help surgeons visualize and modify obstructive tissue in endoscopic sinus surgeries using patient-specific CT data, improving functional outcomes like nasal airflow.
  • The tool provides real-time feedback on airflow resistance and pressure, allowing for iterative adjustments until optimal results are achieved.
  • In a proof-of-concept case with a patient experiencing olfactory losses, the VSP tool showed that a medial partial middle turbinectomy resulted in better airflow compared to traditional methods, highlighting its potential as a valuable preoperative planning resource.
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Identification of acrolein as a novel diagnostic odor biomarker for 1,2,3-trichloropropane-induced hepatotoxicity in Sprague Dawley rats.

Toxicol Res

October 2024

Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animals Resources Center, College of Natural Resources and Life Science, Pusan National University, Miryang, 50463 Republic of Korea.

Article Synopsis
  • Body odor can indicate various diseases, but this study specifically aimed to identify odor biomarkers linked to chemical-induced liver damage in rats.
  • Researchers treated Sprague Dawley rats with different doses of 1,2,3-trichloropropane (TCP) and tracked changes in urine odors using gas chromatography-mass spectrometry (GC-MS).
  • They discovered significant increases in several odors, particularly acrolein, which correlated with liver toxicity indicators and expressions of related metabolic enzymes, suggesting acrolein could serve as a new diagnostic marker for liver damage from TCP exposure.
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The Effects of Diet, Dietary Supplements, Drugs and Exercise on Physical, Diagnostic Values of Urine Characteristics.

Nutrients

September 2024

Department of Toxicology and Food Science, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Street, 02-091 Warsaw, Poland.

Article Synopsis
  • This review discusses how various factors like diet, hydration, and medications can change urine characteristics such as color, odor, and pH, and emphasizes the importance of proper sample collection.
  • Urinalysis is a simple test used to detect health issues related to the kidneys and hormones, and abnormal urine properties may indicate underlying diseases.
  • While urinalysis isn't advised as a routine test for everyone, it can provide valuable health insights that help doctors and pharmacists make better diagnoses and treatment plans.
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  • Animals use various strategies to navigate complex odor environments and find scent sources.
  • Researchers are now able to record real-time olfactory information in freely moving mice, making it easier to study their navigation behaviors.
  • The study reveals that during odor-guided tasks, mice make specific head movements linked to odor plume encounters, suggesting that these motions are crucial for locating odor sources.
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  • - The study aimed to examine how Ramadan fasting affects the sense of smell by analyzing participants' olfactory function over the fasting period.
  • - Sixty-two participants underwent olfactory tests at the start and the 30th day of fasting, with results showing significant improvements in odor detection and identification, particularly for food-related smells.
  • - Overall, the findings suggest that Ramadan fasting may enhance olfactory performance, as demonstrated by higher scores in various olfactory tests conducted during the study.
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  • The Social Odor Scale (SOS) is a 12-item questionnaire designed to assess how people perceive social odors from others, focusing on romantic partners, familiar people, and strangers.
  • The study aimed to validate the SOS in several languages (French, English, Dutch, Swedish, Chinese) and found that its structure remained consistent across these translations.
  • Results revealed differences in social odor awareness by language group, with Swedish participants showing the least awareness and Chinese participants the most, while geographical factors also influenced scores, linking higher latitudes to lower social odor awareness.
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  • Olfactory decline may signal neurodegenerative diseases, and recent studies show physical exercise improves olfactory function and involves the prefrontal cortex (PFC), which also handles cognition and emotions.
  • Our research compared healthy older adults who exercised regularly to those who didn't, finding exercisers had a lower odor detection threshold and stronger connectivity between the olfactory cortex and various PFC subregions.
  • Specifically, we observed enhanced connectivity in exercisers, particularly between the ventrolateral prefrontal cortex (VLPFC) and orbitofrontal cortex (OFC), suggesting that regular exercise benefits both olfactory performance and brain connectivity related to smell processing.
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  • Most patients report changes in "taste" after metabolic surgery, but controlled studies show no real changes in taste intensity when tested under specific conditions.
  • The study compared women who had metabolic surgery with non-surgery control groups to see if reported taste changes were linked to other factors like smell rather than actual taste.
  • Results indicated that while surgery patients perceived certain smells (like coffee) more intensely than the healthy BMI group, there were no significant differences in taste or flavor ratings between groups, suggesting taste changes might not drive dietary changes post-surgery.
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