13 results match your criteria: "Brody School of Medicine and Vidant Medical Center[Affiliation]"

Article Synopsis
  • A phase 3 clinical trial assessed the safety and effectiveness of rivipansel, an E-selectin antagonist, in 345 patients (adults and children) with vaso-occlusive crises (VOC) requiring hospitalization.
  • The study found that rivipansel did not significantly improve the primary endpoint of time to readiness for discharge compared to placebo, although it did notably reduce soluble E-selectin levels in the treatment group.
  • A post hoc analysis suggested that administering rivipansel early after VOC pain onset could significantly decrease the time to discharge and reduce opioid use, indicating that the timing of treatment may be key for better outcomes.
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The Definition of Severe Aortic Stenosis: A Remarkably Elusive Target.

JACC Cardiovasc Imaging

July 2022

Brody School of Medicine and Vidant Medical Center, East Carolina University, Greenville, North Carolina, USA. Electronic address:

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Steadfast leadership from key advocacy groups and individuals working to eliminate disparities in the care and treatment of incarcerated pregnant people in North Carolina jails and prisons led to the passage of HB608, Dignity for Women Who are Incarcerated, in 2021.

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Cancer transmission from a donor organ to a transplant recipient is a rare but not infrequently fatal event. We report a case of lung cancer transmission from a deceased donor to 2 kidney recipients. Approximately 1 year after uneventful kidney transplantation, both recipients developed acute kidney failure.

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A New Chapter in the Biology of Mitral Regurgitation as Told by the Left Atrium.

JACC Basic Transl Sci

February 2020

East Carolina Heart Institute, Brody School of Medicine and Vidant Medical Center, East Carolina University, Greenville, North Carolina.

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Bioprosthetic Valve Leaflet Thrombosis: How the Past May Inform Us About the Future.

J Am Coll Cardiol

March 2020

East Carolina Heart Institute, Brody School of Medicine and Vidant Medical Center, East Carolina University, Greenville, North Carolina. Electronic address:

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This analysis of 2017 data from the Open Payments Program (OPP) database examines nonresearch industry payments to directors of caronary catheterization and electrophysiology laboratories to characterize payments across 13 OPP-defined categories.

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Objectives: This study sought to determine the prevalence of reduced contractility and uncompensated wall stress in patients with aortic stenosis (AS) with preserved or reduced left ventricular ejection fraction (LVEF) and their impact on survival.

Background: LVEF in AS is determined not only by contractility but also by loading conditions.

Methods: Patients with first diagnosis (time 0) of severe AS (aortic valve area [AVA]≤1 cm) with prior echo study (-3±1 years) were identified.

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Background: Some patients need their 4 generation HIV testing results confirmed with molecular testing after primary confirmatory testing which may not be immediately available. Further risk stratification of these patients pending the results of molecular testing may be of value not only for patient counseling but also for treatment of women in labor.

Objectives: To determine the risk of a positive test result on molecular testing for these patients.

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This study was conducted to ascertain the opinions of endocrinologists about diabetes care as it relates to the health care provider workforce. A survey was administered to endocrinologists in the Planning Research in Inpatient Diabetes and Planning Research in Outpatient Diabetes (PRIDE/PROUD) group and given to attendees of the American Diabetes Association (ADA) Scientific Sessions special interest group whose focus was primary care. The majority of respondents agreed that there is a need for more providers to be trained to take care of patients with diabetes and that more trained providers are needed, and almost half agreed that primary care providers (PCPs) with advanced training in diabetes should be part of the workforce for managing the diabetes pandemic.

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Where Do Low-Gradient, Low-EF AS Patients Come From?: Maybe They're Born That Way.

J Am Coll Cardiol

March 2018

Brody School of Medicine and Vidant Medical Center, East Carolina University, Greenville, North Carolina. Electronic address:

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Only 50 years ago obstetric care providers and women had many concerns regarding whether exercise during pregnancy created a harmful competition for substrate resources between the fetus and the mother. Animal and human research in the past 50 years, which includes acute and chronic aerobic exercise during pregnancy, has a reassuring margin of safety throughout gestation in women. Maternal physiology adapts to pregnancy changes involving the cardiorespiratory and glucometabolic alterations.

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