3 results match your criteria: "Brockton Veterans Affairs Medical Center and Harvard Medical School.[Affiliation]"
An MRI study of temporal lobe abnormalities and negative symptoms in chronic schizophrenia.
Schizophr Res
December 2002
Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Brockton Veterans Affairs Medical Center and Harvard Medical School, Boston, MA 02301, USA.
Previous magnetic resonance imaging (MRI) studies have reported various subtle brain abnormalities in schizophrenic patients, including temporal lobe abnormalities, which are of particular interest given the role of this brain region in auditory and language processing, and the characteristic deficits in these processes in schizophrenia. Subjects in this study were 16 male patients diagnosed with chronic schizophrenia and 15 healthy male comparison subjects. These patients were characterized by negative symptoms.
View Article and Find Full Text PDFLeft planum temporale volume reduction in schizophrenia.
Arch Gen Psychiatry
February 1999
Department of Psychiatry, Brockton Veterans Affairs Medical Center and Harvard Medical School, Boston, Mass 02401, USA.
Background: The planum temporale, located on the posterior and superior surface of the temporal lobe, is a brain region thought to be a biological substrate of language and possibly implicated in the pathophysiology of schizophrenia. To investigate further the role of planum temporale abnormalities in schizophrenia, we measured gray matter volume underlying the planum temporale from high spatial resolution magnetic resonance imaging techniques.
Methods: Sixteen male patients with chronic schizophrenia and 16 control subjects were matched for age, sex, handedness, and parental socioeconomic status.