5 results match your criteria: "British Columbia Women and Children's Hospital and the University of British Columbia[Affiliation]"
Quality improvement programmes in paediatric sepsis from a global perspective.
Lancet Child Adolesc Health
September 2024
Global Child Health Department of Pediatrics and Emergency Medicine, British Columbia Women and Children's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Article Synopsis
- * Children are particularly vulnerable to sepsis due to their unique physiological responses, necessitating focused interventions for early recognition and treatment.
- * Effective quality improvement efforts for paediatric sepsis are limited worldwide; comprehensive programs must address prevention, awareness, and long-term support to enhance outcomes and foster global collaboration.
Susceptibility to childhood sepsis, contemporary management, and future directions.
Lancet Child Adolesc Health
September 2024
Department of Intensive Care and Neonatology, and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia. Electronic address:
Article Synopsis
- * Pediatric patients have unique vulnerabilities to sepsis due to factors like their developing immune systems, genetic predispositions, and differing environmental influences, which make their management different from adults.
- * Effective treatment for pediatric sepsis focuses on diagnosis, early resuscitation, and advanced care, but there are significant gaps in research and quality improvement efforts, with digital health offering potential solutions to enhance care and outcomes.
The burden and contemporary epidemiology of sepsis in children.
Lancet Child Adolesc Health
September 2024
Department of Intensive Care and Neonatology and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia. Electronic address:
Sepsis is a dysregulated host response to infection that leads to life-threatening organ dysfunction. Half of the 50 million people affected by sepsis globally every year are neonates and children younger than 19 years. This burden on the paediatric population translates into a disproportionate impact on global child health in terms of years of life lost, morbidity, and lost opportunities for children to reach their developmental potential.
View Article and Find Full Text PDFOperationalizing Appropriate Sepsis Definitions in Children Worldwide: Considerations for the Pediatric Sepsis Definition Taskforce.
Pediatr Crit Care Med
June 2023
Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.
Sepsis is a leading cause of global mortality in children, yet definitions for pediatric sepsis are outdated and lack global applicability and validity. In adults, the Sepsis-3 Definition Taskforce queried databases from high-income countries to develop and validate the criteria. The merit of this definition has been widely acknowledged; however, important considerations about less-resourced and more diverse settings pose challenges to its use globally.
View Article and Find Full Text PDFFactors Associated with Umbilical Venous Catheter Malposition in Newborns: A Tertiary Center Experience.
Am J Perinatol
December 2022
Division of Neonatology, Department of Pediatrics, BC Women's and Children's Hospital and the University of British Columbia, Canada.
Objective: Umbilical venous catheters (UVC) are widely used in neonatal intensive care (NICU). Noncentral catheter position is known to be associated with multiple adverse complications; however, risk factors for catheter malposition are unclear. This work aimed to identify clinical risk factors and complications associated with UVC malposition in neonates admitted in an NICU.
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