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Article Synopsis
  • The study aimed to investigate whether aldosterone secretion has a circadian rhythm independent of the sleep/wake cycle, given that urine output and various hormones display daily variations.
  • Ten healthy participants followed a strict 57.3-hour protocol that included both sleep and wake periods, with blood samples taken every 4 hours to measure aldosterone levels.
  • Results showed a clear circadian rhythm in aldosterone secretion, being higher at the end of the biological night and lower at the end of the biological day, confirming that both circadian rhythm and sleep/wake cycle influence aldosterone levels.
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