1,094 results match your criteria: "Bridgeport Hospital[Affiliation]"

Repair of Microperforate Hymen.

J Pediatr Adolesc Gynecol

January 2025

Division of Pediatric and Adolescent Gynecology, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine.

Objective: Subocclusive variants of the hymen are a group of hymenal anomalies that result due to a failure of canalization of the urogenital sinus. One of these variations is the microperforate hymen, for which accurate incidence is unknown. Microperforate hymen is a non-obstructing variation that allows for menstrual egress and often patients present due to inability to use a tampon.

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Transcatheter Aortic Valve Replacement in Hypertrophic Cardiomyopathy: A Systematic Review and Meta-Analysis.

Catheter Cardiovasc Interv

January 2025

Division of Cardiovascular Diseases, Bridgeport Hospital, Yale New Haven Health, Bridgeport, Connecticut, USA.

Background: The co-existence of severe aortic stenosis (AS) and hypertrophic cardiomyopathy (HCM) is not uncommon. Surgical intervention is the gold standard management. Patients with high surgical risk might undergo transcatheter aortic valve replacement (TAVR).

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Background: Recognizing factors that predict non-operative management (NOM) failure for patients with small bowel obstruction (SBO) aids in limiting surgical intervention when needed. This study investigated the predictive factors for NOM failure in SBO patients in a resource-limited setting.

Material And Method: A retrospective study included 165 patients who were diagnosed with SBO and were admitted and managed at Althora General Hospital, IBB, Yemen, from April 2022 to March 2024.

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Objective: In recent years, the application of robotic assistance in diagnostic and therapeutic endovascular neurointerventional procedures has gained notable attention. In this systematic review and meta-analysis, we aim to evaluate the feasibility, safety, and current indications of robotic-assisted neurointerventions and to assess the degree of robotic assistance and reasons for unplanned manual conversion from robotic assistance.

Methods: We searched Medline, Scopus, Web of Science, and Cochrane Library databases following PRISMA guidelines and included studies with ≥ 4 patients reporting on robotic-assisted neurointerventions.

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Breast artery calcification (BAC) obtained from standard mammographic images is currently under evaluation to stratify risk of major adverse cardiovascular events in women. Measuring BAC using artificial intelligence (AI) technology, we aimed to determine the relationship between BAC and coronary artery calcification (CAC) severity with Major Adverse Cardiac Events (MACE). This retrospective study included women who underwent chest computed tomography (CT) within one year of mammography.

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Acquired von Willebrand syndrome (aVWS) is a rare hematological disorder depicted by dysfunctional or deficient von Willebrand factor activity and can be associated with underlying hematological malignancies such as non-Hodgkins lymphoma (NHL). This case report examines a patient with aVWS secondary to NHL and highlights the challenges in managing bleeding and optimizing a patient for surgery. The case report will explore the multidisciplinary approach to recognizing aVWS, treatment modalities, and adjunctive measures to reduce bleeding risk as well as long-term management.

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Background: Liver cirrhosis is not included in surgical risk prediction models despite being a significant risk factor associated with high periprocedural morbidity and mortality in patients undergoing cardiac surgery. Limited contemporary data exists assessing the outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with cirrhosis.

Methods: Patients with cirrhosis who underwent TAVR or SAVR were identified from the Nationwide Readmissions Database.

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Mechanical clot disruption during pulmonary thromboembolectomy is safe: A propensity score-matched analysis.

Clin Imaging

December 2024

Division of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, United States of America. Electronic address:

Purpose: Aspiration thromboembolectomy is effective for treatment of high and intermediate-high risk pulmonary emboli (PE) but can be challenging when organized thrombus is present. Maceration using an expandable nitinol disk may be useful in these situations, but its safety has not been determined. The purpose of this study was to retrospectively assess the safety of this device when applied in the pulmonary vasculature, using a propensity-score matched group for comparison.

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Background: Use of online crowdfunding to mitigate health-related cost burden is common in the US, but its usage among candidates for metabolic and bariatric surgery (MBS) is unknown. We aimed to identify GoFundMe campaigns fundraising for MBS and characterize sources of financial strain. We also aimed to determine factors associated with successful crowdfunding.

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A rare case of endoscopic visualization of a metallic coil in a duodenal ulcer after transcatheter arterial embolization.

Oxf Med Case Reports

November 2024

Department of Medicine, Section of Digestive Diseases, Yale School of Medicine, 333 Cedar St, New Haven, CT 06510, United States.

Transcatheter arterial embolization is the therapy of choice for recurrent peptic ulcer bleeding refractory to standard endoscopic hemostatic techniques. It offers a minimally invasive approach with high efficacy, lower mortality, and complication rates compared to surgery. However, rare adverse events attributed to coil migration including pulmonary embolism, stroke, myocardial infarction, and bowel obstruction have been reported.

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Article Synopsis
  • The study examined thyroid cancer cases at a hospital in Najran, Saudi Arabia, involving 279 patients from 2014 to 2021, primarily affecting women with a mean age of 42.8 years.
  • Most patients (60.9%) underwent total thyroidectomy, with a significant number showing localized disease; papillary and follicular cancers were the most common types.
  • Independent factors influencing mortality included older age, diabetes, certain cancer subtypes, and metastatic disease, with particularly high risks associated with tumor size and pulmonary metastasis.
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  • * A study of 108 adult Yemeni HF patients revealed that 60.2% had ID, 59.3% had anemia, and 40.7% had both conditions simultaneously, indicating a significant prevalence of ID in this population.
  • * Analysis showed that factors like advanced HF severity, the presence of anemia, and a low ejection fraction were strong predictors of ID, suggesting that iron status checks should be standard for CHF patients to improve recognition and treatment.
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Article Synopsis
  • * A literature search identified 95 relevant studies, revealing difficulties in diagnosing lean MASLD using traditional methods and highlighting the role of advanced imaging techniques.
  • * The study recommends increased clinical awareness, regular monitoring, and tailored management strategies, such as lifestyle changes and potential medications, while calling for more research to improve diagnosis and treatment options.
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Metabolic dysfunction-associated steatotic liver disease (MASLD) poses a major global health challenge. glucagon-like peptide-1 receptor agonists (GLP-1RAs) have shown potential therapeutic benefits for MASLD patients, including improvements in liver function, inflammation, and fibrosis. This study aims to systematically review and meta-analyze randomized controlled trials (RCTs) to evaluate the efficacy and safety of GLP-1RAs in MASLD patients, focusing on hepatic outcomes, cardiovascular outcomes, anthropometric measurements, and mortality.

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This report presents a rare case of acute bacterial native valve endocarditis caused by in a 57-year-old male with a history of intravenous drug use. The patient presented with chest pain, productive cough, and diarrhea, with clinical evaluation revealing atrial flutter, pulmonary embolism, and a large tricuspid valve vegetation. Blood cultures confirmed , an organism rarely implicated in human infections.

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Background: Sympathomimetic vasopressors may be administered through a peripheral catheter, but there are limited data available on the safety of peripheral use.

Objective: The purpose of this study was to analyze the safety of peripherally infused sympathomimetic vasopressors.

Methods: A multicenter, retrospective observational study was conducted to evaluate patients who received peripheral vasopressors.

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Sex disparities in outcomes of transcatheter aortic valve implantation- a multi-year propensity-matched nationwide study.

Int J Cardiol

January 2025

Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA; Division of Cardiology, Department of Medicine, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT, USA.

Article Synopsis
  • This study looked at how men and women do after a heart procedure called TAVI, which helps with a problem called aortic stenosis.
  • It found that women faced more serious complications right after the procedure, like higher chances of dying and having strokes, compared to men.
  • However, men had a higher chance of needing to go back to the hospital within 30 and 90 days after the procedure, but both men and women got better faster from 2016 to 2020.
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Article Synopsis
  • - The neonatal Fc receptor (FcRn) plays a key role in transporting and protecting IgG antibodies, and researchers are exploring the potential of FcRn inhibitors to treat various immune-related diseases.
  • - Studies indicate that FcRn inhibitors can effectively lower total IgG levels without affecting its production or the levels of other antibody types, showing promise as a safer alternative to existing immunosuppressive therapies.
  • - More extensive clinical trials with diverse patient groups are needed to confirm the effectiveness and safety of FcRn inhibitors before they can become standard treatment options for hematologic conditions related to IgG antibodies.
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New graduate nurses are an untapped population for nursing professional governance and nursing research and evidenced-based practice councils. New graduate nurses can offer new insights into the management of patient care and nursing workflow. By educating new graduate nurses about the benefits of nursing research and evidence-based practice councils at the start of their careers, an early standard of excellence in the empowerment of applying evidenced-based practice principles to improve patient care quality can occur.

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Article Synopsis
  • This study looked at patients with liver cirrhosis at a hospital in Ghana to understand how the disease affects their stomach and esophagus.
  • They found that many patients had symptoms like tiredness and swelling, with most being older men in a severe stage of the disease.
  • The most common issue spotted during examinations was esophageal varices, which are bulging veins related to the condition, along with other stomach problems.
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Short term outcomes and resource utilization in versus acute on chronic heart failure related cardiogenic shock: a nationwide analysis.

Front Cardiovasc Med

September 2024

Section of Cardiovascular Medicine, Department of Internal Medicine, Yale New Haven Hospital, New Haven, CT, United States.

Background: There has been growing recognition of non-ischemic etiologies of cardiogenic shock (CS). To further understand this population, we aimed to investigate differences in clinical course between acute on chronic heart failure related (CHF-CS) and de-novo CS (DN-CS).

Methods: Using the Nationwide Readmission Database, we examined 92,426 CS cases.

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Article Synopsis
  • Fibroblast activation protein (FAP) is found in cancer-associated fibroblasts and is linked to poor cancer outcomes; PET/CT imaging using FAPI (radiolabeled FAP inhibitors) is being explored for diagnosing various cancers.
  • FAPI PET/CT outperforms F-fluorodeoxyglucose ([F]FDG) in many cases due to better tumor-to-background contrast, improved specificity for certain metastases, and enhanced sensitivity for identifying disease spread.
  • Despite its advantages, FAPI has challenges such as non-specific uptake in some situations, variations with age/menopause, limited clinical accessibility, and a lack of extensive clinical data supporting its use.
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Background: Recipient functional status prior to transplantation has been found to impact post-transplant outcomes in heart, liver and kidney transplants. However, information on how functional status, before and after transplant impacts post-transplant survival outcomes is lacking.

Aim: To investigate the impact of recipient functional status on short and long term intestinal transplant outcomes in United States adults.

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Background: The ICE3 trial evaluated the safety and efficacy of cryoablation in women aged ≥60 years with low-risk, early-stage breast cancers, aiming to provide a non-operative treatment option and avoid potential surgical risks. This study presents 5-year follow-up trial results.

Methods: The ICE3 trial is an Institutional Review Board-approved, prospective, multicentered, non-randomized trial including women ≥ 60 years of age with unifocal, ultrasound visible, invasive ductal carcinoma ≤ 1.

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