5 results match your criteria: "Bremen Central Hospital[Affiliation]"

Time-Dependent Molecular Motifs of Pulmonary Fibrogenesis in COVID-19.

Int J Mol Sci

January 2022

Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), 30625 Hannover, Germany.

Article Synopsis
  • COVID-19 survivors exhibit a higher risk of pulmonary fibrosis, but the specific molecular processes behind this condition remain unclear.* -
  • In a study involving 12 COVID-19 patients who died from respiratory failure, researchers analyzed gene expression profiles compared to 11 healthy individuals to understand how pulmonary fibrosis develops over time.* -
  • Findings indicate that after the first week of hospitalization, patients shift from inflammation-related gene activity to fibrosis-related gene activity, suggesting potential targets for future treatment.*
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In Germany some 2 000 children and adolescent are diagnosed with cancer every year. Curing rates are increasing and therewith also the number of survivors is growing. Survivors frequently suffer from long-term effects of the disease and its treatment, but long-term follow-up care shows deficits.

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Pathology of tracheal tumors.

Thorac Surg Clin

February 2014

Institute of Pathology, Bremen Central Hospital, St. Juergen-Strasse 1, Bremen 28177, Germany. Electronic address:

Malignant involvement of the trachea predominantly results from direct spread of neighboring tumors to the tracheal wall. Primary tracheal malignancies show a low incidence of approximately 0.1 in every 100,000 persons per year, squamous cell carcinomas and adenoid cystic carcinomas accounting for about two-thirds of adult primary tracheal tumors.

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Cloning of the gene encoding the decorin-binding protein B (DbpB) in Borrelia burgdorferi sensu lato and characterisation of the antibody responses to DbpB in Lyme borreliosis.

J Med Microbiol

August 2002

*Hospital for Children and Adolescents, University of Helsinki, Stenbäckinkatu 11, FIN-00290 Helsinki, †Department of Bacteriology and Immunology, Haartman Institute, Haartmaninkatu 3, FIN-00290 Helsinki, ‡Laboratory Diagnostics, Helsinki University Central Hospital, Haartmaninkatu 3, FIN-00290 Helsinki, §Department of Otorhinolaryngology, University of Helsinki, 00290 Helsinki, Finland and Professor- Hess-Children's Hospital, Bremen Central Hospital, 28205 Bremen, Germany.

A genome walking technique was applied to borrelial DNA to clone the gene encoding decorin-binding protein B (DbpB) in Borrelia garinii and B. afzelii. Sequence analysis showed 62-67% identity of the predicted amino acid sequences of DbpB between the B.

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