5 results match your criteria: "Breast and Thyroid Surgery Graduate School of Medical and Dental Sciences Kagoshima University[Affiliation]"
Background: Pancreatic ductal adenocarcinoma (PDAC) has a high mortality rate owing to its late diagnosis and aggression. In addition, there are relatively few minimally invasive screening methods for the early detection of PDAC, making the identification of biomarkers for this disease a critical priority. Recent studies have reported that microRNAs in extracellular vesicles (EV-miRs) from bodily fluids can be useful for the diagnosis of PDACs.
View Article and Find Full Text PDFEvaluation of laparoscopic cholecystectomy using indocyanine green cholangiography including cholecystitis: A retrospective study.
Medicine (Baltimore)
July 2018
Department of Surgery, JA Kagoshima Kouseiren Hospital Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical and Dental Sciences Kagoshima University, Sakuragaoka, Kagoshima, Japan.
Article Synopsis
- Intraoperative cholangiography using fluorescent indocyanine green (ICG) enhances the identification of biliary anatomy during laparoscopic cholecystectomy (LC), particularly in patients with cholecystitis.
- In a study of 65 patients, ICG cholangiography successfully identified the cystic duct (CD) in 83.1% of cases, while those with identified CD showed significantly higher fluorescence intensity than those who were not identified.
- The study found that patients without identified CD had a higher incidence of acute cholecystitis and conversion to open surgery, indicating that inflammation impacts CD identification, but ICG could improve surgeon confidence even in complicated cases.
Expression of Maternal Embryonic Leucine Zipper Kinase (MELK) Correlates to Malignant Potentials in Hepatocellular Carcinoma.
Anticancer Res
October 2016
Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical and Dental Sciences Kagoshima University, Kagoshima, Japan.
Background/aim: Maternal embryonic leucine zipper kinase (MELK) is categorized as a member of AMP-activated protein kinase families. Various MELK-associated cellular and biological processes affect multiple stages of tumorigenesis. The aim of the present study was to clarify the relationship between MELK expression and hepatocellular carcinoma (HCC) clinicopathological features.
View Article and Find Full Text PDFThe Evaluation of Liver Function and Surgical Influence by ICGR15 after Chemotherapy for Colorectal Liver Metastases.
J Cancer
April 2016
1. Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical and Dental Sciences Kagoshima University, Sakuragaoka 8-35-1 Kagoshima, 890-8520, Japan.
Background; Approximately 60% of patients with colorectal cancer develop liver metastasis at some point after diagnosis. The aim of this study is to investigate whether the evaluation of ICGR15 preoperatively is a useful clinical indicator of hepatic injury following chemotherapy and to investigate the influence of multiple chemotherapies on liver function. Results; Mean ICGR15 values were higher in patients ≥65 years (P = 0.
View Article and Find Full Text PDFProblems of Long Survival Following Surgery in Patients with NonBNonC-HCC: Comparison with HBV and HCV Related-HCC.
J Cancer
April 2015
1. Department of Digestive Surgery, Breast and Thyroid Surgery Graduate School of Medical and Dental Sciences Kagoshima University, Sakuragaoka 8-35-1 Kagoshima, 890-8520, Japan.
Background: The number of patients with hepatocellular carcinoma (HCC) in the absence of both hepatitis B virus surface antigen (HBsAg) and hepatitis C virus antibody (HCVAb) (NBNC-HCC) has been rapidly increasing in Japan. The objective of this study was to compare the clinical and pathological characteristics between patients with the NBNC-HCC, those with HBsAg positive HCC (B-related HCC) and HCVAb positive HCC (C-related HCC). A better understanding will facilitate the development of postoperative strategies to better manage patients with NBNC-HCC.
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