Self-Reported Dyspnea Is Associated with Reduced Health-Related Quality of Life in Quaternary Hospital Workers 1 Year Post Mild COVID-19 Infection.

Background/objectives: The COVID-19 pandemic had significant implications for healthcare workers (HWs), especially those that work in hospitals. This study evaluated health related quality of life (HRQOL) and its relationship with dyspnea approximately one year after COVID-19 infection in HWs.

Methods: HWs with previous COVID-19 infections were interviewed, and the EuroQol five-dimensional three-level questionnaire (EQ-5D-3L) with a visual analog scale (VAS) was used to evaluate HRQOL.

Effectiveness of Leisure-Focused Occupational Therapy Interventions in Middle-Aged and Older People with Mild Cognitive Impairment: A Systematic Review.

This systematic review aimed to evaluate and synthesize scientific evidence on occupational therapy (OT) interventions focused on leisure activities to improve activities of daily living (ADLs) and cognitive function in middle-aged and older people with mild cognitive impairment (MCI). A systematic review was carried out following the guidelines established by the PRISMA statement. The study was registered in the PROSPERO database.

Chitosan Nanoparticle-Mediated Delivery of R.Br. Root Methanolic Extract: A Promising Strategy for Breast Cancer Therapy in DMBA-Induced Breast Cancer in Sprague Dawley Rats.

R.Br., a plant native to the Western Ghats, is recognized for its diverse medicinal properties.

Therapeutic Potential of Dimethyl Fumarate for the Treatment of High-Fat/High-Sucrose Diet-Induced Obesity.

Obesity is characterized by an imbalance between energy intake and expenditure that triggers abnormal growth of adipose tissues. Dimethyl fumarate (DMF) and its primary active metabolite, monomethyl fumarate (MMF), are Nrf2 activators and have been recognized as strategic antioxidants. This study aimed to evaluate the potential of MMF and DMF to interfere with adipogenesis and obesity, and identify the molecular mechanisms involved.

Modulatory Effects of Photobiomodulation on Oxidative and Inflammatory Responses in a Murine Model of Periodontitis.

Periodontitis, an oral disease initiated by a dysbiotic dental biofilm, has an unclear response to photobiomodulation (PBM) as an adjunctive treatment. This study investigates the effects of PBM on reactive oxygen species (ROS), apoptosis, oxidative stress, and inflammatory markers in a periodontitis model using C57BL/6 mice, divided into four groups: control (C), control + PBM (C + PBM), periodontitis (P), and periodontitis + PBM (P + PBM). An infrared diode laser (808 nm, 133.

Combined Association of Plasma Metabolites with Body Mass Index and Physical Activity Level.

Metabolomic analysis of the changes in plasma metabolites in obesity along with physical activity interaction may contribute to disease diagnosis and treatment. We sought to make a comprehensive assessment of the plasma metabolite profile of subjects with a lean ( = 20, BMI = 22.3) or overweight/obese ( = 29, BMI = 29) body mass index (BMI) and low ( = 33, IPAQ = 842) or high ( = 16, IPAQ = 6935) index of physical activity questionnaire (IPAQ), using an untargeted metabolomic approach.

Maternal Low-Protein Diet During Nursing Leads to Glucose-Insulin Dyshomeostasis and Pancreatic-Islet Dysfunction by Disrupting Glucocorticoid Responsiveness in Male Rats.

Both perinatal malnutrition and elevated glucocorticoids are pivotal triggers of the growing global pandemic of metabolic diseases. Here, we studied the effects of metabolic stress responsiveness on glucose-insulin homeostasis and pancreatic-islet function in male Wistar offspring whose mothers underwent protein restriction during lactation. During the first two weeks after delivery, lactating dams were fed a low-protein (4% protein, LP group) or normal-protein diet (22.

Trophic Structure and Isotopic Niche of Invaded Benthic Communities on Tropical Rocky Shores.

When a species is introduced in a new location, it is common for it to establish itself when it finds favorable conditions in the receptor community with regard to interspecific interactions with native species. The azooxanthellate corals coccinea and are invasive species introduced in the Caribbean Sea, the Gulf of Mexico, and the Brazilian Southwest Atlantic. They are successful competitors for space, have multiple reproductive modes, and have high larval dispersion and recruitment, but studies on food and trophic relationships of the genus are still scarce.

(A.ST. Hil.) Saff.: Neuroprotective Effect on Chemically Induced Amnesia, Anxiolytic Effects and Preclinical Safety Evaluation in Mice.

, "araticum-seco", is known to contain several bioactive compounds that can mitigate oxidative stress and act on the central nervous system (CNS). This effect is partly attributed to its potent antioxidant and acetylcholinesterase (AChE) inhibitors. In this study, the effects were explored of the methanolic extract (MEDF) and alkaloid fraction (AFDF) of (leaves) on cognitive behaviors in male mice with scopolamine (Scop)-induced cognitive impairment and biochemical parameters.

Intermediate and Transitory Inflammation Mediate Proper Alveolar Bone Healing Outcome in Contrast to Extreme Low/High Responses: Evidence from Mice Strains Selected for Distinct Inflammatory Phenotypes.

Alveolar bone healing is influenced by various local and systemic factors, including the local inflammatory response. This study aimed to evaluate the role of inflammatory responsiveness in alveolar bone healing using 8-week-old male and female mice (N = 5/time/group) strains selected for maximum (AIRmax) or minimum (AIRmin) acute inflammatory response carrying distinct homozygous RR/SS genotypes, namely AIRminRR, AIRminSS, AIRmaxRR, and AIRmaxSS mice. After upper right incisor extraction, bone healing was analyzed at 0, 3, 7, and 14 days using micro-computed tomography, histomorphometry, birefringence, immunohistochemistry, and PCRArray analysis.

Physiological Stress Response and Oxidative Status in Tambaqui () Fed Diets Supplemented with Selenium.

The present study aimed to evaluate the physiological responses to transport stress in juvenile tambaqui () fed a diet supplemented with hydroxy-selenomethionine (OH-SeMet; Selisseo, Adisseo) and determine through stress biomarkers whether selenium supplementation could reduce the impact of transport stress on tambaqui resilience. Juvenile fish (15.71 ± 1.

Analysis of Growth Models in Galician × Nelore Crossbred Cattle in the First Year of Life.

The veal niche market is gaining momentum in Brazil. Locally known as 'Vitelão', veal refers to the meat from calves slaughtered up to 12 months of age. In this study, we assessed the Galician Blond × Nelore cross as a candidate to produce veal.

Additives in Supplements for Grazing Beef Cattle.

Pasture-based beef cattle production systems aim to maximize the interaction between forage and supplements to increase activity. In addition, supplementation and the use of food additives help optimize production efficiency and improve the use of additional nutrients. The aim of this study was to evaluate the effects of the use of additives in protein-energy supplements (PESs) on the intake, digestibility, and ruminal parameters of beef cattle raised on pasture in the rearing phase.

Exploring Feed Efficiency in Beef Cattle: From Data Collection to Genetic and Nutritional Modeling.

Increasing feed efficiency in beef cattle is critical for meeting the growing global demand for beef while managing rising feed costs and environmental impacts. Challenges in recording feed intake and combining genomic and nutritional models hinder improvements in feed efficiency for sustainable beef production. This review examines the progression from traditional data collection methods to modern genetic and nutritional approaches that enhance feed efficiency.

Bridging the Gap Between Computational Efficiency and Segmentation Fidelity in Object-Based Image Analysis.

A critical issue in image analysis for analyzing animal behavior is accurate object detection and tracking in dynamic and complex environments. This study introduces a novel preprocessing algorithm to bridge the gap between computational efficiency and segmentation fidelity in object-based image analysis for machine learning applications. The algorithm integrates convolutional operations, quantization strategies, and polynomial transformations to optimize image segmentation in complex visual environments, addressing the limitations of traditional pixel-level and unsupervised methods.

Characterization of Three Novel Papillomavirus Genomes in Vampire Bats ().

Bats are mammals with high biodiversity and wide geographical range. In Brazil, three haematophagous bat species are found. is the most documented due to its role as a primary host of rabies virus in Latin America.

Heat Stress in Japanese Quails (): Benefits of Phytase Supplementation.

In tropical and subtropical climate regions, heat stress is one of the main causes of production losses in laying quails, aggravated by the antinutritional effects of the phytate in diet ingredients, which negatively affect the bioavailability of minerals, especially calcium and phosphorus. This situation results in a reduction in production and the quality of eggs from commercial laying quails. Several nutritional strategies are utilized to reduce the adverse effects of high temperatures and antinutritional factors such as phytate.

Effects of Isoflavone Intake on Energy Requirement, Satiety, and Body Composition of Neutered Adult Cats.

Isoflavones are composed of phytoestrogens (genistein and daidzein), which can be metabolized by cats. These compounds can promote the maintenance of lean body mass and control food intake. These effects are desirable in neutered animals, as they are predisposed to obesity.

Drivers of Seasonal Change of Avian Communities in Urban Parks and Cemeteries of Latin America.

Urban parks and cemeteries constitute hot spots of bird diversity in urban areas. However, the seasonal dynamics of their bird communities have been scarcely explored at large scales. This study aims to analyze the drivers of urban bird assemblage seasonality in urban parks and cemeteries comparing assemblages during breeding and non-breeding seasons in the Neotropical Region.

The Effects of a Blend of Essential Oils in the Milk of Suckling Calves on Performance, Immune and Antioxidant Systems, and Intestinal Microbiota.

The objective of the present study was to determine whether the addition of a blend based on the essential oils of cinnamon, oregano, and eucalyptus to the liquid diets of calves would stimulate the immune system combined with anti-inflammatory action, minimize oxidative responses, and alter the intestinal microbiota, consequently enhancing animal growth. Twenty-four male Holstein calves (approximately five days old) were suckled for 60 days, underwent a weaning process, and were followed up until day 75 of the experiment. The calves were divided into control ( = 12) and phytobiotic ( = 12) groups, receiving commercial milk replacer and pelleted concentrate ad libitum.

Generational Differences in Self-Esteem and Vocal Perception Among Brazilian Gay Men.

Introduction: Self-esteem and vocal perception are central aspects of identity and self-presentation, particularly within marginalized communities where voice and self-concept can be deeply intertwined with social acceptance and cultural dynamics. Among Brazilian gay men, generational differences in these areas may reflect broader social changes, shifts in stigma, and evolving notions of masculinity. This study aims to explore these differences, examining how self-esteem and self-assessed vocal descriptions vary across generations, thereby shedding light on specific needs and areas for potential support within these communities.

Prevalence of sensory impairments and its contribution to functional disability in individuals with acute stroke: A cross-sectional study.

Background: Although the literature suggests high prevalences of sensory impairments after stroke, the independent contribution of sensory modalities to functionality needs further investigation.

Objective: To identify the prevalence and characterize the sensory impairment in adults with stroke and to verify the contribution of proprioceptive and exteroceptive impairments to their functional disability.

Methods: Exploratory cross-sectional study conducted in a hospital stroke unit.

The impact of mechanical insufflation-exsufflation on the weaning success rate of tracheostomized patients on prolonged mechanical ventilation: a pilot and feasibility study of a randomized controlled trial.

Objective: To evaluate the feasibility of adding mechanical insufflation-exsufflation (MI-E) to a weaning protocol for tracheostomized patients undergoing prolonged mechanical ventilation (MV).

Design: Single-center, open-label, randomized, controlled pilot and feasibility study.

Setting: Intensive care unit in Brazil.

Impact of the resin cement opacity on the final color of conservative ceramic restorations and on its ability to mask substrates of different saturations.

Objective: To analyze the impact of the translucency/opacity of two commercial brands of resin cements and different translucency of lithium disilicate on the masking ability of saturated substrates.

Methods: 120 samples (n = 5) were prepared using 0.5 mm lithium disilicate (IPS e.

Postvoid Residual Volume Correlates With Bladder Outlet Obstruction and Not With Detrusor Contraction Strength Parameters in Women: A Matched Case-Control Study.

Purpose: To compare voiding parameters in women with and without increased postvoid residual (PVR) volume, to correlate these parameters with PVR volume and PVR percentage, and to describe their ability to predict an increased PVR volume.

Methods: Retrospective cross-sectional study of urodynamics data prospectively acquired from consecutive symptomatic women over a 5-year period. Patients with spinal cord disorders and with abdominal straining during voiding (abdominal pressure ≥10 cm H2O over baseline at maximum flow rate [Qmax]) were excluded.