Advances in intraoperative imaging in retinal diseases: A narrative review.

This review explores recent technological advances in intraoperative imaging during retinal disease surgeries, focusing on their applicability in clinical practice and impact on surgical outcomes. A literature search identified studies discussing new imaging technologies, their advantages over conventional methods, relevant case studies, and literature reviews. Exclusion criteria included studies unrelated to retinal diseases, imaging technologies not suitable for intraoperative use, outdated articles, and nonscientific reports.

Regional-specific trends of PM and O temperature sensitivity in the United States.

Climate change poses direct and indirect threats to public health, including exacerbating air pollution. However, the influence of rising temperature on air quality remains highly uncertain in the United States, particularly under rapid reduction in anthropogenic emissions. Here, we examined the sensitivity of surface-level fine particulate matter (PM) and ozone (O) to summer temperature anomalies in the contiguous US as well as their decadal changes using high-resolution datasets generated by machine learning.

A human skin-on-a-chip platform for microneedling-driven skin cancer treatment.

Skin-on-a-chip models provide physiologically relevant platforms for studying diseases and drug evaluation, replicating the native skin structures and functions more accurately than traditional 2D or simple 3D cultures. However, challenges remain in creating models suitable for microneedling applications and monitoring, as well as developing skin cancer models for analysis and targeted therapy. Here, we developed a human skin/skin cancer-on-a-chip platform within a microfluidic device using bioprinting/bioengineering techniques.

Comprehensive molecular epidemiology of influenza viruses in Brazil: insights from a nationwide analysis.

Influenza A and B viruses represent significant global health threats, contributing substantially to morbidity and mortality rates. However, a comprehensive understanding of the molecular epidemiology of these viruses in Brazil, a continental-size country and a crucial hub for the entry, circulation, and dissemination of influenza viruses within South America, still needs to be improved. This study addresses this gap by consolidating data and samples across all Brazilian macroregions, as part of the Center for Viral Surveillance and Serological Assessment project, together with an extensive number of other Brazilian sequences provided by a public database during the epidemic seasons spanning 2021-23.

EVALUATION OF IDIOPATHIC SCOLIOSIS IN SUBTYPES OF PECTUS EXCAVATUM AND CARINATUM.

Objective: Evaluation of epidemiological data on Idiopathic Scoliosis in patients with different pectus subtypes.

Methods: A medical record analysis of 418 patients with pectus, associated with idiopathic scoliosis above 10°, with research on: subtypes of pectus (Lateral Pectus Carinatum, Inferior Pectus Carinatum, Superior Pectus Carinatum, Broad Pectus Excavatum, and Localized Pectus Excavatum), and characteristics of the scoliotic curve (Cobb angle, laterality, and location).

Results: The mean age was 14.

ASSESSMENT OF SATISFACTION IN PATIENTS UNDERGOING SURGICAL TREATMENT BY THE WALANT TECHNIQUE.

Objective: To analyze the satisfaction of patients who underwent hand surgical treatment with the wide-awake local anesthesia no tourniquet (WALANT) anesthesia technique.

Methods: This is a cross-sectional study on the satisfaction of patients who underwent hand surgical treatment with the WALANT technique. These patients were treated at the Hand and Microsurgery outpatient clinic of a public hospital from March 2020 to March 2022.

W-SITTING IN CHILDHOOD: A SYSTEMATIC REVIEW.

Objective: Despite the lack of science-based evidence, many specialists and non-specialists consider W-sitting detrimental to children. This systematic review aims to find evidence on W-sitting.

Methods: This review was registered on PROSPERO under the number CRD42022313341.

ENDOSCOPIC SURGERY FOR TREATING SPINAL STENOSIS: AN INTEGRATIVE REVIEW OF RANDOMIZED CLINICAL TRIALS.

Background: Spinal stenosis refers to the narrowing of the spinal canal which can generate clinical symptoms secondary to the spinal cord injury itself, or even root involvement. The traditional open surgical procedure to correct spinal stenosis is highly traumatic and risky, and with the development of surgical techniques, endoscopic procedures have been widely used in treating said stenosis, achieving good results with minimally invasive management.

Aim: To conduct a literature review regarding endoscopic techniques for correcting spinal stenosis.

INCREASED INCIDENCE OF INJURIES IN THE SÃO PAULO SOCCER CHAMPIONSHIP POST-PANDEMIC.

Objective: Soccer shows a high incidence of injuries and its cause is multifactorial. The impacts of the coronavirus pandemic are unknown. This study aims to evaluate the incidence of injuries in the 2023 Campeonato Paulista de Futebol (São Paulo Soccer Championship) and compare it to the championships prior to the pandemic.

SHOULDER PAIN, ULTRASOUND CHANGES, AND FUNCTIONAL PERFORMANCE IN OBESE PATIENTS.

Objective: To evaluate the prevalence of shoulder pain, level of functional performance, and morphological involvement of the rotator cuff on ultrasound in morbidly obese patients.

Methods: The study included 54 morbidly obese patients receiving follow-up care in a bariatric surgery outpatient clinic, which were compared with a control group consisting of 49 participants. Presence of shoulder pain, shoulder functional performance, ultrasound of the rotator cuff and blood tests were the parameters evaluated.

EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH ANKLE FRACTURE TREATED IN A TERTIARY LEVEL HOSPITAL.

Objective: To evaluate the epidemiological profile of patients diagnosed with ankle fracture admitted to a tertiary hospital.

Methods: Retrospective Cross-Sectional Observational Study.

Inclusion Criteria: Individuals aged ≥18 (eighteen) years, diagnosed with ankle fracture, who underwent surgical and/or conservative treatment at a tertiary hospital in the city of São Paulo.

TREATMENT OF ADHESIVE CAPSULITIS WITH THE TRIPLE PROCEDURE: INTRA-ARTICULAR INJECTION WITH CORTICOSTEROIDS, HYDRODILATION AND SHOULDER MANIPULATION UNDER SEDATION.

Objective: There are several conservative treatment options for adhesive capsulitis (AC), but no previous study combines hydrodilation, corticosteroid injection and joint manipulation under sedation (triple procedure), followed by daily home exercises.

Methods: Patients included were evaluated before the procedure, at 30 days, 3, 6 and 12 months after treatment in prospective cohort. The outcomes used were the ASES, UCLA, SANE, VAS scales and passive range of motion (ROM).

INJURIES DURING THE COVID-19 PANDEMIC IN THE 2021 PAULISTA SOCCER CHAMPIONSHIP IN BRAZIL.

Objective: To assess the incidence and characteristics of injuries that occurred during the 2021 season of the Paulista Soccer Championship during the coronavirus disease 2019 pandemic and to compare these characteristics before and after the championship interruption.

Methods: A prospective study was conducted using an electronic form developed by the Medical Committee of the Paulista Soccer Federation. The results were sent by the team physicians of Series A1 after each round of the Paulista Soccer Championship.

GAIT ASSESSMENT IN ANKLE FRACTURES WITH SYNDESMOSIS LESIONS UNDERGOING SURGERY.

Introduction: The three-dimensional evaluation of patients in the gait laboratory is a diagnostic method that is gaining ground in various orthopedic pathologies and, in the case of ankle fractures, can more accurately detail the degree of joint limitation.

Objective: To present the importance of laboratory gait studies in the postoperative period of ankle fractures associated with syndesmosis ligament injuries, increasing the arsenal for assessing whether the surgical approach and outcome were satisfactory.

Methods: Case series of 13 patients who underwent surgical treatment for ankle fractures associated with syndesmosis injuries, evaluated postoperatively in the gait clinic using the BTS GAITLAB hardware program.

Vole hunting: novel predatory and carnivorous behavior by California ground squirrels.

Unlabelled: Dietary flexibility allows animals to respond adaptively to food pulses in the environment. Here we document the novel emergence of widespread hunting of California voles and carnivorous feeding behavior by California ground squirrels. Over two months in the twelfth year of a long-term study on the squirrel population, we document 74 events of juvenile and adult ground squirrels of both sexes depredating, consuming, and/or competing over vole prey.

Surface Roughness and Color Stability of Conventional and Bulk-Fill Resin Composite with S-PRG Fillers After Coffee Exposure: An in-vitro Study.

Objective: This study aimed to evaluate the in vitro effects of coffee exposure on the color and roughness of conventional and bulk-fill resin composites, with and without surface pre-reacted glass-ionomer (S-PRG) filler.

Methodology: Forty-eight cylindrical samples (Ø6 mm × 2 mm) were prepared and categorized as follows (n = 12 per group): conventional nano-hybrid (Tetric N-Ceram, Ivoclar); nano-hybrid with S-PRG filler (Beautifil II, Shofu); bulk-fill (Tetric N-Ceram Bulk Fill, Ivoclar); and bulk-fill with S-PRG filler (Beautifil Bulk Restorative, Shofu). The samples were assessed for surface roughness (Ra, μm), color coordinates (CIE Lb), and overall color change (ΔE, ΔE).

Valosin-containing protein (VCP), a component of tumor-derived extracellular vesicles, impairs the barrier integrity of brain microvascular endothelial cells.

Metastases are the leading cause of cancer-related deaths, and their origin is not fully elucidated. Recently, studies have shown that extracellular vesicles (EVs), particularly small extracellular vesicles (sEV), can disrupt the homeostasis of organs, promoting the development of a secondary tumor. However, the role of sEV in brain endothelium and their association with metastasis related to breast cancer is unknown.

Assessing the prevalence of neutralizing antibodies (NAbs) to SARS-CoV-2 during three years of the COVID-19 pandemic.

The development of COVID-19 vaccines has been an important step in the fight against the pandemic. However, it is still necessary to understand the influence of factors that can alter the immune response. In general, doses need to be updated frequently, and care must be taken to control the virus that is still circulating worldwide.

Risk Factors for Mortality after Out-of-hospital Resuscitation are More Diverse than Assumed.

Finsterer J, Scorza CA, Scorza FA, Fiorini AC. Risk Factors for Mortality after Out-of-hospital Resuscitation are More Diverse than Assumed. Indian J Crit Care Med 2025;29(1):92-93.

Persistent Mortality Risk From Device-related Healthcare-associated Infection in Kidney Transplant Recipients Despite Multifaceted Interventions Action Calls for a Zero-tolerance Policy.

Background: Although multifaceted control intervention actions (bundles) are highly effective in reducing the risk of device-related healthcare-associated infections (d-HAIs), no studies have explored their impact on the outcomes of kidney transplant recipients (KTRs) or the extent of risk reduction achievable through the bundle implementation.

Methods: Seven hundred ninety-eight prevalent KTRs admitted to the intensive care unit (ICU) requiring invasive devices were included: 449 patients from the bundle preimplementation period and 349 from the postimplementation period. The primary outcome was mortality within 90 d of ICU admission.

A morpho-histological analysis of the exoskeleton of (Cnidaria, Hydrozoa) reveals insights into the taxonomy of Clathrozoellidae and Hydroidolina.

The taxonomic complexity of the families Clathrozoidae and Clathrozoellidae, rooted in early 20th-century hydroid descriptions, highlights the need for comprehensive and detailed morphological analyses. This study aimed to elucidate the histology of the polypoid stage of Peña Cantero, Vervoort & Watson, 2003, with a particular emphasis on its exoskeletal structure. Specimens from the National Museum of Natural History were examined histologically using different staining techniques.

Reproductive strategies in loggerhead sea turtle : polyandry and polygyny in a Southwest Atlantic rookery.

Sea turtles are highly migratory and predominantly inhabit oceanic environments, which poses significant challenges to the study of their life cycles. Research has traditionally focused on nesting females, utilizing nest counts and mark-recapture methods, while male behavior remains understudied. To address this gap, previous studies have analyzed the genotypes of females and hatchlings to indirectly infer male genotypes and evaluate the extent of multiple paternity within populations.

Novel Therapies to Reduce Rehospitalization Risk in Worsening Heart Failure: Systematic Review and Network Meta-Analysis.

Background: Worsening heart failure (WHF) challenges health care with frequent rehospitalizations and reduced quality of life for patients. Despite therapeutic advances, high rehospitalization risks highlight the urgent need for new treatments.

Objectives: This study evaluated the effectiveness of initiating novel therapies during hospitalization or vulnerable phase for WHF patients to reduce rehospitalization risks and determine the optimal treatment sequence.

Burden of diabetes in correctional facilities: A global systematic review and meta-analysis.

Background: Diabetes mellitus presents significant public health challenges worldwide. While its prevalence and management in the general population have been extensively studied, comprehensive research on diabetes among incarcerated individuals is lacking. This study aims to conduct a systematic review and -analysis to determine the prevalence of diabetes within the prison population.