548,287 results match your criteria: "Brazil; Hypertension League Federal University of Goias[Affiliation]"
Alzheimers Dement
December 2024
Universidade de Sao Pablo, Sao Pablo, Brazil.
Background: Some older adults with subjective decline (SCD) had a positive amyloid biomarker indicating a preclinical stage of Alzheimer's disease.
Objectives: To assess the accuracy of Delayed Recall of Figure Memory Test (DR-FMT) of Brief Cognitive Screening Battery to predict amyloid status in SCD older adults.
Method: The sample consisted of 45 older adults classified as SCD and 25 as cognitively unimpaired (mean age of 76.
Alzheimers Dement
December 2024
University of Pittsburgh, Pittsburgh, PA, USA.
Background: Recent studies showed that neuroinflammation plays a key role in triggering specific neuropsychiatric symptoms (NPS), such as irritability and agitation, in individuals with Alzheimer's disease (AD). While prior studies showed an association between tau pathology and all NPS domains, the extent to which tau influences each specific NPS domain remains unclear. Here, we aim to investigate the association of tau and NPS domains in the AD continuum.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Southern Santa Catarina (UNESC), Criciuma, SC, Brazil.
Background: The population aged 80 or over has increased, which may predispose people to dementia. Validated scales are used to diagnose them. The study aimed to compare cognitive evolution and associated factors in individuals aged 80 or over.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Background: Language impairment manifestations in patients with the semantic variant of primary progressive aphasia (S-PPA) include surface dysgraphia. Word and pseudoword dictation helps characterize errors in these patients' writing to better conduct their therapeutic strategies. Few studies have addressed written language in patients with dementia, and even fewer have done so in PPA.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of São Paulo School of Medicine, São Paulo, São Paulo, Brazil.
Background: Post-COVID19 syndrome is characterized by signs and symptoms that occur within 3 months of the onset of COVID19 acute phase and last at least 2 months. In the past 3 years, cognitive impairment has frequently been associated with COVID19 with descriptions of attentional, executive, memory, and language disorders. Many studies have assessed these cognitive disturbances using online and telephone tests, often in isolated interviews on a cross-sectional design in high-income countries.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Older Adult's Psychiatry and Psychology Extension Program I Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Alzheimers Dement
December 2024
Older Adult's Psychiatry and Psychology Extension Program I Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Alzheimers Dement
December 2024
University of Pittsburgh, Pittsburgh, PA, USA.
Background: Alzheimer's disease (AD) is classically viewed as a predominantly amnestic syndrome, with other cognitive and neuropsychiatric symptoms (NPS) being non-integral associations. Emerging Evidence suggests that within typical AD, these symptoms are core features from the onset.
Methods: We employed K-modes clustering on 2483 cognitively impaired (CI) individuals (CDR ≥ 0.
Alzheimers Dement
December 2024
University of Pittsburgh, Pittsburgh, PA, USA.
Background: The newly proposed criteria by the AA working group incorporates both biological and clinical stages to characterize the progression of AD. In this study, we aim to evaluate the agreement between these two complementary systems.
Methods: Using 188 participants from McGill TRIAD and 139 from the HEAD cohorts, we categorized participants into biological (0-4) and clinical (0-4) stages using amyloid PET, tau PET(MK-6240), and clinical measures as described by the working group.
Alzheimers Dement
December 2024
Sciences Applied to Adult Health Postgraduate Program, School of Medicine, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Background: Short screening tools designed to detect cognitive impairment are important for clinical and research. The Clinical Dementia Rating (CDR) is the main used categorization system, which classifies from no dementia, to questionable dementia/mild cognitive impairment (MCI) and three severities of dementia.
Objective: To conduct an accuracy analysis of different short screening tests to predict CDR scores on a cohort of a Memory Clinic.
Alzheimers Dement
December 2024
Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Background: Language is frequently affected in patients with sporadic amyotrophic lateral sclerosis (sALS), with reduced performance in naming, syntactic comprehension, grammatical expression, and orthographic processing. In a previous study, we demonstrated that the language profile of patients with familial type 8 ALS (ALS8), linked to p.P56S VAPB mutation, is similar to sALS.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
Alzheimers Dement
December 2024
Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
Background: Dementia and cognitive impairment, primarily linked to aging, are increasingly recognized as multifactorial conditions. Emerging research has pointed to early menopause as another potential risk factor. However, its relationship with cognitive impairment needs further investigation, especially in low- and middle-income countries.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
Hum Reprod
January 2025
Pôle de Recherche en Physiopathologie de la Reproduction, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
Ovarian tissue cryopreservation and transplantation has emerged as a promising fertility preservation technique for individuals facing premature ovarian insufficiency due to various medical conditions or treatments. Xenotransplantation, involving the transplantation of ovarian tissue into animal hosts, has played a pivotal role in refining ovarian tissue cryopreservation and transplantation techniques and addressing key challenges. This review provides a comprehensive overview of the current landscape of ovarian tissue xenotransplantation research, focusing on its applications in investigating ovarian biology, optimizing ovarian tissue cryopreservation and transplantation protocols, and assessing safety concerns.
View Article and Find Full Text PDFNeurourol Urodyn
January 2025
Department of Physical Therapy, Universidade Federal de Pernambuco (UFPE), Recife, Pernambuco, Brazil.
Background: Applicability of the virtual games has been increasingly added to rehabilitation treatments, including women's health interventions.
Objective: To develop a virtual interface designed to increase consciousness and relax the pelvic floor muscles, validate its content and appearance, and check the level of usability and satisfaction.
Methods: Physiotherapy specialists with experience in pelvic floor rehabilitation and database research were consulted to define the content.
Am J Primatol
January 2025
Ecology and Animal Behavior Laboratory, Department of Animal and Plant Biology, State University of Londrina, Londrina, Paraná, Brazil.
Tool use to crack open palm nuts has been observed extensively in some capuchin monkey species. However, for southern black-horned capuchin monkeys (Sapajus nigritus cucullatus), there is only one published record of stone tool use from the 1990s, from an urban park in Londrina, Brazil. In the present study, we returned to this urban park to systematically investigate the hammer-and-anvil sites used to crack nuts by this capuchin monkey population.
View Article and Find Full Text PDFFundam Clin Pharmacol
February 2025
Experimental Oncology and Hemopathies Laboratory, Clinical Analysis Department, Federal University of Santa Catarina, Florianópolis, 88040-900, Brazil.
Background: Chalcones have been described in the literature as promising antineoplastic compounds.
Objectives: Therefore, the objective of this study was to analyze the cytotoxic effect of 23 synthetic chalcones on human acute leukemia (AL) cell lines (Jurkat and K562).
Methods: Cytotoxicity assessment was performed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method.
Vet Dermatol
January 2025
Veterinary Institute, Federal Rural University of Rio de Janeiro, Rio de Janeiro, Brazil.
Background: Canine aural cholesteatoma (more appropriately named tympanokeratoma) is an epidermoid cyst whose aetiopathogenesis remains poorly recognised in veterinary medicine. There are a few reports published, possibly because it may be underdiagnosed.
Objectives: To characterise the clinical aspects of dogs with tympanokeratoma, to describe the otoendoscopic, advanced imaging and histopathological findings of tympanokeratoma and to report the best approach to diagnose canine auricular tympanokeratoma in a retrospective study.
Front Comput Neurosci
December 2024
Biomedical Image Processing (BIP) Lab, Department of Computing, Federal University of São Carlos, São Carlos, Brazil.
Front Psychol
December 2024
Research Center in Sports, Health and Human Development, Covilhã, Portugal.
Transl Anim Sci
December 2024
Faculdade de Medicina Veterinária e Zootecnia, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS 79074-460, Brazil.
Two experiments evaluated the effects of an injectable trace mineral (ITM) solution at weaning on trace mineral (TM) status, inflammatory and antioxidant responses, grazing behavior, response to vaccination, and growth of beef calves. Experiment 1 used 86 Nellore calves (40 females and 46 males; body weight [BW] = 198 ± 30.8 kg; 8 ± 1 mo of age) weaned (day 0) and assigned into one of two treatments: saline (0.
View Article and Find Full Text PDFHeliyon
November 2024
Laboratorio de Virus Emergentes/reemergentes. Unidad de Virología, Departamento de Laboratorios de Salud Pública, Portugal.
This study details a genomics-based approach for the early detection of mosquito-borne pathogens, marked by Uruguay's first ever complete genomic sequencing of Dengue Virus type I genotypes I and V. This pioneering effort has facilitated the prompt identification of these genotypes within the country, enabling Uruguayan public health authorities to develop timely and effective response strategies. Further integrated into this approach is a climate-driven suitability measure, closely associated with Dengue case reports and indicative of the local climate's role in the virus's transmission in the country within the changing climate context.
View Article and Find Full Text PDFFront Hum Neurosci
December 2024
Programa de Pós-Graduação em Infectologia e Medicina Tropical, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Introduction: Galvanic vestibular stimulation (GVS) is a simple, safe, and noninvasive method of neurostimulation that can be used to improve body balance. Several central nervous system diseases cause alterations in body balance, including HTLV-1-associated myelopathy (HAM).
Objective: To test GVS as a balance rehabilitation strategy for HAM.
Braz J Vet Med
December 2024
Veterinarian, DSc. DMCV, IV, UFRRJ. Seropédica, RJ, Brazil.
alpha toxin (CPA) is an important enterotoxemic pathogen linked to gastrointestinal disorders and previously associated with pulmonary disease in other mammals. A young female neotropical otter presented with lethargy, anorexia and steatorrhea, which developed within 24 hours. Veterinary care was provided under anesthesia, during which dehydration, intestinal hypermotility and pulmonary crackling sounds were identified.
View Article and Find Full Text PDF