(Platyhelminthes: Monogenea) infecting spp. (Siluriformes: Heptapteridae) in Mexico, and their phylogenetic position within Gyrodactylidea.

Gyrodactylidae Cobbold, 1864 is a monophyletic family of hyperviviparous species, with 36 genera and approximately 700 species. Here, we focused on one of these genera - namely Jara & Cone, 1989 - characterizing its morphological variation systematically and testing its phylogenetic position in relation to other genera in the family. We collected and describe two new species of monogenean parasites of infecting Neotropical freshwater catfishes in Mexico.

Medication experiences in the treatment of opioid use disorders: Insights from Reddit.

Background And Aims: Better understanding the challenges faced by patients on medications for opioid use disorder (MOUD), including methadone and buprenorphine, is critical to increasing their use/retention. Social media platforms such as Reddit offer a space for patients to share their experiences with medications. We aimed to identify and characterize challenges faced by patients taking MOUD through analysis of discussions from the r/Methadone and r/suboxone subreddits.

Potential of enterocin from MF5 in controlling species.

This research paper presents the characterization of an enterocin-producing MF5 isolate and the determination of the in vitro antilisterial activity of enterocin produced by this isolate, named Ent-MF5. PCR-based screening for bacteriocin biosynthetic genes revealed that MF5 harbors multiple enterocin-encoding genes ( A, B, P and X), classified as class II bacteriocins and enterocin-P of (sharing up to 99% similarity at the genetic level). MF5 is sensitive to eight clinically important antibiotics and does not possess cytolysin activator -A, gelatinase -E and hyaluronidase -lA virulence genes.

New Food Ingredients: The Challenge of Potential New Pathogens and Spoilage Issues.

The UN Sustainable Development Goal 2 (Zero Hunger) highlights the need to produce sufficient food commodities to meet the world's population demands and combat hunger, while also respecting the environment and adhering to sustainability principles. Since the beginning of the 21st century, new ideas, ingredients, and technologies have emerged that could significantly transform the food industry. These transformations may alter the rules of food production by integrating traditional knowledge with new technologies and scientific advancements.

Trimethylamine N-Oxide Plasma Levels Following Red Meat and Cod Fish Intake: A Pilot Crossover Trial in Hemodialysis Patients.

Scope: The uremic toxin trimethylamine N-oxide (TMAO) accumulates in patients with chronic kidney disease (CKD) and is associated with its progression, cardiovascular disease, and other complications. The gut microbiota produces TMAO from substrates mainly found in red meat, eggs, and dairy. However, some saltwater fish also contain high levels of TMAO.

Impact of the COVID-19 pandemic on tobacco product consumption and behavioral patterns from a low-middle income country perspective: A qualitative study.

Introduction: Previous studies investigating socioeconomic status and tobacco consumption during the COVID-19 pandemic were survey-based. To extend knowledge beyond prevalence rates and trends of tobacco consumption, qualitative research is needed to identify individual's experiences. There is a critical gap within this context, particularly in low-middle income countries.

Inflammatory and neuropathological responses to encephalitis in adult mice: variability, tolerance and resistance.

(CARV) is a pathogen with neuroinvasive potential, yet its impact on neuroinflammation and sickness behavior remains poorly understood. In this study, we investigated the neuropathological and immunological responses to CARV encephalitis in adult BALB/c mice. Mice were intranasally inoculated with either infected or uninfected brain homogenates, and clinical, histopathological, and cytokine profiles were analyzed.

Global threat status, rarity, and species distribution affect prevalence of Atlantic Forest endemic birds in citizen-collected datasets.

The Atlantic Forest is one of the most threatened biomes globally. Data from monitoring programs are necessary to evaluate the conservation status of species, prioritise conservation actions and to evaluate the effectiveness of these actions. Birds are particularly well represented in citizen-collected datasets that are used worldwide in ecological and conservation studies.

Belonging: a meta-theme analysis of women's community-making in group antenatal and postnatal care.

Health care systems are social institutions simulating microcosms of wider societies where unequal distribution of power and resources translate into inequities in health outcomes, experiences and access to services. Growing research on participatory women's groups positively highlights the influence of group-based care on health and wellbeing for women, their infants, families and wider communities across different countries. With similarities in ethos and philosophies, group care combines relational, group-based facilitation and clinical care, uniquely offering an opportunity to examine the intersections of health and social care.

Sleep quality and duration and frailty in older adults: a systematic review.

Introduction: Sleep problems and frailty are associated with adverse health outcomes in older adults, including mortality, and constitute a major public health challenge.

Objective: This study investigated the association between sleep quality and duration and frailty in older adults, with emphasis on methods of evaluation.

Methods: This systematic review was guided by the Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA).

A global survey about undiagnosed rare diseases: perspectives, challenges, and solutions.

Background: Undiagnosed rare diseases (URDs) are a complex and multifaceted challenge, especially in low-and medium-income countries. They affect individuals with unique clinical features and lack a clear diagnostic label. Although the Undiagnosed Diseases Network International (UDNI) definition of URDs is not universally accepted, it is widely recognized.

Burnout, life satisfaction, and work-related quality of life among psychologists.

Introduction: The Work-Related Quality of Life (WRQoL) is a complex, multidimensional concept, and its assessment is challenging due to a lack of consensus on the factors involved. While the WRQoL Scale has been validated in various countries, no translation into Brazilian Portuguese existed until this study. The primary aim was to validate the Brazilian Portuguese version of the WRQoL Scale, using psychologists as the target population, and to measure burnout and life satisfaction in this group.

Naming, Stimulus Equivalence and Relational Frame Theory: Stronger Together than Apart.

Research on human language started to change when Murray Sidman and colleagues demonstrated that a participant was able to derive unreinforced stimulus relations after conditional discrimination training. This work provided the basis for a novel approach to research on symbolic behavior and fostered the development of three main theoretical accounts: stimulus equivalence (SE), relational frame theory (RFT), and naming theory (NT). These accounts unfolded in the last decades of the twentieth century, promoting intense debate and discussion within behavior analysis.

Muscle loss in cancer cachexia: what is the basis for nutritional support?

Cancer cachexia (CC) is characterized by significant skeletal muscle wasting, and contributes to diminished quality of life, while being associated with poorer response to treatment and with reduced survival. Chronic inflammation plays a central role in driving CC progression, within a complex interplay favoring catabolism. Although cachexia cannot be fully reversed by conventional nutritional support, nutritional intervention shows promise for the prevention and treatment of the syndrome.

Brazilian real-world data of immunotherapy in extensive stage small cell lung cancer.

Introduction: The landmarks of Thoracic Oncology in the last two decades have been accompanied by exponential growth in costs, making it imperative to assess the real benefit of incorporating new technologies. Combining immunotherapy (IO) with platinum-etoposide chemotherapy has become the standard of care in first-line treatment of extensive-stage small cell lung cancer (ES-SCLC). However, the absolute difference in overall survival (OS) has reached three months.

Endovenous Treatment for Great Saphenous Vein Insufficiency: A Comparative Study of Segmental Radiofrequency and 1470-nm Endovenous Laser.

PurposeThis study aims to evaluate recovery time, patient-centric postoperative outcomes, and the efficacy of endovenous laser ablation (LA) and radiofrequency ablation (RFA) in treating venous insufficiency associated with great saphenous vein (GSV) reflux.MethodsIn this single-center, self-paired, randomized trial, 16 limbs from 8 patients with symptomatic bilateral GSV insufficiency were treated. LA was performed on one lower limb, and after 40 days, the contralateral limb was treated with RFA.

Potential Biomarkers Indicating Resistance or Resilience in Experimental Peri-Implant Mucositis: A Systematic Review and Meta-Analysis.

Objectives: To identify changes in immunological, microbiological, and histological biomarkers that may indicate resistance during the induction phase and resilience during the resolution phase of experimental peri-implant mucositis (PiM).

Materials And Methods: The search was performed in MEDLINE, EMBASE, Web of Science, SCOPUS, Cochrane Library, and LILACS databases. Prospective interventional studies assessing biomarkers during experimental PiM were included.

Allergic Reaction to Beta-Glucans in an Obese Dog: A Case Report of Confirmed and Suspected Sources.

Food allergy is defined as an abnormal immune system response to the ingestion of certain ingredients or food additives. Beta-glucans may support the management of obesity, particularly due to their immunomodulatory properties. However, the possible adverse reactions of this nutraceutical are little known.

Notch1 Signalling Is Downregulated by Aerobic Exercise, Leading to Improvement of Hepatic Metabolism in Obese Mice.

Background And Aims: Notch1 protein plays a significant role in hepatic metabolism, as evidenced by its correlation with insulin resistance in the livers of obese individuals, making it an intriguing research target. Therefore, this study aims to investigate the impact of aerobic exercise on Notch1 pathways in the hepatic tissue of obese mice and its role in controlling hepatic metabolism.

Methods: Therefore, we conducted a cross-sectional study utilising liver biopsies from lean and obese humans, as well as an intervention study involving mice subjected to a high-fat diet.

Investigating TikTok Trends in Transcranial Direct Current Stimulation: A Comprehensive Descriptive Analysis.

Background: Transcranial direct current stimulation (tDCS) has gained significant attention in both academic and clinical settings due to its potential benefits in treating various neurological conditions. However, the accessibility and accuracy of information on social media platforms, such as TikTok, can greatly influence public perception and understanding of this technology. Therefore, because the information on the platform is not peer-reviewed, the analysis of the TikTok content is essential for the audience.

One-Dimensional Blood Flow Modeling in the Cardiovascular System. From the Conventional Physiological Setting to Real-Life Hemodynamics.

Research in the dynamics of blood flow is essential to the understanding of one of the major driving forces of human physiology. The hemodynamic conditions experienced within the cardiovascular system generate a highly variable mechanical environment that propels its function. Modeling this system is a challenging problem that must be addressed at the systemic scale to gain insight into the interplay between the different time and spatial scales of cardiovascular physiology processes.

Results of Lisfranc Injuries Treated With Interosseous Suture Button Fixation With a Minimum 5-Year Follow-Up.

Background: Open reduction and internal fixation or primary arthrodesis are considered gold standards for treating Lisfranc injuries. However, several drawbacks are associated with these procedures, such as joint motion loss and potential cartilage damage. More recently, the suture button emerged as an alternative treatment for ligamentous Lisfranc injuries, which can be used either alone or in combination with traditional techniques, with the potential to mitigate some of these potential disadvantages.

Resistivity and Pulsatility Indexes Renal Values Do Not Differ When Obtained from Abdominal or Transrectal Approaches in Healthy Horses.

Early detection of renal deficient function is imperative for the success of treatments and determining prognosis. In horses, a renal ultrasound can be performed through the abdominal wall (TA) or transrectally (TR), being an important tool for the evaluation of the kidneys. Besides renal morphology, resistivity (RI) and pulsatility indexes (PI) may be early tools to detect renal injury as they reflect arterial compliance.

Deciphering the IgG Idiotype Network Through Proteomic Analysis of Potential Targets in SARS-CoV-2-Induced Immune Responses.

The association between COVID-19 and autoimmune diseases has gained increasing recognition, yet the specific targets of SARS-CoV-2-induced IgG are currently in focus for several studies. This study aims to explore the proteomic targets of these antibodies and their potential role in autoimmunity. We utilised a human proteome microarray encompassing 23 736 unique proteins, including isoform variants and fragments, as catalogued by the Human Protein Atlas.