Knowledge and perception of HIV pre-exposure prophylaxis among healthcare workers.

In Brazil, pre-exposure prophylaxis (PrEP) is freely available to individuals at high risk of HIV infection. However, knowledge and perception of PrEP can act as barriers to its access and use. This study evaluated PrEP knowledge and perception among healthcare workers in the Unified Health System in a Brazilian capital.

From surgical problem to surgical solution - lessons and reflections.

In this insightful and personal biographical article, Professor Bertelli recounts his journey from surgical problem to surgical solution with incredible detail. This was an invited article as part of the 2025 Special Issue on 'Technology and Innovation'. He shares some of this thought process behind novel nerve transfer or examination techniques, built on solid anatomical foundations and careful patient observations.

Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients.

The human genome project ushered in a genomic medicine era that was largely unimaginable three decades ago. Discoveries of druggable cancer drivers enabled biomarker-driven gene- and immune-targeted therapy and transformed cancer treatment. Minimizing treatment not expected to benefit, and toxicity-including financial and time-are important goals of modern oncology.

Literature review of occurrence, effectiveness, safety, and hospitalization burden of blood transfusion in the management of warm autoimmune hemolytic anemia.

Introduction: Cases of warm autoimmune hemolytic anemia (wAIHA) often present with life-threatening levels of hemoglobin requiring red blood cell (RBC) transfusion support.

Aim: This literature review assessed the occurrence, safety, effectiveness, and hospitalization burden of RBC transfusions in the management of patients with wAIHA.

Methods: Electronic databases (Embase, MEDLINE) were searched from inception to December 2021 along with additional searches conducted up to March 2024.

Assisted Reproductive Technologies in Latin America: the Latin American Registry, 2021.

Research Question: What are the trends and impact of new technologies on the effectiveness and safety of assisted reproductive technology (ART) performed in Latin America during 2021?

Design: This was a retrospective collection of cycle-based multinational data obtained from ART procedures performed by 204 accredited institutions in 16 countries.

Results: In total 127,351 initiated cycles resulted in 20,032 deliveries and 22,708 births. ART utilization showed great variability, from 623.

A nonsense variant in the C-terminal transactivation domain of the EBF3 gene in an individual with intellectual disability and behavioural disorder: case report and literature review.

Heterozygous variants in the Early B cell factor 3 (EBF3) have been reported in individuals presenting with hypotonia, ataxia and delayed development syndrome (HADDS) (MIM#617330). However, individuals with pathogenic variants in EBF3 show phenotypic heterogeneity and very few variants in the C-terminal domain have been described. We report on a heterozygous de-novo variant in the EBF3 gene in an individual with neurodevelopmental delay and behavioural problems.

Stable colonization of the model kissing bug Rhodnius prolixus by Trypanosoma cruzi Y strain.

Trypanosoma cruzi is a single-celled eukaryotic parasite responsible for Chagas disease, a major cause of morbidity and mortality in Central and South America. While the host-pathogen interactions of T. cruzi have been extensively studied in vertebrate models, investigations into its interactions within its insect host remain limited.

The territorialization of Severe Acute Respiratory Syndrome and its socioeconomic, demographic and public health policy risk factors in Belém, state of Pará, Eastern Amazon, Brazil: a cross-sectional and ecological study.

Severe Acute Respiratory Syndrome is an important public health problem in Brazil due to the large number of cases. It has a high mortality rate related to risk factors that include systemic arterial hypertension, type 2 diabetes mellitus, male gender and advanced age. This cross-sectional and ecological study analyzed the spatial distribution of this disease related to the evolution of COVID-19 cases and their epidemiological, demographic, socioeconomic and public health policy conditions in the administrative districts of Belém, state of Pará, in the eastern Brazilian Amazon, from 2021 to 2023.

Salacia crassifolia (Celastraceae) as a host of armored scale insects (Hemiptera: Diaspididae): two new reports and expansion of occurrence in Brazil.

Salacia crassifolia (Mart. Ex Schult.) G.

The marine and estuarine bony fishes (Teleostei) of the Golfão Maranhense on the eastern Amazon coast, northern Brazil.

The Golfão Maranhense is an extensive estuarine complex that provides nursery grounds and other habitats for several fish species, as well as a wealth of resources for the coastal and estuarine artisanal fisheries of the Maranhão state, in northern Brazil. The present study provides a comprehensive inventory of marine and estuarine teleost fishes of the Golfão Maranhense based on field samplings, analyses of voucher specimens from local collections and literature data. This inventory presents a total of 163 species of teleosts belonging to 107 genera, 57 families and 27 orders.

Lepidoptera (Insecta) of medical relevance of the state of Rio de Janeiro, Brazil.

Fourteen families of Lepidoptera are considered of medical relevance, with six of them recorded in Brazil. However, basic information on medically relevant Lepidoptera in Brazil is limited, with most studies focused on the southern region. This study presents the first comprehensive list of Lepidoptera of medical relevance for the state of Rio de Janeiro based on data from literature, iNaturalist, and the Taxonomic Catalog of the Brazilian Fauna.

Criteria for Research Productivity Grants in Brazil Applied to Civil Engineering: Reflections on Gender Differences and the Current Context.

This article addresses gender issues in the context of the professor's productivity grants (PQ) distribution applied to Civil Engineering. It contributes with reflections on the advancement of knowledge and gender equality through the inclusion of integrity and holistic aspects. A quantitative and descriptive data analysis of public documents revealed that the number of women civil engineers is considerable, and that female professors engaged in postgraduate are capable of competing for scholarships.

Teaching-learning strategies on patient safety in higher education institutions: a scoping review.

Objectives: to map the scientific production on teaching-learning strategies related to patient safety in higher education institutions across Nursing, Pharmacy, Medicine, and Dentistry programs.

Methods: this scoping review follows the Joanna Briggs Institute (JBI) guidelines and the PRISMA Extension for Scoping Reviews recommendations. The selection of studies was performed using databases, grey literature, and reverse searching, conducted by two independent and blinded reviewers.

The impact on body image and quality of life in breast cancer patients.

Objectives: to evaluate the quality of life and body image in women with breast cancer during chemotherapy, before and after interventions targeting body image.

Methods: we conducted a prospective cohort study with 47 women, utilizing both qualitative and quantitative data analysis.

Results: in the semi-structured interviews, 52.

Construction of a middle-range nursing theory for transpersonal home care.

Objectives: to describe the development of a middle-range nursing theory for transpersonal home care.

Methods: this is a theoretical study that used concept analysis, statement synthesis and derivation. It combined theoretical deduction strategies with induction, based on literature review and concept analysis.

Breastfeeding counseling in rooming-in care: a scoping review.

Objectives: to map evidence available in the literature on breastfeeding counseling in rooming-in.

Methods: a scoping review, following the stages recommended by the JBI to answer the review question: what evidence is available in the literature on breastfeeding counseling during the binomial's hospitalization in rooming-in? Searches were conducted in the PubMed/MEDLINE, LILACS, Scopus, EMBASE, Web of Science, CINAHL, PsycInfo and CAPES Dissertation and Theses Catalogue databases, using the descriptors "Counseling", "Breast Feeding", "Rooming-in Care" and "Mother-Child Binomial" and their synonyms, without time or language limitations.

Results: seven studies, published between 1999 and 2020, predominantly in English, were included in the analysis.

Construction and assessment of the quality of a care protocol for insulin use in hospitalized children and adolescents.

Objectives: to develop and assess the quality of a care protocol for safe insulin use in hospitalized children and adolescents.

Methods: a methodological study developed in three stages: scoping review, protocol development, and quality assessment. The scoping review followed the JBI recommendations, using the PRISMA-ScR checklist.

Thirst in critical patients and its associated factors.

Objectives: to assess prevalence, intensity, discomfort, defining characteristics of thirst and signs of oral mucosa hydration in Intensive Care Unit patients.

Methods: quantitative and analytical study, carried out in a tertiary hospital in six of the seven Intensive Care Units, with a sample of 60 patients. Variables related to thirst were analyzed according to their nature.

Mobile application for first aid to children: a technological innovation in schools.

Objectives: to develop a mobile application for first aid to children, designed for use by basic education professionals.

Methods: we carried out this applied research in three phases: 1-integrative review, 2- identification of learning needs through a cross-sectional study with 53 school professionals, and 3- app development.

Results: the Child and Care (Criança e Cuidado) app includes three main sections (Important contacts, Learn first aid, and Record the accident).

Undergraduate students' mental health in the first year of the COVID-19 pandemic: a scoping review.

Objectives: to map evidence on undergraduate students' mental health globally during the COVID-19 pandemic.

Methods: a scoping review, in which PRISMA-ScR was used.

Results: twenty-six articles were included, from which data were collected on the characteristics of articles, participants involved, and results.

Nurse participation in detecting signs of childhood autism in Primary Health Care.

Objectives: to understand nurse participation in the process of early detection of warning signs of autism spectrum disorders (ASD) in childcare consultations.

Methods: qualitative, exploratory research, conducted through semi-structured interviews conducted between August and November 2022 with 27 nurses from family clinics in the city of Rio de Janeiro. The IRaMuTeQ® software was used for data treatment.

Nurse's life world in organ donation and tissue.

Objectives: to understand the experience of nurses immersed in the everyday world of organ and tissue donation.

Methods: study on the social phenomenology of Alfred Schütz, carried out with 27 nurses who work on Intra-Hospital Committees for Donation of Organs and Tissues for Transplants in states in the Northeast of Brazil. Data were collected through phenomenological interviews and analyzed according to the adopted framework and compared with scientific productions.

Implementation of a high complexity nursing service in pediatric oncology.

Objective: to analyze how the process of implementing an onco-hematology nursing service at a pediatric hospital in Rio de Janeiro took place.

Methods: a historical, qualitative study. Sources included written and oral documents, produced through semi-structured interviews, carried out between August 2022 and February 2023 with nurses who worked on implementing the service, represented by 40 minutes, nine care protocols and eight reports from the hospital's internal website.

Healthcare-Associated Infections Controller: Concept Development.

Objective: To develop the concept of a Healthcare-Associated Infections Controller.

Method: A qualitative methodological study, based on the Hybrid Model of Concept Development, conducted in three phases: Theoretical Phase (through a scoping review with a sample of 28 studies), Field Phase (online meeting with 30 professionals in the field), and Final Analytical Phase (data analysis and concept definition).

Results: The antecedents, attributes, and consequences identified in the theoretical phase were similar to those described by the professionals.