Neonatal Abandonment and Hydrocephalus in Antillean Manatees (): Is There a Causal Relationship?

Manatees are semi-social animals, with the mother-calf relationship being considered long-lasting for the species. However, some events lead to the separation of this pair. Orphaned manatee calves can be adopted by other females of the same species.

Reproduction and Development in Fish: Solving Bottlenecks in Modern Aquaculture.

The aquaculture industry is home to the fastest-growing activity in the agriculture sector worldwide and is one of the leading sectors in global food production [...

Short Supply of High Levels of Guanidine Acetic Acid, Alters Ovarian Artery Flow and Improves Intraovarian Blood Perfusion Area Associated with Follicular Growth in Sheep.

Guanidinoacetic acid (GAA), a precursor of creatine, has a recognized effect on ruminant performance when used as a dietary supplement. However, its impact on reproductive response remains to be elucidated. Therefore, this study aimed to contribute initially to this area by supplementing the diets of ewes with a high dose of GAA, evaluating its effects on reproductive response.

Phenotypic Presentation of Children with Joint Hypermobility: Preclinical Signs.

Introduction: Joint hypermobility (JH) is mobility beyond the normal range of motion. JH can be an isolated finding or a characteristic of a syndrome. Characteristics related to the sitting position with atypical body positions, such as sitting in splits (S), with the foot on the head (F), in W (W), in a concave shape (C), episodes of dislocations, and subluxations, suggest impacts on body mechanics since childhood, with damage to the conformation of the joints.

Effects of Exergaming on Morphological Variables, Biochemical Parameters, and Blood Pressure in Children and Adolescents with Overweight/Obesity: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.

Objectives: This systematic review with meta-analysis aimed to evaluate the available body of published peer-reviewed studies on the effects of exergaming (EXG) compared to the control group (CG) on morphological variables, biochemical parameters, and blood pressure in children and adolescents with overweight/obesity.

Methods: A systematic literature search was conducted until September 2024 using five databases: PubMed, Medline, CINAHL Complete, Scopus, and Web of Science. PRISMA, TESTEX, RoB 2, and GRADE tools assessed the methodological quality and certainty of evidence.

The Influence of Socio-Affective Relationships Between Adolescents in Educational Experiences of Cooperation-Opposition: A Systematic Review.

Background/objectives: Socio-affective relationships have garnered increasing attention in recent years as a means to enhance coexistence and well-being. Within this context, educational institutions play a pivotal role in shaping peaceful coexistence and promoting well-being among future generations. Physical Education (PE) is particularly significant, because it integrates cooperative-opposition activities, which blend collaboration and competition, fostering socio-emotional development.

NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue.

: Aging is associated with structural and functional changes in the heart, including hypertrophy, fibrosis, and impaired contractility. Cellular mechanisms such as senescence, telomere shortening, and DNA damage contribute to these processes. Nuclear factor kappa B (NF-κB) has been implicated in mediating cellular responses in aging tissues, and increased NF-κB expression has been observed in the hearts of aging rodents.

Advancing Hydrogel-Based 3D Cell Culture Systems: Histological Image Analysis and AI-Driven Filament Characterization.

Machine learning is used to analyze images by training algorithms on data to recognize patterns and identify objects, with applications in various fields, such as medicine, security, and automation. Meanwhile, histological cross-sections, whether longitudinal or transverse, expose layers of tissues or tissue mimetics, which provide crucial information for microscopic analysis. : This study aimed to employ the Google platform "Teachable Machine" to apply artificial intelligence (AI) in the interpretation of histological cross-section images of hydrogel filaments.

Structural Disruption of Cilia and Increased Cytoplasmic Tubulin in Biliary Atresia-An Exploratory Study Focusing on Early Postoperative Prognosis Following Portoenterostomy.

Biliary atresia (BA) is a progressive hepatobiliary disease in infants, leading to liver failure and the need for transplantation. While its etiopathogenesis remains unclear, recent studies suggest primary cilia (PC) disruption plays a role. This study investigates correlations between PC and cytoplasmic tubulin (TUBA4A) alterations with hypoxia in patients with the isolated form of BA, focusing on native liver survival.

Rescue of Mutant CFTR Channel Activity by Investigational Co-Potentiator Therapy.

The potentiator VX-770 (ivacaftor) has been approved as a monotherapy for over 95 cystic fibrosis (CF)-causing variants associated with gating/conductance defects of the CF transmembrane conductance regulator (CFTR) channel. However, despite its therapeutic success, VX-770 only partially restores CFTR activity for many of these variants, indicating they may benefit from the combination of potentiators exhibiting distinct mechanisms of action (i.e.

Emerging Trends in Non-Invasive Brain Stimulation: The New Kids on the Block.

In the Sustainable Development Goals of the United Nations for 2030, mental health has been identified as a global priority, emphasizing the need to reduce the prevalence, morbidity, and premature mortality associated with mental disorders [...

Analysis of the Climate Impact on Occupational Health and Safety Using Heat Stress Indexes.

Unlabelled: Workers may be exposed to conditions that put their physical and mental integrity at risk, from workplace settings to climate characteristics. Heat stress is a harmful health condition caused by exceeding the human body's tolerance limits, leading to illness and increasing the chance of work accidents. Heat stress indexes, such as the Humidex and the Heat Index (HI), are used to measure these impacts.

Incidence of Tooth Loss in Remote Indigenous Populations of the Amazon Region: A 13-Year Cohort Study Before and After Belo Monte Dam.

Tooth loss among indigenous people in the Amazon emphasizes the need for culturally appropriate oral health interventions. The objective of this study was to analyze the incidence of tooth loss in two remote Amazon indigenous populations. This prospective cohort evaluated a total of 47 indigenous in the permanent dentition at T0 and thirteen years later (T1) from two villages, Arara-Laranjal (n = 28, mean age 16.

Enhancing Post-Training Muscle Recovery and Strength in Paralympic Powerlifting Athletes with Cold-Water Immersion, a Cross-Sectional Study.

(1) Background: The recovery method is important and decisive in the training system. This study aimed to assess the effects of various post-training recovery methods on muscle damage and strength indicators in Paralympic powerlifting athletes. (2) Methods: A crossover study was conducted involving eleven male athletes (25.

The First Report of Environmental Exposure to Barium in 10 Localities Close to Industrial Areas and Ports in the Amazon.

Environmental exposure to metallic contaminants such as barium (Ba) is a worldwide concern, as these metals can even be toxic to the human body. Data on different sources of exposure to Ba and possible routes of entry are important for preventing adverse health effects. Blood Ba levels were evaluated in 10 localities in the cities of Barcarena and Abaetetuba in the Amazon.

WHOQOL-BREF in Measuring Quality of Life Among Sickle Cell Disease Patients with Leg Ulcers.

Sickle cell disease (SCD) presents complex clinical manifestations influenced by genetic, social, environmental, and healthcare access factors as well as socioeconomic status. In this context, sickle cell leg ulcers (SLUs) are a debilitating complication of SCD. We aimed to describe sociodemographic data and evaluate the quality of life (QoL) of SCD patients with and without SLUs.

Comparison Between Water Aerobics and Deep-Water Running on Middle-Aged Adults' Anthropometric, Hemodynamic and Functional Outcomes.

Background: Head-out aquatic training, using modalities such as water-aerobics/hydrogymnastics (HYD) and deep-water running (DWR), has been effective in improving the physical, metabolic and cognitive health of middle-aged adults. However, direct comparisons between these modalities are lacking.

Aim: The aim of this study was to compare the effects of water aerobics and deep-water running on anthropometric, functional and hemodynamic outcomes in adults and older adults.

Effects of an Easily Implemented Physical Exercise Program on the Ventricular Ejection Fraction of Women with Breast Cancer Undergoing Chemotherapy.

Breast cancer (BC) is the most common cancer among women, with an incidence of 85-94 per 100,000 people annually in Europe. Despite the increasing incidence of BC, advancements in early detection and novel therapeutic approaches have improved survival rates. However, adjuvant treatments are associated with side effects, including a reduction in the left ventricular ejection fraction (LVEF), which can result in severe cardiac damage and progress to heart failure.

The Brazilian Portuguese Version of the Behavioral Regulation in Exercise Questionnaire 3 (BREQ-3) Is Reliable and Valid for Assessing Motivational Regulations and Self-Determination in Exercise Among Adults Aged 50 Years or Older: A Methodological Study.

The study aimed to investigate the reliability, construct, and discriminant validity of the Behavioral Regulation in Exercise Questionnaire 3 (BREQ-3) for evaluating motivational regulations and self-determination for exercise in Brazilian adults aged 50 years or older. The study assessed motivation for exercise, peripheral muscle strength, physical performance, functional capacity, cardiovascular fitness, and frailty phenotype. Two raters independently applied the BREQ-3.

Comparative Electrocardiographic Analysis Between Physical Exercise Practitioners and Athletes: A Cross-Sectional Study.

The trained heart adapts through geometric changes influenced by concentric and eccentric hypertrophy, depending on the predominance of the isometric or dynamic components of the exercise performed. Additionally, alterations in heart rhythm may occur due to increased vagal system activity. Cardiological evaluation with an electrocardiogram (ECG) aims to identify cardiac conditions that could temporarily or permanently disqualify an athlete from competition.

Quality of Oral Anticoagulation Control with Warfarin According to Sex: A Cross-Sectional Study.

Evidence indicates a difference between men and women in oral anticoagulation control, but the results were discrepant. This study investigated the association of sex with oral anticoagulation control in patients on warfarin assisted by anticoagulation clinics (ACs) in Brazil. The cross-sectional study included patients on warfarin recruited at three public ACs in southeast Brazil (2014-2015).

The Influence of Mat Pilates Training on Cardiometabolic Risk Factors in Postmenopausal Women with Single or Multiple Cardiometabolic Diseases.

This study compared the effects of Mat Pilates training on cardiovascular risk markers in postmenopausal women with single or multiple cardiometabolic conditions. Forty-four women were divided into single-condition (SINGLE; = 20) and multiple-condition (MULTI; = 24) groups. Both groups completed Mat Pilates three times per week for 12 weeks.

Impact of Respiratory Support During Hospitalization on Functional Outcomes in Long COVID: A Post-Hoc Analysis of a Prospective Cohort Study.

Post-acute COVID-19 syndrome (PACS) is characterized by the persistence of one or more symptoms after the acute phase, leading to physical disabilities. This study aims to investigate whether the functional capacity and respiratory function 120 days post-COVID-19 differed according to the level of respiratory support needed during hospitalization in acute COVID-19 in the pre-vaccine rollout period. We followed up with 118 COVID-19 hospitalized patients in the acute phase until 120 days post-acute disease, with patients split into a Non-Invasive Oxygen Therapy Group (OTG, n = 72), Invasive Mechanical Ventilation Group (IMV, n = 12), and Room Air Group (RAG, n = 34), assessing the body composition, respiratory muscle strength, pulmonary function, functional capacity, and muscle strength at the follow-up visit.

A Single Session of Beach Tennis with Recreational Athletes Improves Anxiety Symptoms in Women but Not in Men: A Randomized Trial.

Introduction: Beach tennis has become a popular sport, but research on its mental health benefits is scarce. To the best of our knowledge, no studies have examined the effects of beach tennis on anxiety symptoms.

Objectives: To assess the effect of a single session of beach tennis, in both singles and doubles modes, on anxiety symptoms.

Psychosocial Impact of the COVID-19 Pandemic in Brazilian Post-Peak Period: Differences Between Individuals with and Without Pre-Existing Psychiatric Conditions.

(1) Background: Validated instruments to measure mental health variables related to sanitary crises can provide data for prevention or intervention plans. The objectives of this study were: (1) to evidence the psychometric factorial internal structure of the Battery for Assessing Mental Health-Pandemic Version (BASM-P) in the sample; (2) to investigate the psychosocial impact of the COVID-19 pandemic in Brazilian post-peak period among individuals with and without pre-existing psychiatric conditions using the BASM-P; and (3) to analyze relationships between the mental health variables measured by the BASM-P in both groups. (2) Methods: This is an internet-based quantitative, cross-sectional study with a non-probabilistic convenience sample.