Is There Scientific Evidence on the Practice of Rib Resection or Remodeling for Body Contouring Purposes?-A Systematic Review.

Introduction: Rib resection and remodeling have gained attention as cosmetic procedures to enhance body contours, particularly waist-to-hip ratio. Historically, rib resection has been used for medical reasons; however, plastic surgeons have recently adopted it for aesthetic purposes. However, concerns remain regarding the safety and effectiveness of the procedure, particularly due to the potential for complications, such as pneumothorax, chronic pain, and impaired respiratory function.

Carbon nanotubes stabilized in chitosan sponge (CNT-CS) as a new alternative clean-up sorbent for pesticide multiresidue determination in eggplants using QuEChERS and UHPLC-MS/MS.

The continuous development and application of pesticides in agriculture require robust multiresidue detection methods to guarantee food safety. This study introduces a novel method for multiresidue determination of pesticides in eggplants using the QuEChERS procedure, incorporating a clean-up step using carbon nanotubes stabilized in chitosan sponge (CNT-CS) and ultra-high performance liquid chromatography with tandem mass spectrometry (UHPLC-MS/MS) for analysis. Upon identifying the optimal extraction conditions, various sorbents were assessed for their efficacy in the dispersive solid-phase extraction (d-SPE).

The association of origin and environmental conditions with performance in professional IRONMAN triathletes.

We have (i) little knowledge about where the fastest professional IRONMAN triathletes originate from and where the fastest races take place and (ii) we have no knowledge of the optimal weather conditions for an IRONMAN triathlon. The aims of the present study were, therefore, (i) to investigate the origin and the fastest IRONMAN race courses for professional triathletes and (ii) to evaluate the best environmental conditions (i.e.

Reproductive effects of the insecticide acephate on a springtail and an enchytraeid in a subtropical soil.

The widespread use of acephate, a common insecticide, raises concerns about its potential impacts on nontarget soil organisms. This study investigated the chronic effects of acephate on the reproduction of two key soil fauna species, the springtail Folsomia candida and the enchytraeid Enchytraeus crypticus. We exposed these organisms to acephate in both natural Cambisol soil and tropical artificial soil (TAS) to assess potential impacts under different environmental conditions.

Improving full-arch implant scanning accuracy with a Meccano-like device for scan bodies splinting: A dental technique.

A long-term successful implant-supported prosthesis requires the creation of a passively fitting framework, based on an accurate intraoral digital implant scan. According to dental literature, splinted implant scan bodies (ISBs) provide higher intraoral scanning accuracy than non-splinted techniques. This technique presents a structured approach for splinting multi-unit abutment scan bodies (MUASBs) using customized manufactured devices to facilitate the recording of definitive intraoral implant scans.

Sodium Thiosulfate Treatment for Calciphylaxis: Is There an Optimal Duration of Therapy?

Calciphylaxis is a rare and serious disorder characterized by vascular calcification and occlusion of the microvessels in the dermis, subcutaneous adipose tissue, visceral organs, and musculature. Studies have suggested that the major risk factors for developing calciphylaxis are chronic kidney disease and secondary hyperparathyroidism. Its diagnosis is clinical, and the treatment includes a multidisciplinary approach, although there are no clinical protocols based on randomized clinical trials.

Trends in Specific Family Refusals for Pediatric Organ and Tissue Donation: A Cross-Sectional Study.

Background: When a family decides to donate the organs or tissues of their child with brain death, it is necessary to consider which organs or tissues will be donated. This phenomenon presents an ethical dilemma that is underexplored in the scientific literature, making it essential to examine this context to understand how refusals occur within donations.

Objective: To analyze the rates and trends of specific refusals for each organ and tissue from pediatric donors with brain death occurring between 2001 and 2020 in an Organ Procurement Organization in the State of São Paulo, Brazil.

The Renal Effect of 20% Human Albumin Solution Fluid Bolus Therapy in Patients After Cardiac Surgery. A Secondary Analysis of the HAS FLAIR II Randomized Clinical Trial.

Objective: To compare the effects of fluid bolus therapy (FBT) with 20% albumin to crystalloid FBT on the incidence of cardiac surgery-associated acute kidney injury (CSA-AKI) and its severity and duration.

Design: Secondary analysis of the multicenter, parallel-group, open-label, randomized HAS FLAIR-II trial.

Setting: Six intensive care units.

Outcomes of Intrauterine Interventions in Twin Reversed Arterial Perfusion (TRAP) Sequence: A Systematic Review of the Literature Over the Past 35 Years.

Twin reversed arterial perfusion (TRAP) sequence is an uncommon disease affecting monochorionic twin pregnancies. The diagnosis can be made by ultrasound allowing to plan optimal antenatal management. An electronic search was conducted from inception to July 2024 to systematically evaluate and compare the outcomes of different intrauterine interventions in this condition.

Association of muscle strength and cardiorespiratory fitness with all-cause and cancer-specific mortality in patients diagnosed with cancer: a systematic review with meta-analysis.

Objectives: To examine the association between muscle strength and cardiorespiratory fitness (CRF) with all-cause and cancer-specific mortality in patients diagnosed with cancer, and whether these associations are affected by type and/or stage of cancer.

Method: A systematic review with meta-analysis was carried out. Five bibliographic databases were searched to August 2023.

Covert variations of a musician's loudness during collective improvisation capture other musicians' attention and impact their interactions.

While research on auditory attention in complex acoustical environment is a thriving field, experimental studies thus far have typically treated participants as passive listeners. The present study-which combined real-time covert loudness manipulations and online probe detection-investigates for the first time to our knowledge, the effects of acoustic salience on auditory attention during live interactions, using musical improvisation as an experimental paradigm. We found that musicians were more likely to pay attention to a given co-performer when this performer was made sounding louder or softer; that such salient effect was not owing to the local variations introduced by our manipulations but rather likely to be driven by the more long-term context; and that improvisers tended to be more strongly and more stably coupled when a musician was made more salient.

Continuous colonization of the Atlantic coastal rain forests of South America from Amazônia.

The two main extensions of rain forest in South America are the Amazon (Amazônia) and the Atlantic rain forest (Mata Atlântica), which are separated by a wide 'dry diagonal' of seasonal vegetation. We used the species-rich tree genus to test if Amazônia-Mata Atlântica dispersals have been clustered during specific time periods corresponding to past, humid climates. We performed hybrid capture DNA sequencing of 810 nuclear loci for 453 accessions representing 164 species that included 62% of Mata Atlântica species and estimated a dated phylogeny for all accessions using maximum likelihood, and a species-level tree using coalescent methods.

Excipients in drug delivery systems: A comprehensive review of approved inactive ingredients for human ophthalmic formulations.

Pharmaceutical excipients, commonly known as inactive ingredients, encompass any substance aside from the active ingredient that fulfills a distinct and vital role in a formulation. Their purpose is to enhance specific characteristics, whether associated with the performance of the formulation or aspects related to patient comfort, safety, and acceptability. Because of the limited toxicity studies provided, and the several allergic and toxic side effects that have been reported throughout the years, it is not trivial for the regulatory agencies to approve inactive ingredients for human use.

Antileishmanial activity of Hesperetin on Leishmania donovani, in vitro and in silico inhibition of acetylcholinesterase and investigation of the targets sterol C-24 reductase and N-myristoyltransferase.

The current treatment of leishmaniasis is confronted with significant challenges, including limited efficacy, adverse effects, and parasite resistance to drugs. The search for alternative therapeutic options, including the utilization of natural products, has demonstrated considerable promise. In this study, the antileishmanial activity of the flavonoid hesperetin against Leishmania donovani, the causative agent of visceral leishmaniasis, was reported for the first time.

Intranasal liposomal remdesivir induces SARS-CoV-2 clearance in K18-hACE2 mice and ensures survival.

A huge challenge after the emergence of COVID-19 has been the discovery of effective antiviral drugs. Although remdesivir (RDV) emerged as one of the most promising drugs, its pharmaceutical formulation Veklury® is limited by moderate efficacy, high toxicity and need for parenteral administration. The aim of the present work was to develop a liposomal formulation of RDV for pulmonary administration and evaluate its efficacy in models of COVID-19.

Tailoring a lignocellulosic biomass to simultaneously enhance N-doping and textural properties of porous carbons designed for effective environmental remediation.

Transforming lignocellulosic biomass waste into value-added materials like porous carbons offers a sustainable and increasingly important solution for its efficient management within a circular economy framework. Although the heteroatom-doping process enhances oxygen- or nitrogen-containing functionalities on porous carbons, it often leads to losses in structural integrity and other key functionalities. This study presents a novel protocol to produce N-doped porous carbons that efficiently introduces nitrogen groups while improving surface area, microporosity definition and the concentration of oxygen-containing functionalities.

Analysis of the biomolecular profile by Fourier transform vibrational spectroscopy (FT-IR) in Acinetobacter baumannii after application of photodynamic therapy with curcumin "in vitro ".

Acinetobacter baumannii stands out for its antimicrobial resistance and high capacity to cause hospital infections, posing a severe threat to global public health. Thus, there is an urgent need for new therapeutic strategies. This work applied photodynamic therapy (PDT) with curcumin to Acinetobacter baumannii, and bacterial cell viability was assessed.

Growth-tolerance tradeoffs shape the survival outcomes and ecophysiological strategies of Atlantic Forest species in the rehabilitation of mining-impacted sites.

The initial performance of seedlings of tree species from different functional groups, regarding the growth-defense tradeoff, might determine its long-term success during the rehabilitation of mining areas. We monitored the field performance of six native tree species of the Atlantic Forest in the Fundão dam tailing that has been under rehabilitation for 35 months. Additionally, we explored the morphophysiological traits driving the superior performance of three species.

Thermal stresses in porcelain veneered lithium disilicate and zirconia dental crowns: Comparative analysis using a validated viscoelastic finite element model.

This study aims to investigate the effects of material compatibility, variable cooling rates, and crown geometry on thermal stress development in porcelain-veneered lithium disilicate (PVLD) and porcelain-veneered zirconia (PVZ) dental crown systems, and subsequently anticipate parameters for their optimum performance. An anatomically correct 3D crown model was developed from STL files generated using 3D scans of the experimental crown sample. Next, the viscoelastic finite element model (VFEM) based on the 3D crown model was developed and validated for anatomically correct bilayer PVLD and PVZ crown systems.

Ultrasonic characterization of 3D-printed polymer objects.

3D printing technology, also known as Additive Manufacturing (AM), has revolutionized object prototyping, offering a simple, cost-effective, and efficient approach to creating structures with diverse spatial features. However, the mechanical properties of 3D-printed structures are highly dependent on the material type and manufacturing technique employed. In this study, ultrasonic testing methods were used to comprehensively characterize standard samples produced using two popular printing techniques: material extrusion and vat photopolymerization.

Motor dysfunction in preschool children exposed to zika virus during pregnancy and normocephalic at birth: Developmental Coordination Disorder and Minimal Neurological Dysfunction.

The occurrence of motor dysfunctions was assessed at the age of 5 to 7 years in 61 normocephalic infants with prenatal Zika virus exposure. Traditional neurological examination, Touwen neurological examination, Movement Assessment Battery for Children-Second Edition (MABC-2) and the Developmental Coordination Disorder Questionnaire (DCDQ) were used to identify Developmental Coordination Disorder (DCD) and Minimal Neurological Dysfunction (MND). A high frequency of motor dysfunctions was found, 47 (81.

Computational simulation of graphene/h-BN nanopores for single-molecule herbicide sensing.

The growing world population and climate change are key drivers for the increasing pursuit of more efficient and environmentally-safe food production. In this scenario, the large scale use of herbicides demands the development new technologies to control and monitor the application of these compounds, due to their several environmental and health-related problems. Motivated by all these issues, in this work, a hybrid graphene/boron nitride nanopore is explore to detect/identify herbicide molecules (Glyphosate, AMPA, Diuron, and 2,4-D).