Specific immunohistochemical expression of Mmp-26 in prostatic adenocarcinoma.

Matrix metalloproteinases (MMP) have been identified as biomarkers for several diseases, including cancer. The increase in the expression of these enzymes has been related to greater tumor aggressiveness. MMP-26 is expressed constitutively in the endometrium and some cancer cells of epithelial origin.

The Southern Brazilian Registry of Atrial Fibrillation (SBR-AF Registry): Predictors of Atrial Arrhythmia Recurrence after First-Time Catheter Ablation.

Background: Treatment of atrial fibrillation (AF) with catheter ablation (CA) has evolved significantly. However, real-world data on long-term outcomes are limited, particularly in low- and middle-income countries.

Objective: This multicenter prospective cohort of consecutive patients aimed to evaluate the safety and efficacy of first-time CA for AF in Southern Brazil from 2009 to 2024.

IMPACT OF COVID-19 PANDEMIC ON THE SURGICAL TREATMENT OF GASTRIC CANCER: A 3-YEAR ANALYSIS.

Background: The COVID-19 pandemic has overloaded healthcare systems worldwide. Other diseases, such as neoplasms, including gastric cancer, remained prevalent and had their treatment compromised.

Aims: The aim of this study was to evaluate the impact of the COVID-19 pandemic on the treatment of gastric cancer and adherence to the recommended preoperative COVID-19 screening protocol.

MELANOMAS, SARCOMAS, AND RENAL METASTASES IN THE LIVER: HOW TO TREAT?

Liver metastases from melanomas, sarcomas, and renal tumors are less frequent. Treatment and prognosis will depend on whether they are isolated or multiple, size and location, the presence or absence of extrahepatic neoplastic disease, age, stage of the initial disease, initial treatments instituted, time of evolution, and clinical condition of the patient. Recently, a high number of oncological therapies including monotherapy or in combination, neoadjuvants or adjuvants, and immuno-oncological treatments have been developed and tested, increasing disease-free time and survival.

CARDIOVASCULAR RISK BEFORE AND AFTER SURGICAL TREATMENT OF SEVERE OBESITY.

Background: Obesity is a predisposing factor for serious comorbidities, particularly those related to elevated cardiovascular mortality. The atherogenic index of plasma (AIP) has been shown to be a useful indicator of patients with insulin resistance.

Aims: The aim of this study was to assess cardiovascular risk before and after surgical treatment of obesity.

Analyzing the effectivity of evidence-based practice in health science higher education: a narrative review.

Background: Although multiple strategies have been suggested for evidence-based practice educational interventions, few studies have focused on the development of abilities for evidence-based practice implementation.

Objective: To explore the effectiveness of evidence-based practice in higher education and understand its teaching methods.

Design And Setting: Narrative review was conducted at the Universidade Municipal de São Caetano do Sul, Brazil.

Play Nicely Program in the prevention of violence against children: strengthening sustainable development.

Objective: to understand the perception of teachers and health professionals regarding the use of the Play Nicely Program for parents/caregivers in the prevention of violence against children.

Method: a descriptive and exploratory qualitative study was conducted through three focus groups with twenty primary school teachers and primary health care professionals who implemented the Program for parents/caregivers in 2022. The data analysis was guided by French discourse analysis, interpreted through the lens of Urie Bronfenbrenner's theory.

Coordination of care in health systems for users with diabetes and hypertension: a scoping review.

Objective: to map the available evidence on the characteristics of care coordination between Primary Health Care and Specialized Outpatient Care for users with diabetes and hypertension.

Method: this is a scoping review with 40 articles as the final sample, evaluated by means of Content Analysis, of the thematic-categorical type, with the aid of a technological tool.

Results: care coordination was defined by means of eight categories: information and communication, integration of care, improvement and quality, care management, care sharing, fundamental attribute, health professionals and health service users, with the results of the articles concentrating mainly on four categories, with information and communication standing out, followed by the category of care management and the category of care sharing, in parallel with improvement and quality.

Demonstration of sizing nursing staff methods in intensive care.

Objective: to demonstrate the sizing of intensive care nursing staff estimated by two calculations, using the Nursing Activities Score as one of its central components.

Method: descriptive, retrospective study that compiled the Nursing Activities Score scores of patients in five Intensive Care Units of a hospital in southern Brazil. Two calculations were used to size the nursing staff.

Ambient temperature and hospitalizations of children due to respiratory diseases in Cuiabá-MT, Brazil.

This study evaluated the role of temperature and fine particulate matter in hospitalizations of children living in Cuiabá-MT, obtained from DATASUS, between 01/01/2016 and 12/31/2018. Daily concentrations of the pollutant fine particulate matter were estimated using the CAMS mathematical model, made available by CPTEC. Diagnoses of tracheitis and laryngitis, pneumonia, bronchitis, bronchiolitis and asthma were included.

Factors associated with the notification of violence among Brazilian adolescents: an analysis of SINAN.

This study aims to analyze the trend of the notified violence committed against adolescents from 2015 to 2022 and the association between the victim's characteristics, abuse, and the perpetrators of violence against adolescents in 2022. It used data from the Notifiable Diseases Information System (SINAN). Around 400,000 cases of violence against adolescents were reported.

"Water" Populations: Environment-Health, from the Social Determination and Health Policy perspective, in the Baixo Amazonas Region-PA.

The relationship between the environment and health has become a relevant topic on the public policy agenda since the 1990s. This study seeks to describe this relationship from the perspective of the National Policy for Comprehensive Health of Populations of the Countryside, Forest, and Waters in the community of São Pedro, in the Lower Amazon region of Pará. This is a descriptive study focused on conducting diagnoses that consider the environment-health relationship in the Community.

Timely initiation of antenatal care in adolescent victims of sexual violence: implications for legal abortion in Brazil.

We investigated the timely initiation of antenatal care among Brazilian adolescents to support the national discussion on the gestational age limit for legal abortion. Using data from the Live Births Information System (SINASC) 2020-2022, we correlated the timely antenatal care (first quarter of pregnancy) with the adolescent's age, region, ethnicity/skin color, and schooling level; 11,607 annual births result from vulnerable rape. The timely initiation of antenatal care was 70.

Do Brazilian Olympic athletes live longer than the general population? A retrospective cohort study.

We investigated if Brazilian Olympic athletes live longer than the general population, and if there are differences between the types of sport. This is a retrospective cohort study with secondary data analysis. Data from Brazilian athletes of both sexes were included, from the 7th edition (1920) to the 25th edition (1992) of the Modern Olympic Games.

Costs and characteristics of admissions due to ambulatory care-sensitive conditions in children under one year of age in São Paulo, Brazil.

This research aimed to estimate the direct costs and analyze the epidemiological aspects of ambulatory care-sensitive conditions (ACSC) in children under one year of age, São Paulo municipality, 2011-2022. Total and average costs were calculated according to ACSC diagnosis groups by components (early neonatal, late neonatal, and post-neonatal). The trend in ACSC rates was analyzed using Prais-Winsten generalized linear regression.

[Alcohol consumption and incidence of abdominal obesity in participants of the ELSA-Brasil cohort after nine years of follow-up].

The scope of this article is to analyze the correlation between alcohol consumption and abdominal obesity in participants of the ELSA-Brasil cohort after a follow-up period of nine years. A longitudinal analysis was performed with baseline and follow-up data from ELSA-Brasil. At baseline, 15,105 civil servants were enrolled.

Social health determinants associated with mammography performance according to the 2013 and 2019 National Health Survey.

Mammography is one of the main methods available for breast cancer screening in Brazil. However, differences in timely access and performance of the exam can be highlighted based on social determinants of health, considered relevant due to their influence on the health situation of a population. Thus, the present study aimed to identify the social determinants of health associated with access to and performance of mammography in Brazilian women.

[Advances and challenges in the transsexualizing process in the Brazilian Unified Health System].

The implementation of the Transsexualizing Process (TP) / Gender-affirming Surgeries (GAS) in the Unified Health System (SUS) was the result of social struggles by the LGBT community for sexual rights, the construction of gender identity, and bodily autonomy. The scope of this article is to analyze the advances and challenges of TP/GAS in the SUS, through a qualitative narrative literature review. In June 2022, searches were conducted in the Google Scholar, SciELO, and VHL databases to select scientific articles in Portuguese published in the last 10 years, excluding articles in foreign languages and other types of academic work such as reviews, undergraduate theses, dissertations, and/or graduate theses.

Impact of the COVID-19 pandemic on the incidence of occupational accidents among beneficiaries of the Unified Health System in Brazil: an interrupted time series study.

The scope of this study was to analyze the impact of the COVID-19 pandemic on the incidence of occupational accidents among beneficiaries of the Unified Health System in Brazil. It was an interrupted time series study, using data on occupational accidents registered by the Unified Health System from 2015 to 2020. The analysis used the Prais-Winsten generalized linear regression model.