667 results match your criteria: "Brawijaya University.[Affiliation]"

Introduction: Knee joint stability is influenced by force distribution and ligament structures. High Tibial Osteotomy (HTO) treats knee deformities and redistributes load, reducing further invasive procedures. High Tibial Osteotomy (HTO) is a well-established procedure for addressing knee instability, particularly in cases involving ligament deficiencies such as ACL and PCL insufficiencies.

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Background: Rheumatic atrial fibrillation (AF) patients are at an elevated risk of stroke events, yet the associated risk factors remain unclear.

Objectives: This study aimed to evaluate the effectiveness of the CHADS-VASc score in predicting stroke events in rheumatic AF patients and explore potential enhancements for increased predicting accuracy in the Asian population, comparing it to nonvalvular AF.

Methods: A retrospective cohort study spanning March 2010 to December 2020 included 29,341 AF patients followed up for up to 10 years, with 1,942 identified as having rheumatic AF.

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Crash box development is carried out continuously to obtain a lightweight design and high energy absorption. This dataset presents the results of a crash box experiments. Quasi-static testing of aluminum, honeycomb, and hybrid tube specimens was carried out using a universal testing machine.

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Background: Percutaneous Endoscopic Lumbar Discectomy (PELD) is a leading minimally invasive technique for lumbar disc herniation (LDH). The two primary approaches, transforaminal (PETD) and interlaminar (PEID), each present distinct advantages and challenges in treating L5-S1 LDH. This study aims to compare the efficacy and safety of these two approaches.

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Characteristics of naturally woven Waru bark fiber for eco-friendly composite reinforcement.

Int J Biol Macromol

January 2025

Advanced Engineering Materials and Composite Research Centre (AEMC), Department of Mechanical and Manufacturing Engineering, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.

The aim of this study was to investigate the potential of Waru bark fiber (WBF) as a reinforcement material for composites. To achieve this aim, WBF was extracted using a conventional process, to ensure its purity, and then characterized for physical, mechanical, chemical, and thermal properties. Microstructure analysis was performed using Scanning Electron Microscope (SEM) to show uniform and exceptional fiber sheets with naturally woven fiber shapes.

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Data is becoming increasingly ubiquitous today, and data literacy has emerged an essential skill in the workplace. Therefore, it is necessary to equip high school students with data literacy skills in order to prepare them for further learning and future employment. In Indonesia, there is a growing shift towards integrating data literacy in the high school curriculum.

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Background: Stress can cause an increase in proinflammatory cytokines, IL-6, which plays a role in the inflammatory response and causes changes in the placenta, causing a low risk of the fetus being born. Giving nanocurcumin, which functions as an anti-inflammatory and antioxidant, is expected to reduce cortisol levels which increase during pregnancy.

Aim: This study aims to determine the effect of stress during pregnancy on pregnant mice, namely IL-6 expression and fetal body weight.

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Industrial organic dyes represent a significant portion of pollutants discharged into the environment, particularly by the textile industry. These compounds pose serious threats to living organisms due to their high toxicity. Various techniques have been explored for the degradation of organic dyes, among which heterogeneous photocatalysis utilising titanium dioxide (TiO) stands out as a promising technology.

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Enhancing mechanical and thermal properties of bio-composites: Synergistic integration of ZnO nanofillers and nanocrystalline cellulose into durian seed starch matrix.

Int J Biol Macromol

December 2024

Natural Composites Research Group Lab, Department of Materials and Production Engineering, The Sirindhorn International Thai-German Graduate School of Engineering (TGGS), King Mongkut's University of Technology North Bangkok (KMUTNB), Bangkok 10800, Thailand.

The increasing demand for sustainable materials necessitates advancements in bio-composites with enhanced properties. This study addresses the limitations of Durio zibethinus Murr (DZM) seed starch bio-composites, particularly their poor mechanical strength and thermal stability. Using solution casting, zinc oxide (ZnO) nanofillers and nanocrystalline cellulose (NCC) were incorporated into the starch matrix.

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The rich diversity of herbal plants in Indonesia holds immense potential as alternative resources for traditional healing and ethnobotanical practices. However, the dwindling recog-nition of herbal plants due to modernization poses a significant challenge in preserving this valuable heritage. The accurate identification of these plants is crucial for the continuity of traditional practices and the utilization of their nutritional benefits.

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Background: Digital servitization is a strategic transformation where companies adopt a service-focused approach in response to the prevailing trend of digitalization. Utilizing digital technology, businesses manage product and service operations and develop new value propositions. Further research into digital servitization is essential for maintaining competitiveness and meeting evolving market demands globally.

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Article Synopsis
  • OPN is expressed in osteoblasts and its levels increase during their differentiation, with two isoforms: secretory (sOPN) and intracellular (iOPN).
  • Overexpression of wild type OPN (which includes both isoforms) enhances matrix mineralization and osteogenic markers, while overexpression of iOPN specifically inhibits these processes.
  • The secretion of OPN is positively regulated by JNK activity in osteoblasts, highlighting distinct roles for each isoform in osteoblast differentiation.
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Theoretical investigation of selective inhibitory activity of chromone-based compounds against monoamine oxidase (MAO)-A and -B.

J Biomol Struct Dyn

December 2024

Drug Discovery and Synthetic Chemistry Research Group, Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia.

Article Synopsis
  • Monoamine oxidase (MAO) is important for breaking down neurotransmitters and is a potential target for treating neurodegenerative diseases like depression and Alzheimer's.
  • The study examined chromone-based compounds to see how effectively they inhibit MAO-A and MAO-B, identifying several promising derivatives through molecular docking techniques.
  • A quantitative structure-activity relationship (QSAR) model was developed to predict the effectiveness of these compounds, showing strong validation with experimental data and highlighting key molecular features that enhance their inhibitory effects.
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Article Synopsis
  • * Enzymatic hydrolysis significantly increased protein solubility from under 3.1% to about 16%, with up to 87.73% hydrolysis achieved, particularly with the 1:2 enzyme ratio treatment.
  • * The treated yeast proteins showed better functionality, including increased surface area, emulsion stability, and an enhanced amino acid profile, suggesting potential for various food applications.
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Background: Enhancing maize grain yield in tropical regions faces significant challenges due to variability in agroclimate, soil conditions, and agroecosystems. Understanding genotype (G) by environment (E) interaction (GEI) in plant breeding is crucial for selecting and developing high-yielding genotypes adapted to diverse environments.

Methods: Ten maize hybrids, including eight candidates and two commercial varieties, were evaluated across ten environments in Indonesia using a randomized complete block design with three replications.

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Sperm acrosome-associated 1 (SPACA1) mRNA and protein molecules deficiency indicate low fertility and semen quality of Bali bulls (Bos sondaicus).

Theriogenology

February 2025

Cooperative Agriculture Research Center, College of Agriculture, Food and Natural Resources, Prairie View, A&M University, Prairie View, TX, United States. Electronic address:

Article Synopsis
  • Molecular biomarkers, specifically SPACA1, are linked to sperm fertility characteristics and may improve the accuracy of assessing bull fertility.
  • The study analyzed SPACA1 mRNA and protein levels in frozen semen from 20 Bali bulls, classified into high and low fertility groups, using various semen quality tests.
  • Results indicated that higher levels of SPACA1 are associated with better fertility rates and semen quality, suggesting its potential as a reliable biomarker for bull fertility.
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Background: Good sepsis management is key to successful sepsis therapy and optimal patient outcomes. Objectives: This study aimed to determine obstacles among nurses and doctors to implementing the hour-1 sepsis bundle in a secondary hospital in Indonesia.

Methods: This was a qualitative study with a phenomenological approach.

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D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care.

Crit Care

November 2024

Division of Perioperative, Acute, Critical Care and Emergency Medicine, Department of Medicine, University of Cambridge, Level 4, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

Article Synopsis
  • The D-PRISM study investigated global practices for diagnosing and treating pneumonia in ICU settings, focusing on community-acquired, hospital-acquired, and ventilator-associated pneumonia across different countries.
  • A survey gathered responses from 1,296 ICU clinicians across 72 countries, revealing varied diagnostic processes and a lack of standardized microbiological testing, particularly in lower-income regions.
  • Findings indicated that the typical antibiotic treatment duration was 5-7 days, with shorter durations linked to effective antimicrobial stewardship programs in higher-income countries.
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  • The study focuses on the nectar-feeding bat from Timor Island, examining the morphology and microstructure of its tongue's papillae using advanced microscopy techniques.
  • The tongue is divided into three parts: apex, corpus, and radix, each containing various types of papillae that serve different functions related to feeding.
  • The findings highlight the diversity of mechanical and sensory papillae on the bat's tongue, tailored to its specific dietary needs in its natural habitat.
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Aim: To evaluate the essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins through CD55 and CD59 on erythrocyte (TER-119).

Methods: Streptozotocin (145 mg/kg) was used to induce diabetes mice. In diabetes mellitus (DM) model mice were treated with MA formulation for 14 days at a D1 - 500 mg/kg (M) + 620 mg/kg BW (A), D2 - 1000 mg/kg (M) + 420 mg/kg (A), and D3 - 1500 mg/kg (M) + 200 mg/kg (A).

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Maize stands out as a versatile commodity, finding applications in food and animal feed industries. Notably, half of the total demand for maize is met through its utilization as animal feed. Despite its importance, maize cultivation often grapples with crop failures resulting from delayed disease management or insufficient knowledge about these diseases, impeding timely intervention.

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Growth and aging are fundamental elements of human development. Aging is defined by a decrease in physiological activities and higher illness vulnerability. Affected by lifestyle, environmental, and hereditary elements, aging results in disorders including cardiovascular, musculoskeletal, and neurological diseases, which accounted for 16.

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Article Synopsis
  • * A review of existing literature examined the effects of exercise on CV junction health, focusing on studies that measured outcomes like pain, mobility, and quality of life.
  • * The findings suggest that exercise-based rehabilitation programs are effective in improving symptoms and may aid in the management and prevention of CV junction problems.
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Article Synopsis
  • Schwannomas are benign tumors typically found near spinal nerve roots, but large cases with cystic degeneration are difficult to diagnose before surgery and are not well-researched in medical literature.
  • A case is presented of a 28-year-old man with a giant schwannoma causing intermittent pain in his left thigh; MRI revealed a complex cystic lesion extending from L4 to S1.
  • Successful surgical removal of the tumor led to symptom resolution, highlighting the need for accurate diagnosis through MRI and histopathology, and emphasizing that complete surgical excision is the preferred treatment approach.
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Article Synopsis
  • Coccidiosis is a major problem in the poultry industry, typically managed with synthetic antibiotics and disinfectants.
  • This study shows that Piper betle L essential oil (PBEO) can effectively combat Eimeria tenella, demonstrating up to 95.33% anticoccidial activity by disrupting oocyst walls and inhibiting sporulation.
  • Key compounds identified in PBEO, such as eugenol, highlight its potential as a natural alternative to conventional treatments, warranting further research into its applications against coccidian parasites.
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