4 results match your criteria: "Branch of IBMC "Scientific and Education Center"[Affiliation]"
Determination of Heterogeneous Proteomic and Metabolomic Response in anti-TNF and anti-IL-6 Treatment of Patients with Rheumatoid Arthritis.
Life (Basel)
February 2023
Biobanking Group, Branch of IBMC "Scientific and Education Center", 109028 Moscow, Russia.
Reduction in tumor necrosis factor (αTNF) and interleukin-6 (IL-6) activities is a widely utilized strategy for the treatment of rheumatoid arthritis (RA) with a high success rate. Despite both schemes targeting the deprivation of inflammatory reactions caused by the excessive activity of cytokines, their mechanisms of action and the final output are still unequal. This was a comparative longitudinal study that lasted for 24 weeks and aimed to find the answer to why the two schemes of therapy can pass out of proportion in attitude of their efficiency.
View Article and Find Full Text PDFMolecular Dynamics Study of Citrullinated Proteins Associated with the Development of Rheumatoid Arthritis.
Proteomes
February 2022
Biobanking Group, Branch of IBMC "Scientific and Education Center", 109028 Moscow, Russia.
Article Synopsis
- Protein post-translational modifications (PTMs) play a vital role in various cellular functions and their dysregulation is linked to diseases like rheumatoid arthritis (RA).
- The three key PTMs involved in RA include glycosylation, which influences antigen presentation, citrullination, which is closely linked to the presence of specific autoantibodies, and carbamylation.
- This study analyzed proteins with PTMs relevant to RA over the past 20 years, identifying target proteins, exploring their structural characteristics, and conducting molecular dynamics experiments to understand how these modifications may relate to the disease's development.
Sports Nutrition: Diets, Selection Factors, Recommendations.
Nutrients
October 2021
Biobanking Group, Branch of IBMC "Scientific and Education Center" Bolshoy Nikolovorobinsky Lane, 109028 Moscow, Russia.
Article Synopsis
- An athlete's diet is shaped by both external and internal factors that can affect their food intolerance or allergy symptoms during exercise.
- Food choices are dynamic and can change based on timing, location, and environmental conditions, necessitating personalized dietary guidance from healthcare professionals.
- Understanding athletes' nutritional strategies before and during training is crucial for identifying effective foods that can mitigate negative symptoms and enhance performance outcomes.
Biobanks-A Platform for Scientific and Biomedical Research.
Diagnostics (Basel)
July 2020
Biobanking Group, Branch of IBMC "Scientific and Education Center" Bolshoy Nikolovorobinsky lane, 7, 109028 Moscow, Russia.
The development of biomedical science requires the creation of biological material collections that allow for the search and discovery of biomarkers for pathological conditions, the identification of new therapeutic targets, and the validation of these findings in samples from patients and healthy people. Over the past decades, the importance and need for biobanks have increased considerably. Large national and international biorepositories have replaced small collections of biological samples.
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