10 results match your criteria: "Branch of Academic Center for Education[Affiliation]"

Comparison of Plasma Levels of MicroRNA-155-5p, MicroRNA-210-3p, and MicroRNA-16-5p in Rheumatoid Arthritis Patients with Healthy Controls in a Case-control Study.

Iran J Allergy Asthma Immunol

September 2023

Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran AND Cardiac Primary Prevention Research Center, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

Rheumatoid arthritis is a chronic autoimmune disease that causes inflammation and destruction of the joints. The objective of the current study was to evaluate the expression of microRNA (miR)-155-5p, miR-210-3p, and miR-16-5p in the plasma of patients with rheumatoid arthritis in comparison with a healthy control group to attain an expression profile for earlier diagnosis and treatment. To carry out this study, 100 individuals were chosen as two equally sized groups of rheumatoid arthritis patients and healthy controls.

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Article Synopsis
  • - Recent advancements in molecular diagnosis of allergies have led to the development of the friendly allergen nano-bead array (FABER), a multiplex assay that tests for specific IgE against 244 different allergens in a routine manner.
  • - A study involving 60 allergic patients assessed their IgE sensitization patterns using the FABER test, which identifies responses to both inhalant and food allergens.
  • - Results indicated that common allergenic sensitizations included certain grasses and their components, with findings showing higher rates of sensitization to specific grass proteins compared to previous extract-based tests.
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Article Synopsis
  • - The study evaluated the effectiveness of oral immunotherapy (OIT) for desensitizing patients with IgE-mediated egg white allergies by comparing clinical and laboratory results before and after treatment.
  • - Conducted on eight patients over six months, the results showed that all patients in the OIT group were desensitized and could tolerate 40 cc of raw egg white, unlike controls who failed the Oral Food Challenge.
  • - Findings revealed significant reductions in skin reaction and specific IgE levels post-OIT, indicating that this treatment could be a safe and effective method for managing egg allergies.
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Plasma Levels of MicroRNA-146a-5p, MicroRNA-24-3p, and MicroRNA-125a-5p as Potential Diagnostic Biomarkers for Rheumatoid Arthris.

Iran J Allergy Asthma Immunol

June 2021

Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran AND Cardiac Primary Prevention Research Center, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

Rheumatoid arthritis (RA) is an autoimmune disease that is characterized by inflammation of the articular tissue. This study aims to evaluate the expression of microRNA (miR)-146a-5p, miR-24-3p, and miR-125a-5p in the plasma of RA patients and compare them with those of healthy controls to obtain a specific expression profile for earlier diagnosis and assistance in treating patients. This study was performed on 50 RA patients and 50 healthy controls.

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Exosomal MicroRNAs as Biomarkers in Allergic Asthma.

Iran J Allergy Asthma Immunol

April 2021

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Allergy and Clinical Immunology, Pediatrics Center of Excellence, Children's Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Exosomes are extracellular vesicles that are involved in intracellular communication and different biological processes. Recently, the importance of microRNAs (miRNAs) in exosomes has been considered as biomarkers in asthma diagnosis. This study aimed to determine the expression of selective miRNAs from plasma-derived exosomes in moderate and severe asthmatic patients compared with healthy controls.

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The skin prick test (SPT) could be applied as a useful in vivo method for the detection of sensitization in epidemiological and diagnostic studies if the wheal size is ideally evaluated. We focused on SPT wheal size to identify sensitization pattern to common inhalant and food allergens. In this cross-sectional study, SPT results were obtained from a total of 972 allergic patients.

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Background: T-cell response outcome is determined by co-stimulatory/inhibitory signals. Programmed cell death-1 ligand-1 (PD-L1) is a member of these co-signaling molecules with known soluble form in human serum. Soluble PD-L1 (sPD-L1) is also recognized in patients with some types of malignancy or autoimmune disorders, though there are few studies on sPD-L1 roles in allergic diseases.

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Objective: The aim of this study is assessment of effects of different assisted reproductive techniques (ART) like in vitro fertilization (IVF) and intra cytoplasmic sperm injection (ICSI) on prelinguistic behavior of infants conceived by these techniques.

Methods: In this descriptive, cross sectional study, prelinguistic behavior of 151 full term ART infants of Royan Institute have been assessed in Children's Health and Development Research Center of Tehran from August 2007 until August 2009. Questionnaires were completed by parents at 9 months old.

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Objective: Due to recent scientific progress in assisted reproductive techniques (ART), infertile couples can now become fertile. Thus, a number of infants in our country are the results of these costly interventions. This study has been undertaken to evaluate the physical growth process of different methods of ART infants by standard growth charts from birth until nine months of age.

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Congenital anomalies in infants conceived by assisted reproductive techniques.

Arch Iran Med

April 2012

Child Health and Development Research Department, Tehran Medical Sciences, Branch of Academic Center for Education, Culture and Research (ACECR), Tehran, Iran.

Background: Many studies show that congenital defects in infants conceived by assisted reproductive techniques (ART) are more than infants of normal conception (NC). The aim of this study is to determine the frequency of congenital anomalies in ART infants from Royan Institute and to compare congenital anomalies between two ART techniques. 

Methods: In a cross-sectional descriptive study, 400 ART infants from Royan Institute who resided in Tehran were selected by non-random, consecutive sampling.

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