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Effects of low-frequency ultrasound combined with microbubbles on benign prostate hyperplasia.

Can Urol Assoc J

November 2013

Department of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated 6th People's Hospital, Shanghai Institute of Ultrasound in Medicine, Shanghai, PR China; ; Department of Ultrasound in Medicine, Branch Hospital in Fengxian of Shanghai 6th People's Hospital, Shanghai, PR China.

Introduction: Our objective is to assess the effects of low-frequency ultrasound combined with microbubbles on benign prostate hyperplasia (BPH).

Methods: Sixteen Beagle dogs with BPH were randomly assigned into 4 groups (n = 4): control group (without treatment), G1 group (injection with 2 mL of microbubble contrast agent); G2 group (21 kHz ultrasound); and G3 group (injection with 2 mL of micro-bubble contrast agent +21 kHz ultrasound). The histopathological damage to prostate cells was assessed via transmission electron microscopy and optical microscopy.

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