141 results match your criteria: "Brain and Consciousness Research Center[Affiliation]"

A Geometrical Account to Explain the Fat-Face Illusion.

Iperception

December 2020

Graduate Institute of Mind, Brain, & Consciousness, Taipei Medical University, Taipei City.

Investigations of the "fat-face" illusion have unanimously agreed that the illusion is face-specific. Here, we offer several manipulations to highlight that the fat-face illusion is not restricted to the bottom image, isn't a property of internal features, facial contour/texture, and in general isn't even specific to faces. We propose the axis of horizontal asymmetry account to contextualize fat-face illusion as a geometry-led illusion.

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Bipolar disorder (BD) shows complex alterations in psychomotor, affective, and thought dimensions, as described by Kraepelin in his fundamental model of manic-depressive illness. In turn, the expression of behavioral/phenomenological dimensions is traceable to intrinsic brain activity. We reported a data overview on intrinsic brain functioning and its changes in BD.

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Evidence suggests divergent thinking is the cognitive basis of creative thoughts. Neuroimaging literature using resting-state functional connectivity (RSFC) has revealed network reorganizations during divergent thinking. Recent studies have revealed the changes of network organizations when performing creativity tasks, but such brain reconfigurations may be prolonged after task and be modulated by the trait of creativity.

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The associations of F-THK5351 tau positron emission tomography (PET) findings with core domains of progressive supranuclear palsy (PSP) and its diagnostic certainty have yet to be fully elucidated. The F-THK5351 PET patterns of 17 patients with PSP (68.9 ± 6.

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Altered EEG Signal Complexity Induced by Hand Proximity: A Multiscale Entropy Approach.

Front Neurosci

October 2020

Brain and Consciousness Research Center, TMU-Shuang Ho Hospital, New Taipei City, Taiwan.

Visual short-term memory (VSTM) is an important cognitive function that acts as a temporary storage for visual information. Previous studies have shown that VSTM capacity can be modulated by the location of one's hands, where hand proximity enhances neural processing and memory of nearby visual stimuli. The present study used traditional event-related potentials (ERP) along with multiscale entropy (MSE) analysis to shed light on the neural mechanism(s) behind such near-hand effect.

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Distress calls are an acoustically variable group of vocalizations ubiquitous in mammals and other animals. Their presumed function is to recruit help, but there has been much debate on whether the nature of the disturbance can be inferred from the acoustics of distress calls. We used machine learning to analyse episodes of distress calls of wild infant chimpanzees.

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Bereavement, the experience of losing a loved one, is one of the most catastrophic but inevitable events in life. It causes grief and intense depression-like sadness. Recent studies have revealed the effectiveness and proficiency of mindfulness-based cognitive therapy (MBCT) in emotional regulation among bereavement populations.

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Impulsivity is a multi-faceted construct that underpins various mental health disorders. Impulsive behavior exacts a substantial health and economic burden, hence the importance of developing specific interventions to target impulsivity. Two forms of non-invasive brain stimulation, namely transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), have been used to modulate impulsivity.

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Depression is associated with disconnection of neurotransmitter-related nuclei in multiple sclerosis.

Mult Scler

June 2021

Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA/Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Section of Neurology, University of Genoa, Genoa, Italy/Ospedale Policlinico San Martino IRCCS, Genoa, Italy.

Background: Depression is frequently associated with multiple sclerosis (MS). However, the biological background underlying such association is poorly understood.

Objective: Investigating the functional connections of neurotransmitter-related brainstem nuclei, along with their relationship with white matter (WM) microstructure, in MS patients with depressive symptomatology (MS-D) and without depressive symptomatology (MS-nD).

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Variation of picture angles and its effect on the Concealed Information Test.

Cogn Res Princ Implic

July 2020

Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, No.250, Wuxin St., Taipei City, 11031, Taiwan.

Background: The reaction time-based Concealed Information Test (RT-CIT) is a memory paradigm used to detect crime-related knowledge. However, this would also imply that the RT-CIT would be vulnerable to factors that are known to compromise object recognition or memory integrity. From this perspective, one key issue is whether "guilty" memory can be detected if the crime-related images are photographed at different angles from what the perpetrator saw, which is almost always the case in the field.

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Sertraline is one of the most commonly prescribed antidepressants. Major depressive disorder (MDD) is characterized by spontaneous thoughts that are laden with negative affect-a "malignant sadness". Prior neuroimaging studies have identified abnormal resting-state functional connectivity (rsFC) in the spontaneous brain networks of MDD patients.

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Article Synopsis
  • * A study involving twelve chronic stroke patients assessed brain activity using fMRI before, after, and one month post-rehabilitation, comparing them with age-matched normal controls.
  • * Results showed improved motor performance and significant enhancement in brain connectivity between networks, particularly between the posterior cingulate cortex and primary motor cortex, indicating that cross-network interactions can be used as biomarkers for evaluating rehabilitation interventions.
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Psychomotor abnormalities have been abundantly observed in psychiatric disorders like major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCH). Although early psychopathological descriptions highlighted the truly psychomotor nature of these abnormalities, more recent investigations conceive them rather in purely motor terms. This has led to an emphasis of dopamine-based abnormalities in subcortical-cortical circuits including substantia nigra, basal ganglia, thalamus, and motor cortex.

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Objective: To investigate whether dynamic cerebral autoregulation (CA) and neuroimaging characteristics are determinants of poststroke cognitive impairment (PSCI).

Methods: Eighty patients within 7 days of acute ischemic stroke and 35 age- and sex-matched controls were enrolled. In the patients with stroke, brain magnetic resonance imaging and dynamic CA were obtained at baseline, and dynamic CA was followed up at 3 months and 1 year.

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One of the hardest problems in studying animal behaviour is to quantify patterns of social interaction at the group level. Recent technological developments in global positioning system (GPS) devices have opened up new avenues for locating animals with unprecedented spatial and temporal resolution. Likewise, advances in computing power have enabled new levels of data analyses with complex mathematical models to address unresolved problems in animal behaviour, such as the nature of group geometry and the impact of group-level interactions on individuals.

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Somebody is home.

Cogn Neuropsychol

September 2020

Graduate Institute of Mind, Brain, and Consciousness, Taipei Medical University, Taipei, Taiwan.

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The opioidergic system and intrinsic brain activity, as organized in large-scale networks such as the salience network (SN), sensorimotor network (SMN), and default-mode network (DMN), play core roles in healthy behavior and psychiatric disorders. This work aimed to investigate how opioidergic signaling affects intrinsic brain activity in healthy individuals by reviewing relevant neuroanatomical, molecular, functional, and pharmacological magnetic resonance imaging studies in order to clarify their physiological links and changes in psychiatric disorders. The SN shows dense opioidergic innervations of subcortical structures and high expression levels of opioid receptors in subcortical-cortical areas, with enhanced or reduced activity with low or very high doses of opioids, respectively.

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Opposing Changes in the Functional Architecture of Large-Scale Networks in Bipolar Mania and Depression.

Schizophr Bull

July 2020

University of Ottawa Brain and Mind Research Institute, and Mind Brain Imaging and Neuroethics Royal's Institute of Mental Health Research, University of Ottawa, Ottawa, ON, Canada.

Objective: Manic and depressive phases of bipolar disorder (BD) show opposite symptoms in psychomotor, thought, and affective dimensions. Neuronally, these may depend on distinct patterns of alterations in the functional architecture of brain intrinsic activity. Therefore, the study aimed to characterize the spatial and temporal changes of resting-state activity in mania and depression, by investigating the regional homogeneity (ReHo) and degree of centrality (DC), in different frequency bands.

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Intrinsic brain activity of subcortical-cortical sensorimotor system and psychomotor alterations in schizophrenia and bipolar disorder: A preliminary study.

Schizophr Res

April 2020

Mind Brain Imaging and Neuroethics Royal's Institute of Mental Health Research, University of Ottawa, Ottawa, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, Canada; Centre for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China; Mental Health Centre, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China. Electronic address:

Objective: Alterations in psychomotor dimension cut across different psychiatric disorders, such as schizophrenia (SCZ) and bipolar disorder (BD). This preliminary study aimed to investigate the organization of intrinsic brain activity in the subcortical-cortical sensorimotor system in SCZ (and BD) as characterized according to psychomotor dimension.

Method: In this resting-state functional magnetic resonance imaging (fMRI) study, functional connectivity (FC) between thalamus and sensorimotor network (SMN), along with FC from substantia nigra (SN) and raphe nuclei (RN) to basal ganglia (BG) and thalamic regions, were investigated by using an a-priori-driven and dimensional approach.

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Objectives: We aimed to analyze the effects of multidomain attention training on alertness, sustained attention, and visual-spatial attention in older adults with mild cognitive impairment (MCI).

Design: The design used in this study was a two-arm, parallel group, double-blind randomized controlled trial.

Setting And Participants: The participants of the study were seventy-eight older adults with MCI (mean age: 79.

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The Sequin Illusion.

Iperception

November 2019

Graduate Institute of Mind, Brain, & Consciousness, Taipei Medical University, Taipei City; Brain and Consciousness Research Center, TMU-Shuang Ho Hospital, New Taipei City.

The Sequin Illusion can be seen when shapes are drawn in dotted lines, against a background of different brightness. This can be done either with bright dots over a dark background or with dark dots over a bright background, though the latter usually works better. The illusion appears as a wave of dark (or bright) spots inside the dotted shapes (like sequins!) in peripheral vision.

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Temporal Preparation, Impulsivity and Short-Term Memory in Depression.

Front Behav Neurosci

November 2019

Graduate Institute of Medical Humanities, College of Humanities and Social Sciences, Taipei Medical University, Taipei, Taiwan.

Patient suffering of major depressive disorder (MDD) often complain that subjective time seems to "drag" with respect to physical time. This may point toward a generalized dysfunction of temporal processing in MDD. In the present study, we investigated temporal preparation in MDD.

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Purpose: Resting-state functional MRI (rs-FMRI) has shown potential for presurgical mapping of eloquent cortex when a patient's performance on task-based FMRI is compromised. The seed-based analysis is a practical approach for detecting rs-FMRI functional networks; however, seed localization remains challenging for presurgical language mapping. Therefore, we proposed a data-driven approach to guide seed localization for presurgical rs-FMRI language mapping.

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