141 results match your criteria: "Brain and Consciousness Research Center[Affiliation]"

The coexistence of correlated electron and hole crystals enables the realization of quantum excitonic states, capable of hosting counterflow superfluidity and topological orders with long-range quantum entanglement. Here we report evidence for imbalanced electron-hole crystals in a doped Mott insulator, namely, α-RuCl, through gate-tunable non-invasive van der Waals doping from graphene. Real-space imaging via scanning tunnelling microscopy reveals two distinct charge orderings at the lower and upper Hubbard band energies, whose origin is attributed to the correlation-driven honeycomb hole crystal composed of hole-rich Ru sites and rotational-symmetry-breaking paired electron crystal composed of electron-rich Ru-Ru bonds, respectively.

View Article and Find Full Text PDF
Article Synopsis
  • Various COVID-19 vaccines, including viral vector, mRNA, and inactivated types, have been linked to central nervous system inflammatory demyelinating diseases (CNS IDDs), with a case study highlighting the AstraZeneca vaccine and 78 other reported cases.
  • The majority of the CNS IDD cases involved patients who received viral vector vaccines (62%), followed by mRNA (25.3%) and inactivated vaccines (12.7%), with male patients being more affected by viral vector vaccines.
  • The study identified significant correlations between vaccine type, age, gender, and the presence of specific autoantibodies (like anti-MOG and anti-AQP4), suggesting the need for further research to understand underlying mechanisms and guide
View Article and Find Full Text PDF

DLPFC-PPC-cTBS effects on metacognitive awareness.

Cortex

October 2023

Graduate Institute of Mind, Brain and Consciousness (GIMBC), Taipei Medical University, Taipei, Taiwan; Brain and Consciousness Research Center (BCRC), TMU-Shuang Ho Hospital, New Taipei City, Taiwan. Electronic address:

Background: Neuroimaging and lesion studies suggested that the dorsolateral prefrontal and posterior parietal cortices mediate visual metacognitive awareness. The causal evidence provided by non-invasive brain stimulation, however, is inconsistent.

Objective/hypothesis: Here we revisit a major figure discrimination experiment adding a new Kanizsa figure task trying to resolve whether bilateral continuous theta-burst transcranial magnetic stimulation (cTBS) over these regions affects perceptual metacognition.

View Article and Find Full Text PDF

The paper presents the application of a phase-sensitive optical time-domain reflectometer (phi-OTDR) in the field of urban infrastructure monitoring. In particular, the branched structure of the urban network of telecommunication wells. The encountered tasks and difficulties are described.

View Article and Find Full Text PDF

Human microsaccade cueing modulation in visual- and memory-delay saccade tasks after theta burst transcranial magnetic stimulation over the frontal eye field.

Neuropsychologia

August 2023

Eye-Tracking Laboratory, Brain and Consciousness Research Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Institute of Cognitive Neuroscience, College of Health Science and Technology, National Central University, Taoyuan City, Taiwan; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan; Department of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan. Electronic address:

Microsaccades that occur during periods of fixation are modulated by various cognitive processes and have an impact on visual processing. A network of brain areas is involved in microsaccade generation, including the superior colliculus and frontal eye field (FEF) which are involved in modulating microsaccade rate and direction after the appearance of a visual cue (referred to as microsaccade cueing modulation). Although the neural mechanisms underlying microsaccade cueing modulations have been demonstrated in monkeys, limited research has investigated a causal role of these areas in humans.

View Article and Find Full Text PDF

Obstructive sleep apnea (OSA) with a low arousal threshold (low-ArTH) phenotype can cause minor respiratory events that exacerbate sleep fragmentation. Although anthropometric features may affect the risk of low-ArTH OSA, the associations and underlying mechanisms require further investigation. This study investigated the relationships of body fat and water distribution with polysomnography parameters by using data from a sleep center database.

View Article and Find Full Text PDF

Structural or crystal asymmetry is a necessary condition for the emergence of zero-bias photocurrent in light detectors. Structural asymmetry has been typically achieved via p-n doping, which is a technologically complex process. Here, we propose an alternative approach to achieve zero-bias photocurrent in two-dimensional (2D) material flakes exploiting the geometrical nonequivalence of source and drain contacts.

View Article and Find Full Text PDF
Article Synopsis
  • Sleep inertia (SI) is the groggy feeling you get when you wake up, making it hard to think quickly and focus.
  • Scientists studied how the brain works when people wake up by using special brain imaging techniques and tasks to see how well they can pay attention.
  • Their results showed that the brain's activity affects how quickly people get back to normal after waking up, and this research helps us understand what happens in our brains when we wake up from sleep.
View Article and Find Full Text PDF

Information geometry and synchronization phase transition in the Kuramoto model.

Phys Rev E

April 2023

Moscow Institute of Physics and Technology, Dolgoprudny 141700, Russia; Institute for Information Transmission Problems, Moscow 127994, Russia; and Laboratory of Complex Networks, Brain and Consciousness Research Center, Moscow, Russia.

We discuss how the synchronization in the Kuramoto model can be treated in terms of information geometry. We argue that the Fisher information is sensitive to synchronization transition; specifically, components of the Fisher metric diverge at the critical point. Our approach is based on the recently proposed relation between the Kuramoto model and geodesics in hyperbolic space.

View Article and Find Full Text PDF

Thalamocortical coherence predicts persistent postconcussive symptoms.

Prog Neurobiol

July 2023

Translational Imaging Research Center, Taipei Medical University Hospital, Taipei 11031, Taiwan; Department of Medical Imaging, Taipei Medical University Hospital, Taipei 11031, Taiwan; Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Research Center for Artificial Intelligence in Medicine, Taipei Medical University, Taipei 11031, Taiwan. Electronic address:

The pathogenetic mechanism of persistent post-concussive symptoms (PCS) following concussion remains unclear. Thalamic damage is known to play a role in PCS prolongation while the evidence and biomarkers that trigger persistent PCS have never been elucidated. We collected longitudinal neuroimaging and behavior data from patients and rodents after concussion, complemented with rodents' histological staining data, to unravel the early biomarkers of persistent PCS.

View Article and Find Full Text PDF

Neural oscillations have been categorized into various frequency bands that are mechanistically associated with different cognitive functions. Specifically, the gamma band frequency is widely implicated to be involved in a wide range of cognitive processes. As such, decreased gamma oscillation has been associated with cognitive declines in neurological diseases, such as memory dysfunction in Alzheimer's disease (AD).

View Article and Find Full Text PDF

Graphene shows strong promise for the detection of terahertz (THz) radiation due to its high carrier mobility, compatibility with on-chip waveguides and transistors, and small heat capacitance. At the same time, weak reaction of graphene's physical properties on the detected radiation can be traced down to the absence of a band gap. Here, we study the effect of electrically induced band gap on THz detection in graphene bilayer with split-gate p-n junction.

View Article and Find Full Text PDF

Introduction: Although abundant research delving into the acute exercise-induced modulation of cognitive performance and the P300-ERP component has been conducted, there is a lack of consensus regarding whether or not this type of intervention has a beneficial effect on cognition and how it relates to the P300-ERP.

Methods: To examine the possible sources of this discrepancy, we conducted a meta-analysis of ERP results together with cognitive performance that were systemically stratified by relevant demographic and methodological moderators.

Results: Our results indicate that while acute exercise exerted an overall stable effect on cognitive improvement, associated with enlarged P300 amplitudes, the effect size varied across factors of age, biological sex, exercise intensity, exercise type, control type, and experimental design.

View Article and Find Full Text PDF

Revisiting the effects of exercise on cerebral neurovascular functions in rats using multimodal assessment techniques.

iScience

April 2023

Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, No. 35 Keyan Road, Zhunan Town, Miaoli County 35053, Taiwan.

Physical activity in the form of aerobic exercise has many beneficial effects on brain function. Here, we aim to revisit the effects of exercise on brain morphology and neurovascular organization using a rat running model. Electrocorticography (ECoG) was integrated with laser speckle contrast imaging (LSCI) and applied to simultaneously detect CSD propagation and the corresponding neurovascular function.

View Article and Find Full Text PDF

Mindfulness refers to a mental state of awareness of internal experience without judgment. Studies have suggested that each mindfulness practice may involve a unique mental state, but the underlying neurophysiological mechanisms remain unknown. Here we examined how distinct mindfulness practices after mindfulness-based intervention alter brain functionality.

View Article and Find Full Text PDF

Noise-induced hearing loss profile among Taiwan Airforce on duty pilots.

Am J Otolaryngol

May 2023

Graduate Institute of Injury Prevention and Control, College of Public Health, Taipei Medical University, Taipei 110, Taiwan; Brain and Consciousness Research Center, Shuang-Ho Hospital, Taipei Medical University, New Taipei City 234, Taiwan; Graduate Institute of Mind, Brain and Consciousness, College of Humanities and Social Sciences, Taipei Medical University, Taipei 110, Taiwan; Psychiatric Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan. Electronic address:

Purpose: Noise-induced hearing loss (NIHL) often results in impaired functional hearing and accidental injuries; thus, reducing military performance and endangering flight safety. While a few studies addressing laterality (left-right ear differences) and NIHL incidence between fixed-winged (jet-fighter) and rotary-wing (helicopter) aircrafts yielded inconsistent results, little is known about the NIHL profile among different types of jet-fighter pilots. This study aims to conduct a fine-grained examination of NIHL among Airforce jet pilots, with planned comparisons of laterality and aircraft type, along with the goal to compare the sensitivity of different hearing indices in predicting military pilot NIHL.

View Article and Find Full Text PDF

Patients with Type 2 diabetes are known to be more susceptible to experience dementia and depression/anxiety. The neural circuits of emotional conflict monitoring, as indicated by a Stroop task, might become altered in terms of cognitive and affective impairments in diabetes. This study investigated alterations in the emotional conflict monitoring and associations of corresponding brain activities with metabolic parameters in persons with Type 2 diabetes.

View Article and Find Full Text PDF

Practicing mindfulness, focusing attention on the internal and external experiences occurring in the present moment with open and nonjudgement stance, can lead to the development of emotional regulation skills. Yet, the effective connectivity of brain regions during mindfulness has been largely unexplored. Studies have shown that mindfulness practice promotes functional connectivity in practitioners, potentially due to improved emotional regulation abilities and increased connectivity in the lateral prefrontal areas.

View Article and Find Full Text PDF

Background: Evidence on the long-term comparative effectiveness of posttraumatic stress disorder (PTSD) psychotherapies in adults remains unknown. Therefore, we performed an extensive network meta-analysis of randomised controlled trials (RCTs) to determine the comparative effectiveness of psychotherapies for people diagnosed with PTSD.

Methods: A comprehensive search was conducted in Cochrane library, Embase, Medline-OVID, PubMed, Scopus, and Psych-Info until March 2021.

View Article and Find Full Text PDF

Acute sleep deprivation exacerbates systemic inflammation and psychiatry disorders through gut microbiota dysbiosis and disruption of circadian rhythms.

Microbiol Res

March 2023

Graduate Institute of Biotechnology, National Chung Hsing University, Taichung 402, Taiwan; Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan. Electronic address:

Article Synopsis
  • * A study using mice showed that after 72 hours of sleep deprivation, there was increased appetite but decreased body weight, along with anxiety-like behaviors and changes in gut microbiota composition.
  • * The sleep-deprived mice exhibited higher inflammation levels, changes in circadian rhythm regulation, and gut barrier dysfunction compared to control mice, indicating complex interactions between sleep deprivation, inflammation, and microbiota.
View Article and Find Full Text PDF

Photoconductivity of novel materials is the key property of interest for design of photodetectors, optical modulators, and switches. Despite the photoconductivity of most novel 2d materials having been studied both theoretically and experimentally, the same is not true for 2d p-n junctions that are necessary blocks of most electronic devices. Here, we study the sub-terahertz photocoductivity of gapped bilayer graphene with electrically induced p-n junctions.

View Article and Find Full Text PDF

Human economic decision-making sometimes appears to be irrational. Partly, this is due to cognitive biases that can lead to suboptimal economic choices and context-dependent risk-preferences. A pertinent question is whether such biases are part of our evolutionary heritage or whether they are culturally acquired.

View Article and Find Full Text PDF

The pupil constricts in response to an increase in global luminance level, commonly referred to as the pupil light reflex. Recent research has shown that these reflex responses are modulated by high-level cognition. There is larger pupil constriction evoked by a bright stimulus when the stimulus location spatially overlaps with the locus of attention, and these effects have been extended to saccade planning and working memory (here referred to as pupil local-luminance modulation).

View Article and Find Full Text PDF

Neuromodulation of the right temporoparietal junction alters amygdala functional connectivity to authority pressure.

Hum Brain Mapp

December 2022

Graduate Institute of Injury Prevention and Control, College of Public Health, Taipei Medical University, Taipei, Taiwan.

Past historical events and experimental research have shown that complying with orders from an authority has a strong impact on harming/destructive behavior, but no one has ever looked into the potential intervention and its neural underpinning to reveal the toll of coercion. We used a paradigm of virtual obedience to authority, in which an experimenter ordered a volunteer to press a handheld button to initiate actions that carried different consequences, including harming or helping others. In this study, we scanned the brain with functional neuroimaging and applied transcranial direct current stimulation (tDCS) to modulate the activation of the right temporoparietal junction (rTPJ) in healthy volunteers in a single-blinded, sham-controlled, crossover trial with anodal, cathodal, and sham stimulation.

View Article and Find Full Text PDF
Article Synopsis
  • Psychological factors, especially anxiety and positive emotions, significantly affect how healthy individuals and patients perceive respiratory symptoms, with heightened anxiety linked to reduced respiratory sensory gating in the brain.
  • Using functional MRI, a study was conducted to understand how positive emotions influence respiratory sensory gating, hypothesizing that positive stimuli would lead to less brain activation in certain cortical areas compared to neutral stimuli.
  • Results indicated a general decrease in brain activity when moving from neutral to positive emotional conditions, though no significant difference was found in specific areas like the thalamus and primary visual cortices between pleasant emotional stimuli.
View Article and Find Full Text PDF