1,698 results match your criteria: "Brain Imaging in Venous Sinus Thrombosis"

Objective: We aim to provide a pictorial representation of the broad spectrum of intracranial hemorrhages associated with cerebral venous thrombosis (CVT), emphasizing atypical locations and rare intracerebral hemorrhage (ICH) types. We also hypothesize the pathophysiology leading to atypical locations of the ICH in CVT and the outcomes with anticoagulation therapy.

Background: ICH complicates about 40% of cases with CVT and is known to cause various types of ICH, including subarachnoid hemorrhage (SAH) and subdural hemorrhage (SDH).

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  • Cerebral sinus venous thrombosis (CSVT) is a serious condition in premature infants that can lead to complications like intraventricular hemorrhage if not diagnosed early.
  • A case study demonstrated that serial cranial ultrasounds can effectively detect CSVT early, allowing for timely intervention.
  • The use of anticoagulant therapy led to successful clot resolution, highlighting cranial ultrasound's importance as a diagnostic tool when MRI isn't available.
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Efficacy and Safety of a Dedicated Device for Cerebral Venous Thrombectomy: A Pilot Randomized Clinical Trial.

Stroke

January 2025

Department of Neurosurgery and Neurology (Y.X., B.S., C.L., C.W., J.D., R.M., F.Y., J.C., X.J.), Xuanwu Hospital, Capital Medical University.

Background: Lack of a dedicated thrombectomy device for cerebral venous thrombosis hinders the recanalization ability of endovascular treatment (EVT). Novel NiTi-braided stent retriever (Venous-TD) is a dedicated venous sinus thrombectomy device. This study aims to demonstrate the safety and efficacy of Venous-TD.

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Background And Purpose: Cranial venous outflow insufficiency, a model of brain dysfunction based on partial or intermittent obstruction to cranial venous drainage, is an attempt to explain a clinical phenotype characterised by multiple complex symptoms, including headache, fatigue and cognitive dysfunction, that can be responsible for long term neurological disability. This concept, however, has been received with some scepticism first, because its supposed symptoms seem mainly non-organic and, secondly, because its supposed lesions can be regarded as no more than variants of normal craniocervical venous anatomy. This reasoning, however, fails to appreciate that an understanding of normal venous anatomy has evolved, not from dedicated studies in healthy volunteers, but almost entirely from patients whose symptoms are assumed to be non-organic, or at least not referrable to the specifics of craniocervical venous anatomy.

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  • * Out of 179 SLE patients studied, 55% reported headaches, with the most common types being tension-type (65%) and migraines (27%), while no lupus-specific headaches were identified.
  • * The study found that patients with headaches had higher disease activity scores and a notable association between migraines and the presence of antiphospholipid antibodies, although neurological issues were not statistically significant despite being more prevalent in the headache group.
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  • The study aimed to characterize perinatal intracranial hemorrhage (pICH), focusing on differences between cases diagnosed before and after birth and analyzing their causes and clinical patterns.
  • Conducted over a decade, the research included 110 pICH cases, revealing that intraventricular hemorrhage (IVH) was most prevalent, particularly in prenatally diagnosed cases, while subpial hemorrhage was exclusively identified postnatally.
  • The findings indicated that genetic disorders contributed to nearly a third of pICH cases, highlighting the necessity for next-generation sequencing to better understand genetic factors associated with prenatally diagnosed hemorrhages.
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Update on management of cerebral venous thrombosis.

Curr Opin Neurol

October 2024

Faculdade de Medicina, Universidade de Lisboa.

Article Synopsis
  • This review focuses on improving the understanding and management of cerebral venous thrombosis (CVT), particularly in light of recent studies and emerging risk factors linked to the pandemic.
  • Key diagnostic tools include contrast-enhanced MRI and susceptibility-weighted imaging, which enhance the detection of vein thrombosis, while anticoagulants like dabigatran are found to be as effective as warfarin for long-term treatment.
  • Despite varying outcomes, a significant number of patients with CVT can experience recovery; about 80% achieve good functional status, though many may still face lingering symptoms affecting their quality of life.
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Special Considerations for Cross-Sectional Imaging in the Child with Neurovascular Disease.

Neuroimaging Clin N Am

November 2024

Division of Neuroradiology, Department of Diagnostic and Interventional Radiology, The Hospital for Sick Children, 170 Elizabeth Street, Toronto, Ontario M5G 1E8, Canada; Department of Medical Imaging, University of Toronto, 263 McCaul Street, 4th Floor, Toronto, Ontario M5T 1W7, Canada. Electronic address:

Article Synopsis
  • Pediatric neurovascular diseases are serious conditions that can lead to significant health problems and even death.
  • These diseases show a wide range of symptoms, from urgent neurological issues to long-term cognitive and developmental challenges, making accurate diagnosis important.
  • The article reviews the imaging techniques used to diagnose these diseases and highlights common findings observed in pediatric patients.
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  • - The study focuses on the rise of invasive fungal sinusitis, particularly mucormycosis, in post-COVID-19 patients in India, highlighting the importance of early diagnosis through neuroimaging to improve survival rates.
  • - Researchers analyzed MR imaging from 91 confirmed cases, finding that over half of the patients (51.6%) had advanced disease with intracranial spread, with significant complications such as cavernous sinus involvement and osteomyelitis.
  • - The results showed that unlike non-COVID-19 cases, there were no instances of certain severe complications like thrombosis in the studied COVID-19-associated cases, emphasizing unique patterns in disease manifestation.
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Central Nervous System Imaging in Rheumatic Diseases.

Rheum Dis Clin North Am

November 2024

Department of Rheumatic and Immunologic Diseases, Cleveland Clinic Lerner College of Medicine, Center for Vasculitis Care & Research, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address:

Article Synopsis
  • Rheumatic diseases can lead to various central nervous system (CNS) issues, including strokes, seizures, and headaches, along with demyelinating conditions like optic neuritis.* -
  • CNS problems often occur alongside other systemic symptoms of the rheumatic disease, but in some cases, neurological symptoms may be the first indication of the disease.* -
  • The review focuses on different rheumatic diseases that affect the CNS and highlights neuroimaging findings in affected patients.*
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Retrograde cerebral venous thrombosis (CVT) is a rare complication following internal jugular vein (IJV) ligation. The patient described in this report is a male in his 30s with locally advanced carcinoma tongue. He underwent near-total glossectomy and bilateral neck dissection.

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  • Cerebral venous thrombosis (CVT) is a rare but varied condition in children, with limited research available specifically focused on this demographic.
  • A study conducted from 2003 to 2021 at a Portuguese hospital analyzed 12 pediatric patients, most commonly presenting with symptoms like vomiting and headaches, often triggered by infections.
  • The study found that MRI is the best diagnostic tool for CVT in children, and initiating anticoagulant therapy significantly helps in reducing mortality and long-term neurological issues, although 30% of the patients experienced lasting effects.
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  • cSAH is a rare type of subarachnoid hemorrhage that presents a challenge in diagnosing cerebral venous sinus thrombosis (CVST), especially since they may occur together.
  • A case study of a 56-year-old woman shows that CVST can be identified through magnetic resonance venography (MRV) and genetic testing, revealing mutations in specific genes.
  • The paper stresses the need for advanced imaging to diagnose CVST and outlines an effective treatment plan involving anticoagulants like Enoxaparin, Warfarin, and Rivaroxaban to improve patient management.
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  • Herpes encephalitis is a serious illness caused by the herpes virus, affecting the brain and can lead to complications like blood clots in the brain (cerebral venous thrombosis or CVT).
  • A 14-year-old girl showed symptoms like confusion, headaches, and fever, leading doctors to suspect encephalitis; tests later confirmed she had HSV-1 causing her illness.
  • She was treated with special medications, but had some side effects, and doctors learned that CVT can happen along with herpes encephalitis, even though it's not common.
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Background: The appearance of cerebral venous sinus thrombosis (CVST) in childhood acute lymphocytic leukemia (ALL) is a rare life-threatening disease that can cause significant morbidity, neurological sequelae, and potentially poor outcomes.

Case Presentation: We present the case of a 13-year-old boy with ALL who developed CVST and intrinsic hemorrhage approximately 30 days after receiving chemotherapy with vincristine, dexamethasone, daunorubicin, and pegylated-asparaginase (PEG-Asp). He complained of a severe headache and then developed a generalized seizure at night.

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  • Scrub typhus is a disease caused by mites and is common in the Asia Pacific, leading to serious neurological problems like meningoencephalitis and, in rare cases, CVST.
  • A unique case involved an 18-year-old pregnant woman in India who, after experiencing symptoms like fever and headaches, was found to have CVST stemming from scrub typhus meningoencephalitis; treatment involved azithromycin and later anticoagulation therapy.
  • The report emphasizes the need to consider CVST in pregnant women with severe scrub typhus symptoms even if antibiotics are being used, as early treatment is crucial for better outcomes.
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  • - Post-traumatic cerebral venous sinus thrombosis (ptCVST) is often underdiagnosed in severe traumatic brain injury (TBI) patients due to non-specific symptoms that mimic TBI manifestations, making early detection critical for effective treatment.
  • - The study follows a 66-year-old male with moderate TBI who showed initial improvement in brain scans despite worsening clinical symptoms; this led to the diagnosis of ptCVST through brain CT venography after suspicious findings arose.
  • - There are currently no established guidelines for managing ptCVST, so treatment mainly focuses on controlling intracranial pressure and ensuring normal cerebral perfusion, highlighting the importance of recognizing signs that could indicate this complication.
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Dural arteriovenous fistulae in a 6-year-old girl with trisomy 21 and congenital heart disease.

Clin Neurol Neurosurg

November 2024

Department of Pediatrics, Graduate School of Medical Sciences,  Kyushu University, Fukuoka, Japan.

Dural arteriovenous fistula (DAVF) represents a pathological group of intracranial shunts arising from the dural artery to venous sinus and veins. Childhood-onset DAVF is generally considered to be poor in prognosis, whereas only limited information is available for the onset and long-term outcomes. We herein report a Japanese girl with trisomy 21, large ventricular septal defects, and pulmonary vein stenosis, for which a transcatheter stent had been placed after birth.

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Clinico-epidemiological profile & outcome of patients presenting with cerebral venous thrombosis to emergency department.

Am J Emerg Med

November 2024

Department Of Medicine, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India; Department Of Emergency medicine & Trauma, Jawaharlal Institute Of Postgraduate Medical Education & Research, Puducherry, India.

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