321 results match your criteria: "Bradley-Hasbro Children's Research Center[Affiliation]"

Reflective supervision (RS) has been viewed as best practice and is therefore incorporated-and often mandated-as a key feature of many relationship-based infant and early childhood serving programs. To promote the implementation of high-quality RS for infant and early childhood professionals, it is critical that a focus is placed on how infant and early childhood professionals are trained to build RS capacities. To this end, we describe Rhode Island, United States's journey developing, implementing, and iteratively adapting an RS professional development series.

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Objectives: To examine the extent to which asthma symptom concordance (ASC) or discordance (ASD) is associated with sleep outcomes in children with persistent asthma. Also, to investigate whether the association between ASC and sleep outcomes varies as a function of children's level of asthma control and severity.

Methods: A retrospective data analysis of Project NAPS (Nocturnal Asthma and Performance in School), an observational study which examined asthma and sleep outcomes in children with persistent asthma.

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Increased Rate of Unique Mitochondrial DNA Deletion Breakpoints in Young Adults With Early-Life Stress.

Biol Psychiatry Glob Open Sci

March 2025

Initiative on Stress, Trauma, and Resilience, Department of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, Rhode Island.

Background: Mounting evidence suggests that mitochondria respond to psychosocial stress. Recent studies suggest mitochondrial DNA (mtDNA) deletions may be increased in some psychiatric disorders, but no studies have examined early-life stress (ELS) and mtDNA deletions. In this study, we assessed mtDNA deletions in peripheral blood mononuclear cells of medically healthy young adults with and without ELS.

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The effects of experimental sleep disruption on daytime performance among children with asthma living in urban environments.

Sleep Health

January 2025

Bradley-Hasbro Children's Research Center, Hasbro Children's Hospital, Providence, Rhode Island, USA; Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA; Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.

Objectives: Children with asthma living in urban environments are at risk for disrupted sleep due to the presence of nocturnal asthma symptoms and urban stressors. Suboptimal sleep can affect children's daily functioning. The current study examined the effects of experimental sleep disruption on daytime performance in children with persistent asthma from urban backgrounds.

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Although prior studies have examined associations of personality traits with sleep, most have investigated self-reported sleep, been cross-sectional, and focused on younger and middle-aged adults. We investigated associations of personality with actigraphic sleep parameters and changes in sleep in 398 cognitively normal adults aged 40-95 years (M ± SD = 70.1 ± 12.

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Cannabis use disorder is common among young adults in psychiatric care, particularly those at risk for psychosis. Yet, interventions tailored to address this issue are limited. The goal of this qualitative study was to determine barriers and facilitators for reducing/quitting cannabis use, and to obtain end-user perspectives to inform a mobile app-based intervention.

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Objective: Insomnia, anxiety, and depression are common and co-morbid amongst college students. The mechanisms by which trait factors like intolerance of uncertainty and anxiety sensitivity connect to state anxiety and depression is unclear, but insomnia may mediate that relationship.

Participants: College students ( = 439) were recruited from national and local sources.

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Effortful Control, Parent-Child Relationships, and Behavior Problems among Preschool-Aged Children Experiencing Adversity.

J Child Fam Stud

February 2024

Initiative on Stress, Trauma, and Resilience (STAR Initiative), Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.

Young children who experience adversity are at increased risk for developing psychological difficulties across the lifespan. Among community samples, parent-child relationship dynamics interact with child effortful control to predict child behavior problems. The nature of these associations has not been examined among children who have experienced early childhood adversity and who may be particularly sensitive to familial effects on child development.

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Objective: Using a family network approach, we examined patterns of remembered parental rearing by both parents and associations with maternal and infant outcomes.

Background: Women's memories of how they were cared for by their own mothers in childhood are associated with important outcomes in the perinatal period. However, few studies assess women's recollections of caregiving by their fathers, despite fathers' influence on the larger family context and child adjustment.

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Article Synopsis
  • The study investigates how different patterns of childhood adversity (CA) affect the success of Trauma-Informed Care (TIC) for adolescents in residential treatment.
  • Using longitudinal data from 1,343 diverse youths, researchers identified five distinct CA patterns and assessed their impact on emotional and behavioral outcomes during treatment.
  • Results showed that while all groups improved emotionally, changes in conduct problems and behaviors like aggression and self-injury varied significantly by CA pattern, suggesting the need for more personalized support within TIC programs based on individual backgrounds.
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COBRE Center for Stress, Trauma, and Resilience (STAR COBRE): A Regional and National Hub for Transformative Research to Elucidate and Mitigate the Lasting Imprint of Early Stress and Trauma.

R I Med J (2013)

November 2024

COBRE Center for Stress, Trauma, and Resilience (STAR), The Miriam Hospital, Center for Behavioral and Preventive Medicine, The Miriam Hospital, Department of Psychiatry and Human Behavior, Brown University, Providence, RI.

Early adversity is a major contributor to psychiatric conditions and poor physical health that burden individuals and groups across Rhode Island, the United States, and globally. We established a Center of Biomedical Research Excellence (COBRE) for Stress, Trauma, and Resilience (STAR) at The Miriam Hospital to identify mechanisms linking early adversity and health, to curtail detrimental consequences of stress and trauma, and promote resilience. The STAR COBRE is a vibrant regional and national hub for transformative research to elucidate and mitigate the lasting imprint of stress and trauma across the lifespan.

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Objectives: To characterize representation and inclusion among Sleep Research Society members and examine associations between sociodemographic features and Sleep Research Society experiences.

Methods: The Sleep Research Society Taskforce for Diversity and Inclusion developed a web-based questionnaire in 2021, assessing membership data and Sleep Research Society experiences (self-initiated and society-initiated participation, feeling very welcomed, perceptions of inclusiveness, and diversity of viewpoints represented). Frequencies were calculated and adjusted Poisson regression models with robust variance were fit to estimate associations.

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The science of developmental psychopathology has made outstanding progress over the past 40 years in understanding adaptive and maladaptive developmental processes across the life span. Yet most of this work has been researcher driven with little involvement of community partners in the research process, limiting the potential public health significance of our work. To continue to advance the field we must move beyond the physical and conceptual walls of our research laboratories and into the real world.

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Article Synopsis
  • The study explored how early life adversity, specifically home threat, influences epigenetic age acceleration in adolescents through various sleep characteristics like duration, efficiency, and timing.
  • Researchers analyzed data from 861 participants at age 15, linking childhood home-threatening experiences to decreased sleep quality and patterns.
  • Results suggested that poor sleep mediated the connection between early home threat exposure and faster aging, highlighting the need for improved pediatric sleep health to mitigate the negative impact of early adversity.
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Considering chronotype to improve hypertension management.

EClinicalMedicine

September 2024

Institute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic.

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Objective: Despite a marked increase in the prevalence of pediatric IgE-mediated food allergy (FA) in recent decades, there is a dearth of age-appropriate management education and support tools for youth with FA. The purpose of this report is to detail our methods for intervention design and refinement of an interactive educational software program for school-aged children with FA.

Methods: Development of the "Friends, Family and Food Application (F3-App)" employed an iterative, user-centered design approach with input from children with FA, their caregivers, and other key experts.

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Research demonstrates the important role of genetic factors in attention-deficit/hyperactivity disorder (ADHD). DNA sequencing of families provides a powerful approach for identifying de novo (spontaneous) variants, leading to the discovery of hundreds of clinically informative risk genes for other childhood neurodevelopmental disorders. This approach has yet to be extensively leveraged in ADHD.

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Study Objectives: We examined whether sleep (i.e. quality, regularity, and duration) mediated associations between child maltreatment (CM) and depressive symptoms among emerging adults undergoing the major life transition of starting college.

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The COVID-19 pandemic resulted in significant changes in daily life, potentially impacting mental health and substance use behavior. Research on COVID-related changes in adolescent substance use have yielded mixed findings. The current cross-sectional chart review study compared rates of past-year substance use before and during COVID-19 among adolescent psychiatric inpatients, and investigated how motives for coping with COVID-19 changes were related to psychiatric acuity, and past-year substance use.

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There has been great interest in analyzing the potential of mindful parenting in promoting family well-being. Studies indicated that there is a lack of research on the predictive relationship between parenting practice and youth emotional and behavioral problems analyzed from a multi-informant perspective. This study evaluates the family-centered profiles of mothers and fathers' mindful parenting and negative parenting and youth problems associated with those profiles.

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During adolescence, youth increase in both independence and conflict with parents. Parents vary in how much they know about their adolescents' whereabouts and activities and how they acquire this information (i.e.

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Early childhood trauma has been linked to neurocognitive and emotional processing deficits in older children, yet much less is known about these associations in young children. Early childhood is an important developmental period in which to examine relations between trauma and executive functioning/emotion reactivity, given that these capacities are rapidly developing and are potential transdiagnostic factors implicated in the development of psychopathology. This cross-sectional study examined associations between cumulative trauma, interpersonal trauma, and components of executive functioning, episodic memory, and emotion reactivity, conceptualized using the RDoC framework and assessed with observational and performance-based measures, in a sample of 90 children (ages 4-7) admitted to a partial hospital program.

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Nutritional status has clinical relevance and is a target of guidance to parents of children with cystic fibrosis (CF). Growth is routinely monitored in CF clinics but there is no standardized way of assessing appetitive behaviors or parents' perceptions of their children's appetite. Greater understanding of these factors could improve clinical guidance regarding parent feeding behaviors.

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Parent-child relationship dynamics have been shown to predict socioemotional and behavioral outcomes for children, but little is known about how they may affect biological development. The aim of this study was to test if observational assessments of parent-child relationship dynamics (cohesion, enmeshment, and disengagement) were associated with three biological indices of early life adversity and downstream health risk: (1) methylation of the glucocorticoid receptor gene (), (2) telomere attrition, and (3) mitochondrial biogenesis, indexed by mitochondrial DNA copy number (mtDNAcn), all of which were measured in children's saliva. We tested hypotheses using a sample of 254 preschool-aged children ( age = 51.

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