1,043 results match your criteria: "Bourguiba University Hospital[Affiliation]"

Primary Ewing Sarcoma in the Sphenoidal Sinus: A Case Report.

Ear Nose Throat J

September 2024

ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.

Ewing's sarcoma (EWS) is a rare malignant bone tumor that primarily affects children and young adults. While it typically affects long bones, it can occur in the head and neck region, including the paranasal sinuses in rare cases. We present a challenging case of a 45-year-old female diagnosed with an EWS of the sphenoidal and the right nasal fossa.

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Invasive pulmonary aspergillosis in patients with acute leukemia.

Tunis Med

September 2024

Department of hematology University Hedi Chaker Hospital Faculty of Medecine Sfax, University of Sfax.

Introduction: Invasive pulmonary aspergillosis is a serious complication in hematology.

Aim: Describe the prevalence, diagnostic aspects, therapeutic modalities, and evolution of the IPA cases occurring in patients with acute leukemia.

Methods: Our study was retrospective including patients with acute leukemia who developed invasive pulmonary aspergillosis during the period January 2009 and December 2020 at the hematology department in south Tunisia.

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Tuberculosis is a rare but treatable infectious disease that continues to pose a significant health issue in regions with high prevalence. Its abdominopelvic localization can mimic advanced ovarian cancer, leading to diagnostic challenges. This report describes the case of a 33-year-old woman who was admitted to the gastroenterology unit with ascites, peritoneal thickening, and an ovarian mass on imaging.

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Key Guidelines for Responding to Reviewers.

F1000Res

September 2024

Hôpital Farhat HACHED, Laboratoire de recherche LR12SP09 «Insuffisance cardiaque», 4000 Sousse, Université de Sousse Faculté de Médecine de Sousse, Sousse, 4000, Tunisia.

Background: The process of preparing a scientific manuscript is intricate, encompassing several critical stages, including pre-writing, research development, drafting, peer review, editing, publication, dissemination, and access. Among these, the peer review process (PRP) stands out as a pivotal component requiring seamless collaboration among editors, reviewers, and authors. Reviewers play a crucial role in assessing the manuscript's quality and providing constructive feedback, which authors must adeptly navigate to enhance their work and meet journal standards.

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CIC variants and folinic acid-responsive seizures.

Mol Genet Metab

October 2024

Division of Neurology, Department of Pediatrics, Prince Sultan Military Medical City, Riyadh, Saudi Arabia. Electronic address:

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Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome characterized by insulin-like growth factor-2 (IGF-2) release, often associated with diverse tumor types. Gastrointestinal stromal tumors (GISTs), sarcomatous lesions of the gastrointestinal tract, are rarely associated with NICTH. We present a unique case of a 58-year-old patient diagnosed with a GIST exhibiting recurrent hypoglycemia suggestive of NICTH.

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Sea-fan retinal neovascularization associated with rickettsial retinitis: a case report.

BMC Ophthalmol

September 2024

Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, 1st June Street, Monastir, 5000, Tunisia.

Background: Rickettsial disease has been commonly associated with retinitis, retinal vasculitis, and optic nerve involvement, but the development of retinal neovascularization has been very rarely reported. We herein describe a case of rickettsial retinitis complicated with the development of sea-fan retinal neovascularization documented with multimodal imaging, including fundus photography, SS-OCT, fluorescein angiography, and SS-OCT angiography.

Case Presentation: A 26-year-old female with a history of fever one week earlier presented with sudden decreased vision in the left eye.

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Article Synopsis
  • - Wastewater genomic surveillance in Tunisia analyzed samples from six treatment plants to monitor SARS-CoV-2 and identify its variants from December 2021 to July 2022.
  • - The study found that viral RNA levels in wastewater correlated with local COVID-19 case reports and detected the Delta and Omicron variants, including the concerning BA.5 variant before it was officially recognized.
  • - Results indicated that wastewater treatment processes in Tunisia are not fully effective at eliminating SARS-CoV-2, as the virus was still present in treated effluents, highlighting a gap in public health monitoring.
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Burkitt's lymphoma (BL) is an aggressive B-cell lymphoma that occurs in children and adults. It is a chemosensitive lymphoma with very exceptional cases of late relapse. We report the case of a 32-year-old male, originally from a nonendemic area for BL, who was successfully treated for abdominal BL 20 years ago.

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Since the introduction of effective chemotherapy, the development of new diagnostic tools, and raising public awareness of the devastating health, social, and economic consequences of tuberculosis (TB), the frequency of this disease has decreased. Pulmonary TB is the most common form of the disease, but TB bacilli can spread to other organs including lymph nodes, and the oral cavity especially the tongue with very unusual features. Oral lesions, although rare, are very important for early diagnosis and interception of primary TB.

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Introduction: postoperative sore throat (POST) is a common complication after general anesthesia with endotracheal intubation caused by tracheal mucosal injury. Multiple techniques prevent postoperative sore throat (POST). Our study aimed to compare two techniques: intravenous and intracuff lidocaine versus placebo to prevent postoperative sore throat after general anesthesia with orotracheal intubation.

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Sex-related differences in toxic manifestations induced by Bothrops atrox venom in mice.

Toxicon

October 2024

. Intensive Care Unit, Cayenne General Hospital, French Guiana; . Tropical Biome and Immunopathology CNRS UMR-9017, Inserm U 1019, Université de Guyane, French Guiana; . Laboratory of Medicinal and Environment Chemistry, Higher Institute of Biotechnology, University of Sfax, PB 261, Sfax, 3000, Tunisia.

Article Synopsis
  • Lancehead snakes (Bothrops) cause 90% of snakebites in Latin America, prompting a study on the effects of B. atrox venom in male and female mice.
  • The research found that male mice exhibited a lower lethal dose (LD) and more severe physical symptoms from the venom compared to females, particularly via the intraperitoneal injection route.
  • Hematological changes, including a significant drop in total leukocyte levels, were more pronounced in males, indicating a greater susceptibility to B. atrox venom and highlighting the need to consider sex differences in venom studies.
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Sleep Habits and Disturbances Among Tunisian Adults: A Cross-Sectional Online Survey [Response to Letter].

Nat Sci Sleep

August 2024

Department of Respiratory and Sleep Medicine, Hedi Chaker University Hospital of Sfax, Faculty of Medicine of Sfax, University of Sfax, Sfax, Tunisia.

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Article Synopsis
  • * A case involving a 16-year-old showed elevated inflammatory markers and imaging revealed significant bone damage and infections in the pubic area.
  • * The patient responded well to a 2-month antibiotic treatment, highlighting the importance of early diagnosis and intervention to improve recovery outcomes.
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Article Synopsis
  • Moebius syndrome (MS) is a rare condition that causes facial paralysis, affecting emotional expression, and can be addressed through a palliative surgery called lengthening temporalis myoplasty (LTM).
  • A case study of a 29-year-old woman demonstrated that after LTM surgery, a structured 12-month rehabilitation program led to significant improvement, enabling her to achieve a spontaneous and symmetrical smile.
  • The study highlights that combining surgery with comprehensive rehabilitation, including speech therapy and psychological support, is essential for lasting smile restoration in MS patients.
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Objective: Renal colic (RC) is a common urologic emergency often leading to significant pain and recurrent hospital visits. This study aimed to compare the efficacy and safety of piroxicam versus paracetamol in preventing pain recurrence and hospital readmission in patients treated for RC and discharged from the emergency department (ED).

Methods: A prospective, randomized, single-blind trial was conducted in four EDs.

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Crusted plaques on the face.

Int J Dermatol

December 2024

Dermatology Department, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.

Article Synopsis
  • - Facial neutrophilic dermatosis is a rare skin condition recently identified, characterized by crusty lesions resembling pyoderma gangrenosum, but with limited involvement of the facial area.
  • - There is some debate among experts regarding its classification, with some considering it a variant of Sweet's syndrome and others treating it as a distinct entity.
  • - Recent cases, including the one discussed, have noted potential links between facial neutrophilic dermatosis and conditions like ulcerative colitis, suggesting diverse clinical presentations.
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Isolated diaphragmatic hydatid cyst: a rare entity in the paediatric population.

J Surg Case Rep

August 2024

Surgical Research Section, Department of Surgery, Hamad Medical Corporation, Doha 2001, Qatar.

Isolated primary diaphragmatic hydatid disease (HD) occurs in approximately 1% of adult cases. However, this unique presentation of a pediatric diaphragmatic cystic mass has not been previously described in the literature. This study reports a rare case of a 12-year-old girl who was diagnosed with a diaphragmatic hydatid cyst.

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Congenital facial nerve (FN) malformations are uncommon. Our aim is to determine the clinical and radiological features of FN malformations along with the associated cochlear and vestibular malformations. We conducted a retrospective study including children with a profound sensorineural hearing loss who were candidates for cochlear implantation.

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Introduction: Facial gunshot wounds have devastating functional and aesthetic consequences for the patient. If associated with penetrating craniocerebral injuries, the prognosis is rather compromised even with appropriate medical and surgical treatment. Chop-off injuries with penetrating wounds constitute a challenging situation for the facial reconstructive surgeon in facial trauma.

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[Not Available].

Tunis Med

August 2024

Parasitology - Medical and Molecular Mycology Research Laboratory (LR12ES08), Faculty of Pharmacy of Monastir, University of Monastir, Tunisia.

Article Synopsis
  • Microscopy is the standard method for diagnosing malaria, but its accuracy can vary based on the experience of the examiner and the level of parasites present, making molecular biology a valuable alternative.
  • A study was conducted from September 2020 to April 2021 in the Monastir region to assess the effectiveness of three detection methods for malaria in students, revealing that nested PCR identified cases missed by microscopy.
  • The findings suggest that nested PCR is more sensitive for detecting low levels of malaria parasites, highlighting the need to incorporate molecular biology techniques into malaria screening for better identification of imported cases.
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12-week melatonin supplementation improved dynamic postural stability and walking performance in persons living with multiple sclerosis: A randomized controlled trial.

Behav Brain Res

January 2025

LINP2, UFR STAPS, University of Paris Nanterre, Nanterre, France; Research Laboratory, Molecular bases of Human Pathology, LR19ES13, Faculty of medicine of Sfax, University of Sfax, Tunisia.

Article Synopsis
  • Persons with multiple sclerosis (PwMS) often face issues like sleep disturbances, fatigue, and pain, which can affect their balance and walking, potentially increasing fall risk.
  • This study investigated the long-term effects of chronic melatonin supplementation on PwMS, comparing a melatonin group with a placebo group over 12 weeks.
  • Results showed improvements in dynamic postural stability, walking performance, sleep quality, fatigue perception, and neuropathic pain in the melatonin group, suggesting it could be beneficial for managing symptoms in PwMS.
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Introduction: Identifying heart failure (HF) in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) can be challenging. Lung ultrasound sonography (LUS) B-lines quantification has recently gained a large place in the diagnosis of HF, but its diagnostic performance in AECOPD remains poorly studied.

Purpose: This study aimed to assess the contribution of LUS B-lines score (LUS score) in the diagnosis of HF in AECOPD patients.

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Lung imaging techniques are crucial for managing ventilated patients in pediatric intensive care units (PICUs). Bedside chest x-ray has limitations such as low sensitivity and radiation exposure risks. Recently, lung ultrasound has emerged as a promising technology offering advantages such as real-time monitoring and radiation-free imaging.

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The mastoid bone, situated at the base of the skull and characterized by its compact structure in the petrous portion, being among the slowest-growing bones, has gained recognition as a valuable anthropological tool for sex determination. Thus, we have proposed to assess the reliability of the mastoid process in sex determination in a Tunisian population using CT-scan analysis. A cross-sectional study was conducted.

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