10 results match your criteria: "Bordeaux University Pellegrin Hospital[Affiliation]"

Article Synopsis
  • This study analyzed data from multiple centers to explore how machine learning can help in predicting treatment strategies (surgery vs. conservative) for patients with adult spine deformity (ASD).
  • It found that patients whose initial treatment approach matched the machine learning predictions were more likely to reach meaningful clinical improvement, measured by the Minimum Clinically Important Difference (MCID) in various health indices.
  • The results indicated that different patient clusters (based on conditions like scoliosis and sagittal imbalance) showed varying success rates in achieving MCID, emphasizing the importance of accurate treatment predictions in improving patient outcomes.
View Article and Find Full Text PDF

Purpose: The Minimal Clinically Important Difference (MCID) is crucial to evaluate management outcomes, but different thresholds have been obtained in different works. Part of this variability is due to measurement error and influence of the database, both essential for calculating the MCID. The aim of this study was to introduce the association of the ROC method in the anchor-based MCID calculation for ODI, SRS-22r, and SF-36, to objectively set the threshold for the anchor-based MCID in an adult spine deformity (ASD) population.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the relationship between rod curvature and postoperative outcomes, aiming to provide a validated method for measuring rod curvature using X-rays and a regression algorithm to minimize manual errors.
  • Data from 20 adolescent and 35 adult patients with spine deformities were analyzed, involving the marking of rod points on X-rays and applying a polynomial regression to determine rod curvature equations.
  • Results show high reliability of the new measurement method, with intra-observer intraclass correlation coefficients exceeding 0.85 and excellent inter-observer reliability (0.98) particularly noted in the adolescent idiopathic scoliosis/Scheuermann kyphosis group.
View Article and Find Full Text PDF

Study Design: Retrospective analysis of prospectively collected data.

Objective: To identify the best definition of primary anteverted pelvis in the setting of adult spine deformity (ASD), and to investigate whether this is a pathologic setting that requires surgical correction.

Summary Of Background Data: While pelvic retroversion has been thoroughly investigated, pelvic anteversion (AP) is a far lesser discussed topic.

View Article and Find Full Text PDF
Article Synopsis
  • Coronal balance plays a crucial role in the surgical success of adult spinal deformity (ASD), and the Obeid coronal malalignment (O-CM) classification aims to enhance surgical outcomes by improving alignment.
  • At a 2-year follow-up, patients whose surgeries adhered to the O-CM guidelines experienced a lower rate of mechanical complications (40% vs. 60%) and significant improvements in patient-reported outcome scores.
  • A post-surgery coronal alignment correction to less than 20 mm was linked to better functional outcomes and a 3.5 times higher likelihood of achieving essential clinical improvements in the SRS-22 score.
View Article and Find Full Text PDF

Purpose: Achieving an adequate level of patient's satisfaction with results is one of the goals of adult spinal deformity (ASD) surgery. However, it is unclear whether the same factors affect satisfaction in all patient populations. Patients' age influences the postoperative course and prevalence of complications after ASD surgery.

View Article and Find Full Text PDF
Article Synopsis
  • Coronal malalignment (CM) in adult spinal deformity (ASD) can lead to pain and functional issues, but it has been less studied compared to sagittal malalignment; the study aimed to establish a reliable classification system for CM among spine surgeons.
  • Fifteen readers assessed 28 CM cases using various radiographs, and intra-rater reliability scores were high, indicating strong consistency among readers; inter-rater reliability varied, showing some readers disagreed more than others.
  • The Obeid-CM classification demonstrated good reliability for categorizing CM, suggesting that surgeons should evaluate both sagittal and coronal alignment to enhance surgical decisions, even though side bending radiographs only slightly helped in understanding specific
View Article and Find Full Text PDF

Purpose: Preoperative patient self-image (SI) in adult spinal deformity (ASD) is the most relevant factor for surgical decision-making. Postoperative SI has an important role in a patient's satisfaction with surgery. However, few studies are available to describe these variables.

View Article and Find Full Text PDF

Objective: Achieving high patient satisfaction with management is often one of the goals after adult spinal deformity (ASD) surgery. However, literature on associated factors and their correlations with patient satisfaction is limited. The aim of this study was to determine the clinical and radiographic factors independently correlated with patient satisfaction in terms of management at 2 years after surgery.

View Article and Find Full Text PDF

Neurocognitive profiles in MSUD school-age patients.

J Inherit Metab Dis

May 2017

Reference Centre for Inborn Errors of Metabolism, Robert Debré University Hospital, APHP, 48 boulevard Sérurier, 75019, Paris, France.

Maple syrup urine disease (MSUD), an inborn error of amino acids catabolism is characterized by accumulation of branched chain amino acids (BCAAs) leucine, isoleucine, valine and their corresponding alpha-ketoacids. Impact on the cognitive development has been reported historically, with developmental delays of varying degree. Currently, earlier diagnosis and improved management allow a better neurodevelopment, without requirement of special education.

View Article and Find Full Text PDF