Generating Real-World Evidence From the Excellence Network in Rheumatology.

Purpose: The Excellence Network in RheumatoloGY (ENRGY) was founded in 2021 and encompasses data from more than 700 private practice rheumatology providers throughout the United States, forming a practice-based research network (PBRN).

Methods: Electronic health record (EHR) data from participating practices are aggregated, including structured data (e.g.

Disciplinary Thinking for the Scholarship of Nursing Research.

The author critiques the current American Association of Colleges of Nursing definition of nursing scholarship for its lack of emphasis on building discipline-specific knowledge. The author defines nursing scholarship as scholarly activities and formal investigations designed to generate, synthesize, translate, apply, and disseminate discipline-specific knowledge that advances nursing's societal commitments and responsibilities in promoting human health, human betterment, and wellbecoming. Nursing scholarship guided by disciplinary thinking consists of scholarship that is (a) informed by nursing philosophy; (b) framed within nursing's metaparadigm concepts; (c) situated within a nursing paradigm; (d) conceptualized within a nursing conceptual framework or nursing midrange theory; and (e) focused on, depending on one's paradigmatic and theoretical perspective, developing and testing concepts in nursing classification systems.

Electro-deformation spectroscopy: A unified method for simultaneous electrical and mechanical characterization of single cells.

The intrinsic electrical and mechanical properties of cells are not only valuable biophysical markers reflective of physiological conditions but also play important roles in the development and progression of human diseases. Existing single-cell techniques are restricted to assessing either mechanical or electrical properties. We introduce the development of electro-deformation spectroscopy (EDS), namely the frequency-dependent electro-deformation, as a new method for simultaneous electrical and mechanical characterization of individual cells in suspension.

Implementing INTERACT in Veterans Health Administration Community Living Centers: A pragmatic randomized trial.

Background: Hospital transfers from VA Community Living Centers (CLCs) are common. The objective of this study was to evaluate the effect of introducing the Intervention to Reduce Acute Care Transfers (INTERACT) program into VA CLCs.

Methods: Cluster randomized trial involving 16 pair-matched VA CLCs.

Narratives in European debate concerning new genomic techniques.

Given the complexity of agricultural problems, it is essential to develop acceptable solutions for various stakeholders with diverse knowledge, viewpoints, and preferences. However, European public opinion has become highly polarized, making constructive discussions on these issues difficult. We present the results of the narrative analysis of media debate on new genomic techniques.

A Qualitative Study of Postpartum Women's Lived Experiences During COVID-19.

Introduction: According to the Centers for Disease Control and Prevention, the state of Florida became the epicenter of the COVID-19 delta variant during the summer of 2021. There is limited knowledge on how the pandemic impacted postpartum women's lived experiences in the United States. The purpose of the study was to explore the lived experiences of postpartum women living in South Florida during the COVID-19 pandemic and their responses.

A Randomized Crossover Pilot Trial on the Influence of a Daily Mindfulness Yoga Practice on Menstrual Cycle Symptoms, Measures of Well-Being, and Training Perception in Athletic Women.

The menstrual cycle (MC) is a series of hormonal fluctuations that occur approximately every 22-35 days in reproductive-age females, often resulting in a range of physical and psychological symptoms at different points of the cycle. MC symptoms range from mild discomfort to debilitating effects. One intervention that may be able to address these symptoms is yoga, a mind-body practice that incorporates physical postures with breathwork to foster a mindful connection to the body.

International experts consensus on optimal central vascular access device selection and management for patients with cancer.

Background: In patients with cancer, the choice of an appropriate venous access device is crucial for effective treatment, minimizing complications, and reducing healthcare costs. Key management decisions, such as the timing of device removal post-therapy, can impact clinical outcomes. As current international guidelines lack specific directives for these issues, a global consensus of experts, representing different countries, was deemed appropriate.

Exploring the dosimetric impact of systematic and random setup uncertainties in robust optimization of head and neck IMPT plans.

Purpose: This study aims to compare the dosimetric impact of incorporating systematic and random setup uncertainties in the robust optimization of head and neck cancer (HNC) Intensity Modulated Proton Therapy (IMPT) plans.

Methods: Bilateral HNC patients (n = 10) previously treated with conventional photon therapy at our institution were included. Both systematic and random setup uncertainties were incorporated into the robust optimization process of IMPT planning.

Y chromosome introgression between deeply divergent primate species.

Hybridization and introgression are widespread in nature, with important implications for adaptation and speciation. Since heterogametic hybrids often have lower fitness than homogametic individuals, a phenomenon known as Haldane's rule, loci inherited strictly through the heterogametic sex rarely introgress. We focus on the Y-chromosomal history of guenons, African primates that hybridized extensively in the past.

Volumetric Artificial Intelligence Analysis of Prerupture and Postrupture Cerebral Aneurysms: Assessment of Morphologic Change.

Background: Cerebral aneurysm rupture is a major cause of potential years of life lost. Research on rupture risk has often compared unruptured and ruptured aneurysms, with the implicit assumption that the rupture event does not significantly change aneurysm morphology. However, aneurysm morphology is charged by rupture, although precisely how remains a matter of debate.

Are we training the trainers? Leadership educator preparation in student affairs programs.

Recently, leadership education researchers and practitioners have raised significant concerns about the gap between the expectations of, and professional training for, leadership educators in student affairs. These professionals are frequently required to facilitate leadership learning, especially in co-curricular training spaces for student leaders. However, they are often not adequately prepared or resourced by their professional development to deliver these training experiences.

Exploring facilitators and barriers to daily chlorhexidine gluconate bathing in adult patients undergoing hematopoietic stem cell transplantation.

Unlabelled: Hematopoietic cell transplantation (HCT) is a promising treatment for hematologic malignancies, but intensive conditioning leads to immunosuppression and susceptibility to healthcare-associated infections (HAI). Despite standard prevention measures, bloodstream infections (BSI) impact a significant percentage of immunocompromised HCT patients. Incidence of BSI can be mitigated by chlorhexidine gluconate (CHG) bathing-an underutilized infection-prevention strategy.

Benzodiazepine rescue medication administration for seizure clusters: Real-world retrospective outcomes.

Objective: Benzodiazepine rescue medications are established as therapy for acute termination of seizure clusters. A post-hoc analysis of a clinical trial of seizure cluster treatment with diazepam nasal spray found a potential longer-term impact over a year of treatment. In this retrospective analysis, we tested the hypothesis that benzodiazepine-treated seizure clusters are associated with prolonged time to the next seizure cluster compared with untreated seizure clusters in a patient-reported real-world database.

Diagnosis and Management of Orthopaedic Conditions Associated With Hereditary Sensory Autonomic Neuropathies.

Hereditary sensory and autonomic neuropathies (HSANs) encompass a diverse group of inherited neuropathies characterized by notable sensory and autonomic involvement that affects musculoskeletal structures and systemic function. There are 8 recognized types of HSAN. The orthopaedic manifestations of HSAN are complex and diverse, including spinal deformity, Charcot arthropathy, osteomyelitis, fractures, osteonecrosis, osteoporosis, and skeletal deformities.

Reframing the environment domain of the nursing metaparadigm: Exploring space, place, and technology.

Metaparadigms differentiate disciplines in terms of how each discipline develops its knowledge and its scholarship. Four domains comprise the nursing metaparadigm: environment, person, health, and nursing Of these domains, the environment domain is the least identified. Relating this domain to the broader substantive meaning of the geographical-landscape setting of nursing encounters requires further explanation Through a discursive process, the article positions "space and place" by referencing the nursing environment.

Immediate Treatment of Seizure Clusters: A Conceptual Roadmap to Expedited Seizure Management.

Some patients with epilepsy continue to have seizures despite daily treatment with antiseizure medications. This includes seizure clusters (also known as acute repetitive seizures), which are an increase in seizure frequency that is different from the usual seizure pattern for that patient. In the literature, the term "rescue" is used for pharmacologic treatment for seizure clusters, but clarity regarding timing or whether a caregiver or patient should wait until a moment of life-threatening urgency before administering the medication is lacking.

Radiosurgery for Hypothalamic Gliomas: A Case Report and Clinical Guidelines Form a Neurosurgical Center of Excellence.

Hypothalamic gliomas, though rare, present significant challenges in neuro-oncology due to their critical location and high morbidity risk. Pilocytic astrocytoma is the most common subtype, requiring a delicate balance between tumor control and preservation of neurological function. This study explores radiosurgery as a viable treatment option for hypothalamic gliomas, with a focus on low-grade lesions.

Advances in Cardiovascular Wearable Devices.

Cardiovascular diseases are a leading cause of death worldwide. They mainly include coronary artery disease, rheumatic heart disease, andcerebrovascular disease, and. Cardiovascular diseases can be better managed and diagnosed using wearable devices.

Trends in Childhood Behavioral, Mental, and Developmental Problems (2019-2022) Using the National Survey of Children's Health.

Background: This study examines nationwide prevalence of US childhood behavioral, mental, and developmental problems in the 6-11 age group category between 2019 and 2022, and several key metrics related to caregiver social determinants of health.

Methods: We used NSCH data for 6-11-year-old children for the years 2019-2022. Summary statistics for the selected sample were generated and binary logistic regressions were conducted for each severity level binary variable for each study year with caregiver mental or emotional health as a covariate.

Cardiac Papillary Fibroelastoma and Cerebrovascular Events: A Systematic Review.

Background: Cardiac papillary fibroelastomas (CPFs) are benign endocardial tumours with embolic potential. This article is a systematic review to identify the clinical profile, diagnosis, tumour characteristics, and treatment modalities in patients with CPF presenting with stroke or transient ischemic attack (TIA).

Methods: This systematic review was conducted using the PubMed and Embase databases, including case reports and/or series and observational studies (for a search period of up until April 2022).