Visual and Clinical Outcome of Macular Edema Complicating Pediatric Noninfectious Uveitis.

Purpose: To investigate the clinical course and visual outcome of macular edema (ME) in pediatric patients with chronic noninfectious uveitis.

Design: Retrospective case series.

Methods: The databases of the uveitis clinics of 4 tertiary medical centers in Israel and the UK were searched for all children treated for uveitic ME in the years 2005-2015.

The effects of crossing ethnic boundaries on the autonomic nervous system in Muslim and Jewish young women in Israel.

Exposure to alien inter-group environments can differently effect ethnic groups' autonomous nervous system, measured by heart rate variability (HRV). Our aim was to evaluate the effect of crossing alien ethnic boundaries on heart rate variability in three selected types of environments. In a field experiment study, we test responses of 72 Muslim and Jewish women to exposure to alien ethnic environments.

What Is the Color of Your Lymph Node?

We describe a case of tattoo ink in an axillary lymph node, which was observed during an axillary dissection and mastectomy surgery. It is important to be aware of this phenomenon and correctly identify it at the time of surgery, as a misdiagnosis can have serious consequences.

A comparison of the effects of selected mono-ethnic urban environments on the autonomic functions of Muslim and Jewish women in Israel.

Few previous studies evaluated ethnic differences in the effects of urban environments on the autonomic balance in intra-ethnic environments and the mediation effects of environmental exposures (air pollution, noise, and thermal load). In a field experimental study, we exposed 48 Muslim and 24 Jewish women to park, town center, and residential street in Israeli mono-ethnic small towns. Heart rate variability (HRV), noise, thermal load, and carbon monoxide (CO) were measured by portable devices while visiting the environments and were analyzed using mixed models.

Characteristics and behaviours of formal versus informal nurse champions and their relationship to innovation success.

Aims: To identify the sociodemographic attributes, project characteristics and champion strategies that differentiate formal from informal nursing champions, and to test their success in terms of project spread and novelty.

Background: Champions spread innovation in healthcare organizations. Empirical research has not explored the differences between formal and informal champions in terms of their antecedents and success.

Cognitive functioning of female nurses during the night shift: The impact of age, clock time, time awake and subjective sleepiness.

Decline in cognitive functioning in the workplace is a major concern for health care systems. Understanding factors associated with nighttime functioning is imperative for instituting organizational risk management policies and developing personalized countermeasures. The present study aims to identify individual factors associated with cognitive functioning during the night shift of hospital nurses working on irregular rotating-shift schedules.

Single-Nucleotide Polymorphisms in IL23R-IL12RB2 (rs1495965) Are Highly Prevalent in Patients with Behcet's Uveitis and Vary Between Populations.

: To test the frequency of single-nucleotide polymorphisms in the genes in patients with Behcet's uveitis. : Blood samples were collected from 89 Israeli and Turkish patients, and from healthy control subjects of different origins. Genomic DNA was extracted from peripheral blood leukocytes and genotyped.

Improved Patency of ePTFE Grafts as a Hemodialysis Access Site by Seeding Autologous Endothelial Cells Expressing Fibulin-5 and VEGF.

Small caliber synthetic vascular grafts used for dialysis access sites have high failure rates due to neointima formation and thrombosis. Seeding synthetic grafts with endothelial cells (ECs) provides a biocompatible surface that may prevent graft failure. We tested the use of ePTFE grafts seeded with autologous ECs expressing fibulin-5 and vascular endothelial growth factor (VEGF), as a dialysis access site in a porcine model.

Estrogen receptor and laminin genetic polymorphism among women with pelvic organ prolapse.

Objective: Laminin is a connective tissue component. The LAMC1 gene encodes for gamma-1 chain of laminin, which is associated with familial clustering of POP. The ERα gene which encodes for cellular estrogen receptor has also been associated with POP.

Who is sleepier on the night shift? The influence of bio-psycho-social factors on subjective sleepiness of female nurses during the night shift.

Sleepiness is a common complaint during the night shift and may impair performance. The current study aims to identify bio-psycho-social factors associated with subjective sleepiness during the night shift. Ninety-two female nurses working rotating shifts completed a sociodemographic questionnaire, the Munich ChronoType Questionaire for shift workers, the Pittsburg Sleep Quality Index, and the Pre-sleep Arousal Scale.

Low levels of the immunoregulator Semaphorin 4D (CD100) in sera of HIV patients.

Introduction: Semaphorin-4D (CD100), generated by CD4/CD8 T-cells and its receptor on B cells - CD72, play a role in immune regulation. Both have soluble forms - sCD100/sCD72.

Methods: sCD100 and sCD72 levels were determined by ELISA (MyBioSource, USA).

Anti-BLyS Treatment of 36 Israeli Systemic Lupus Erythematosus Patients.

Background: Anti-BLyS treatment with the human belimumab monoclonal antibody was shown to be a safe and effective therapeutic modality in lupus patients with active disease (i.e., without significant neurological/renal involvement) despite standard treatment.

Nonpainful remote electrical stimulation alleviates episodic migraine pain.

Objective: To evaluate the efficacy of remote nonpainful electrical upper arm skin stimulation in reducing migraine attack pain.

Methods: This is a prospective, double-blinded, randomized, crossover, sham-controlled trial. Migraineurs applied skin electrodes to the upper arm soon after attack onset for 20 minutes, at various pulse widths, and refrained from medications for 2 hours.

Somatic, psychological, and sexual triggers for overactive bladder syndrome in women.

Aims: Patients with overactive bladder (OAB) often describe somatic, psychological, and sexual triggers for their symptoms. The aim of this study was to characterize these triggers and assess their impact on patients' symptoms and quality of life (QoL).

Methods: Patients who visited our urogynecologic clinic between August 2015 and March 2016 and diagnosed with OAB syndrome were asked to fill a questionnaire comprising 34 statements regarding SOmatic, Psychological, and Sexual Triggers for OAB (SOPSETO).

Sequence variation in results in a novel form of cardio-cutaneous syndrome.

Dilated cardiomyopathy (DCM) is a life-threatening disorder whose genetic basis is heterogeneous and mostly unknown. Five Arab Christian infants, aged 4-30 months from four families, were diagnosed with DCM associated with mild skin, teeth, and hair abnormalities. All passed away before age 3.

Intraspinal hypotension syndrome presents as transient quadriplegia.

Intracranial hypotension can be a complication of epidural anaesthesia. Pure clinical spinal hypotension manifesting as acute transient quadriplegia following epidural anaesthesia is a severe, life-threatening complication that have not been described before. This complication can be solved with an epidural blood patch; thus, it should be familiar to doctors across all specialities.

Development and psychometric testing of a measure of older adult patients' attitudes towards mobility during hospitalization (ATM-H).

This paper describes the development and psychometric testing of a questionnaire evaluating attitudes towards mobility during hospitalization of older adults, an understudied phenomenon that lacks a valid and reliable measure. An instrument development procedure, followed by an empirical study, was conducted between December 2013 and June 2014. Instrument development included item generation and analysis of content validity, which was established by six experts.

The relationship between ambient carbon monoxide and heart rate variability-a systematic world review-2015.

The objective of this report is to systematically review the literature pertaining to the evidence of the relationship between environmental carbon monoxide (CO) and heart rate variability (HRV). For this purpose, reports published in English scientific journals were critically reviewed by the authors employing PRISMA guidelines. Fifteen studies performed in China, Finland, Israel, Mexico, Taiwan, and the USA were identified as eligible to be included in the review.

Thromboembolic events in patients with severe inherited fibrinogen deficiency.

Inherited afibrinogenemia and hypofibrinogenemia are rare bleeding disorders characterized by markedly reduced levels of fibrinogen in blood. Thrombotic complications in these disorders have been rarely described. We performed a multicenter retrospective study and reviewed the occurrence of thrombotic complications among patients with inherited fibrinogen deficiency.

Darier disease in Israel: combined evaluation of genetic and neuropsychiatric aspects.

Background: Darier disease (DD) is a rare genodermatosis caused by heterozygous mutations in the ATP2A2 gene. It has been associated with neuropsychiatric manifestations.

Objectives: To investigate the genetic basis of Israeli patients with DD, and its association with the neuropsychiatric phenotype.

Vaginal adhesions after transvaginal pelvic reconstructive surgeries: prevalence and clinical implications.

Introduction And Hypothesis: Our aim was to assess the prevalence of vaginal adhesions after transvaginal pelvic reconstructive surgeries and evaluate relevant risk factors and impact on surgical outcome and sexual function.

Methods: This was a retrospective study examining medical records of all patients undergoing transvaginal pelvic reconstructive surgeries for pelvic organ prolapse (POP) at our institution between January 2006 and December 2007.

Results: One hundred and ninety -nine women were included in the study, of whom 165 had a comprehensive pre- and postoperative follow-up assessment and were available for final analysis.