4 results match your criteria: "Biwako-Gakuen Medical and Welfare Center of Yasu[Affiliation]"
Cardiometabolic Effects of Antipsychotics in Challenging Behavior and Neuropsychiatric Symptoms in Patients With Intellectual Disability.
Cureus
November 2023
Department of Pediatrics, Biwako-Gakuen Medical and Welfare Center of Yasu, Yasu, JPN.
Introduction Despite the well-established association between antipsychotics and metabolic adverse effects in psychiatric disorders, the variable influence of long-term and off-label antipsychotic medication on behavioral disorders has not been investigated in detail. Objective To clarify the impact of antipsychotic use on challenging behavior (CB) and neuropsychiatric symptoms (NPS), we evaluated the clinical findings and cardiometabolic effects in individuals with intellectual disability (ID) hospitalized in our residential facility for profoundly disabled patients. Patients and methods A total of 130 individuals hospitalized in our residential facility were retrospectively investigated and divided into two groups - individuals with and without CB and NPS.
View Article and Find Full Text PDFSelf-injury as a predominant challenging behavior in epilepsy: A study in a residential facility for profoundly disabled patients.
Res Dev Disabil
January 2022
Department of Pediatrics, Biwako-Gakuen Medical and Welfare Center of Yasu, 978-2 Kitazakura, Yasu, 520-2321, Japan; Department of Pediatrics, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, 520-2192, Japan. Electronic address:
Background: The association between challenging behavior (CB) and epilepsy in people with intellectual disability (ID) remains largely controversial.
Aim: To clarify the correlation between CB and epilepsy, we investigated the clinical characteristics of CB in both people with and without epilepsy among individuals with ID hospitalized in our residential facility.
Methods And Procedures: A total of 63 individuals with CB was retrospectively investigated using the Behavior Problems Inventory, and the following items were collected from the medical records: sex, age, hospitalization period, etiology and risk factors, level of ID, type of CB, administration of psychotropic drugs, presence or absence of epilepsy and clinical features of epilepsy.
Progression of motor disability in cerebral palsy: The role of concomitant epilepsy.
Seizure
August 2020
Department of Orthopedics, Biwako-Gakuen Medical and Welfare Center of Yasu, 978-2 Kitazakura, Yasu, 520-2321, Japan.
Purpose: The aim of this study is to investigate the clinical characteristics of epilepsy affecting the progression of motor disabilities in cerebral palsy (CP).
Methods: CP patients were retrospectively followed for 15 years from January 2005 to January 2020, and the following items were collected from the medical records: sex, age, etiology, and the clinical features of epilepsy. All patients were divided into two groups of unchanging CP and worsening CP based on whether or not they showed progression of motor disabilities during 15 years' hospitalization, respectively.
Interneuron dysfunction in epilepsy: An experimental approach using immature brain insults to induce neuronal migration disorders.
Epilepsy Res
October 2019
Department of Pediatrics, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, 520-2192, Japan.
Article Synopsis
- * A decrease or damage to GABAergic interneurons may contribute to neural circuit problems associated with epilepsy and repeated seizures.
- * In studies using animal models, it was found that brain damage during development disrupts normal interneuron processes like production, migration, and organization, suggesting a strong connection between interneuron issues and epilepsy.