The 2023 fatal dengue outbreak in Bangladesh highlights a paradigm shift of geographical distribution of cases.

In 2023, Bangladesh experienced its largest and deadliest outbreak of the Dengue virus (DENV), reporting the highest-ever recorded annual cases and deaths. Historically, most of the cases were recorded in the capital city, Dhaka. We aimed to characterize the geographical transmission of DENV in Bangladesh.

External validation of AI-based scoring systems in the ICU: a systematic review and meta-analysis.

Background: Machine learning (ML) is increasingly used to predict clinical deterioration in intensive care unit (ICU) patients through scoring systems. Although promising, such algorithms often overfit their training cohort and perform worse at new hospitals. Thus, external validation is a critical - but frequently overlooked - step to establish the reliability of predicted risk scores to translate them into clinical practice.

The Development, Delivery, Content, and Impact of Nutrition Education in Prisons: A Systematic Review.

People in prison are at an increased risk of long-term conditions that have been associated with poor nutrition intake, low levels of physical activity, and obesity. We aim to identify the necessary components of nutrition education to impact the health and health behaviors of people in prison. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines informed the structure of this article.

Testing the Proteus Effect in Autistic and Neurotypical Participants.

This study examined the Proteus effect in autistic and neurotypical participants via the video game, The Sims. Thirty-two participants (16 autistic, 16 neurotypical) participated in a free-play session of The Sims, playing as either an attractive or unattractive avatar. In line with predictions, participants who had played as the attractive avatar negotiated for a significantly larger share of a fictional pot of money during a post-play economic game.

The effects of exercise on neuromuscular function in people with chronic neck pain: A systematic review and meta-analysis.

Background: Differences in cervical neuromuscular function are commonly observed between people with and without chronic neck pain. Exercise may improve cervical neuromuscular function of people with neck pain although the evidence for this has not been systematically reviewed.

Objective: To systematically review the existing evidence on the effect of exercises targeting the neck muscles on neuromuscular function in people with chronic non-specific neck pain.

ENVIRONMENTAL MEDIATION OF COLISTIN RESISTANCE IN THE AFRICAN CONTEXT. A SYSTEMATIC SCOPING REVIEW.

Introduction: The prevalence of antimicrobial resistance (AMR) among Gram-negative bacteria is a major global health concern. Resistance to last-resort antibiotics like colistin is particularly alarming. This study reviews how environmental factors have contributed to colistin resistance in the African context, where reports of colistin-resistant Gram-negative organisms are emerging.

Enhancing ransomware defense: deep learning-based detection and family-wise classification of evolving threats.

Ransomware is a type of malware that locks access to or encrypts its victim's files for a ransom to be paid to get back locked or encrypted data. With the invention of obfuscation techniques, it became difficult to detect its new variants. Identifying the exact malware category and family can help to prepare for possible attacks.

The habitus and field of district nursing: a discussion around its professional status and symbolic capital.

This paper examines the significant historical and political influences on district nursing and its representation in terms of employability and education today. Using Bourdieu's theory of habitus and field, the author looks at how district nursing has been positioned in terms of a profession since its establishment. District nursing's profile and value within the NHS has declined in recent years, resulting in reduced district nurse education opportunities and funding from government.

Prevalence of quitting decision and the impact of increased cigarette prices on the smoking behaviours among the male garment workers in Bangladesh.

Objectives: The prevalence of tobacco use is high in Bangladesh, with a cigarette being the most consumed tobacco product. Taxing tobacco is highly effective for tobacco control, raising costs and encouraging smokers to quit or reduce cigarette consumption. Garment workers are the major group of low-wage earners in Bangladesh.

Structure-optimized sgRNA selection with PlatinumCRISPr for efficient Cas9 generation of knockouts.

A single guide RNA (sgRNA) directs Cas9 nuclease for gene-specific scission of double-stranded DNA. High Cas9 activity is essential for efficient gene editing to generate gene deletions and gene replacements by homologous recombination. However, cleavage efficiency is below 50% for more than half of randomly selected sgRNA sequences in human cell culture screens or model organisms.

Determining the minimal important change of the recap of atopic eczema (RECAP) instrument in clinical trials.

Background: The Recap of atopic eczema (RECAP) is a patient-reported instrument designed to assess eczema control. There is a lack of evidence on the interpretability of change scores in clinical trials.

Objectives: To calculate the smallest detectable change (SDC) in RECAP and estimate the minimal important change (MIC) for RECAP using various calculation methods in three eczema clinical trial datasets.

Structural Damage Detection Using PZT Transmission Line Circuit Model.

Arrangements of piezoelectric transducers, such as PZT (lead zirconate titanate), have been widely used in numerous structural health monitoring (SHM) applications. Usually, when two or more PZT transducers are placed close together, significant interference, namely crosstalk, appears. Such an effect is usually neglected in most SHM applications.

The Effects of Combined Versus Single-Mode Resistance and Repeated Sprint Training on Physical Fitness, Hematological Parameters, and Plasma Volume Variations in Highly Trained Soccer Players.

We examined the effects of eight weeks of single-mode resistance, repeated sprint training, and the combination of the two programs on selected measures of physical fitness (muscle power, speed, and body composition), hematological parameters, and plasma volume variations in highly trained soccer players. Sixty male soccer players from the Tunisian national Ligue were randomly allocated to a resistance training group (RTG), a repeated sprint training group (RSTG), a combined resistance and repeated sprint training group (CTG), or an active control group (CG, soccer training only). The training volumes were similar between groups.

Where Do We Draw the Line? Perceptions of Abuse of Older Adults and Their Association With Ageism.

Objectives: Violence against older adults is a prevalent global harm, and there is evidence that perceptions of violence toward older adults may affect reporting and intervention. The present study examines the perception of violence against older adults in contrast to violence against other age groups and investigates the role of ageism in those perceptions.

Methods: A total of 290 participants were surveyed and asked to indicate whether they perceived 15 abusive behaviors reflecting physical, psychological, sexual, and financial abuse and neglect to be abuse toward either an older adult (age 60+), adult, or child.

Delphi definition of general practice/family medicine specialty for a post-COVID world: in-person and remote care delivery.

Introduction: The evolving landscape of general practice (GP)/family medicine (FM) in the post-COVID-19 era, focussing on integrating telemedicine and remote consultations requires a new definition for this specialty. Hence, a broader consensus-based definition of post-COVID-19 GP/FM is warranted.

Methods: This study involved a modified electronic Delphi technique involving 27 specialists working in primary care recruited via convenient and snowball sampling.

No, thank you: reasons for withdrawal from older adult abuse support services.

This study explored the prevalence, reasons, and predictors of service withdrawal by victims in a sample of 151 older adult abuse cases reported to a specialist social work service. Withdrawal occurred in 34% of cases, after an average of 3 months of contact. The most common reasons for withdrawal were victim denial of abuse and unwillingness to engage with the intervention plan.

Phage Therapy Against Antibiotic-Resistant and Multidrug-Resistant Infections Involving Nonhealing Wounds and Prosthetic Joint Infections Associated With Biofilms: A Mini-Review.

Chronic wounds and prosthetic joint infections are difficult to treat and are associated with a high burden of disease and economic cost. The rise of antibiotic resistance and the understanding of biofilm formation has inflamed an already challenging situation. Bacteriophage therapy has been used throughout the last century to treat bacterial infections.

Exploring the moderating role of health-promoting behaviours and self-compassion on the relationship between clinical decision-making and nurses' well-being.

Background: Clinical decision-making is an essential part of the nursing role and has implications for both patient care and nurses' well-being.

Aim: This study aimed to explore the relationship between nurses' perceptions of clinical decision-making ability and moral distress across a nursing population, and the potential link to self-compassion and health-promoting behaviours.

Methods: A self-report questionnaire was distributed to a sample of nurses ( = 152) from April to September 2022.

Enhancing clinical microbiology for genomic surveillance of antimicrobial resistance implementation in Africa.

Surveillance is essential in the fight against antimicrobial resistance (AMR), to monitor the extent of resistance, inform prevention, control measures, and evaluate intervention progress. Traditional surveillance methods based on phenotypic antimicrobial susceptibility data offer important but limited insights into resistance mechanisms, transmission networks, and spread patterns of resistant bacterial strains. Fortunately, genomic technologies are increasingly accessible and can overcome these limitations.